4.8 Article

Unravelling the hidden ancestry of American admixed populations

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NATURE COMMUNICATIONS
卷 6, 期 -, 页码 -

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NATURE PORTFOLIO
DOI: 10.1038/ncomms7596

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资金

  1. Sir Henry Dale Fellowship
  2. Wellcome Trust [098387/Z/12/Z, 098386/Z/12/Z]
  3. Royal Society [098386/Z/12/Z]
  4. NIH
  5. Wellcome Trust [098386/Z/12/Z, 098387/Z/12/Z] Funding Source: Wellcome Trust

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The movement of people into the Americas has brought different populations into contact, and contemporary American genomes are the product of a range of complex admixture events. Here we apply a haplotype-based ancestry identification approach to a large set of genome-wide SNP data from a variety of American, European and African populations to determine the contributions of different ancestral populations to the Americas. Our results provide a fine-scale characterization of the source populations, identify a series of novel, previously unreported contributions from Africa and Europe and highlight geohistorical structure in the ancestry of American admixed populations.

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