期刊
PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY
卷 96, 期 1-3, 页码 3-18出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.pbiomolbio.2007.07.012
关键词
cardiac electrical modeling; bidomain model; multigrid; preconditioning
资金
- Austrian Science Fund FWF [F 3210] Funding Source: Medline
- Austrian Science Fund (FWF) [F 3201] Funding Source: researchfish
The bidomain equations are widely used for the simulation of electrical activity in cardiac tissue. They are especially important for accurately modeling extracellular stimulation, as evidenced by their prediction of virtual electrode polarization before experimental verification. However, solution of the equations is computationally expensive due to the fine spatial and temporal discretization needed. This limits the size and duration of the problem which can be modeled. Regardless of the specific form into which they are cast, the computational bottleneck becomes the repeated solution of a large, linear system. The purpose of this review is to give an overview of the equations and the methods by which they have been solved. Of particular note are recent developments in multigrid methods, which have proven to be the most efficient. (C) 2007 Elsevier Ltd. All rights reserved.
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