相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Targeting the Hedgehog-Glioma-Associated Oncogene Homolog Pathway Inhibits Bleomycin-Induced Lung Fibrosis in Mice
Elika Farrokhi Moshai et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2014)
Genome Sequencing of SHH Medulloblastoma Predicts Genotype-Related Response to Smoothened Inhibition
Marcel Kool et al.
CANCER CELL (2014)
Differential regulation of Gli proteins by Sufu in the lung affects PDGF signaling and myofibroblast development
Chuwen Lin et al.
DEVELOPMENTAL BIOLOGY (2014)
Epigenetic targeting of Hedgehog pathway transcriptional output through BET bromodomain inhibition
Yujie Tang et al.
NATURE MEDICINE (2014)
Dosage-Dependent Regulation of Pancreatic Cancer Growth and Angiogenesis by Hedgehog Signaling
Esha Mathew et al.
CELL REPORTS (2014)
The Yes-associated protein controls the cell density regulation of Hedgehog signaling
M. Tariki et al.
ONCOGENESIS (2014)
Triplication of DYRK1A causes retinal structural and functional alterations in Down syndrome
Ariadna Laguna et al.
HUMAN MOLECULAR GENETICS (2013)
Loss of the Transcription Factor GLI1 Identifies a Signaling Network in the Tumor Microenvironment Mediating KRAS Oncogene-induced Transformation
Lisa D. Mills et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Sleeping Beauty mutagenesis in a mouse medulloblastoma model defines networks that discriminate between human molecular subgroups
Laura A. Genovesi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Dyrk1A negatively regulates the actin cytoskeleton through threonine phosphorylation of N-WASP
Joongkyu Park et al.
JOURNAL OF CELL SCIENCE (2012)
Sleeping Beauty mutagenesis reveals cooperating mutations and pathways in pancreatic adenocarcinoma
Karen M. Mann et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
The Hedgehog Signal Transduction Network
David J. Robbins et al.
SCIENCE SIGNALING (2012)
Trisomy 21 and early brain development
Tarik F. Haydar et al.
TRENDS IN NEUROSCIENCES (2012)
Tumorigenesis in Down's syndrome: big lessons from a small chromosome
Dean Nizetic et al.
NATURE REVIEWS CANCER (2012)
Transient expression of Mnb/Dyrk1a couples cell cycle exit and differentiation of neuronal precursors by inducing p27KIP1 expression and suppressing NOTCH signaling
Barbara Haemmerle et al.
DEVELOPMENT (2011)
MNB/DYRK1A as a multiple regulator of neuronal development
Francisco J. Tejedor et al.
FEBS JOURNAL (2011)
Activation, regulation, and inhibition of DYRK1A
Walter Becker et al.
FEBS JOURNAL (2011)
Role of YAP/TAZ in mechanotransduction
Sirio Dupont et al.
NATURE (2011)
A crucial requirement for Hedgehog signaling in small cell lung cancer
Kwon-Sik Park et al.
NATURE MEDICINE (2011)
Regulation of the alternative splicing of tau exon 10 by SC35 and Dyrk1A
Wei Qian et al.
NUCLEIC ACIDS RESEARCH (2011)
Dual role of Brg chromatin remodeling factor in Sonic hedgehog signaling during neural development
Xiaoming Zhan et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Suppressor of fused and Spop regulate the stability, processing and function of Gli2 and Gli3 full-length activators but not their repressors
Chengbing Wang et al.
DEVELOPMENT (2010)
A mechanism for vertebrate Hedgehog signaling: recruitment to cilia and dissociation of SuFu-Gli protein complexes
Hanna Tukachinsky et al.
JOURNAL OF CELL BIOLOGY (2010)
Dyrk1A Overexpression Inhibits Proliferation and Induces Premature Neuronal Differentiation of Neural Progenitor Cells
Odessa Yabut et al.
JOURNAL OF NEUROSCIENCE (2010)
Histone deacetylase and Cullin3-RENKCTD11 ubiquitin ligase interplay regulates Hedgehog signalling through Gli acetylation
Gianluca Canettieri et al.
NATURE CELL BIOLOGY (2010)
Linking actin dynamics and gene transcription to drive cellular motile functions
Eric N. Olson et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2010)
DYRK1B-dependent autocrine-to-paracrine shift of Hedgehog signaling by mutant RAS
Matthias Lauth et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2010)
Activation of the hedgehog pathway confers a poor prognosis in embryonal and fusion gene-negative alveolar rhabdomyosarcoma
A. Zibat et al.
ONCOGENE (2010)
Harmine specifically inhibits protein kinase DYRK1A and interferes with neurite formation
Nora Goeckler et al.
FEBS JOURNAL (2009)
Cilium-independent regulation of Gli protein function by Sufu in Hedgehog signaling is evolutionarily conserved
Miao-Hsueh Chen et al.
GENES & DEVELOPMENT (2009)
Role of Jhdm2a in regulating metabolic gene expression and obesity resistance
Keisuke Tateishi et al.
NATURE (2009)
Hedgehog signaling is restricted to the stromal compartment during pancreatic carcinogenesis
Hua Tian et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Parallel RNAi screens across different cell lines identify generic and cell type-specific regulators of actin organization and cell morphology
Tao Liu et al.
GENOME BIOLOGY (2009)
Novel human glioma-associated oncogene 1 (GLI1) splice variants reveal distinct mechanisms in the terminal transduction of the hedgehog signal
Takashi Shimokawa et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Identification and characterization of a general nuclear translocation signal in signaling proteins
Dana Chuderland et al.
MOLECULAR CELL (2008)
Trisomy represses ApcMin-mediated tumours in mouse models of Down's syndrome
Thomas E. Sussan et al.
NATURE (2008)
A paracrine requirement for hedgehog signalling in cancer
Robert L. Yauch et al.
NATURE (2008)
The histone demethylase, jmjd1a, interacts with the myocardin factors to regulate SMC differentiation marker gene expression
Kashelle Lockman et al.
CIRCULATION RESEARCH (2007)
Gene expression profiling in the adult Down syndrome brain
H. E. Lockstone et al.
GENOMICS (2007)
A novel role of Brg1 in the regulation of SRF/MRTFA-dependent smooth muscle-specific gene expression
Min Zhang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Two novel members of the ABLIM protein family, ABLIM-2 and -3, associate with STARS and directly bind F-actin
Tomasa Barrientos et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Steroid receptor coactivator 3 is a coactivator for myocardin, the regulator of smooth muscle transcription and differentiation
Hui Joyce Li et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Frequent requirement of hedgehog signaling in non-small cell lung carcinoma
Z. Yuan et al.
ONCOGENE (2007)
Numb is a suppressor of Hedgehog signalling and targets Gli1 for Itch- dependent ubiquitination
Lucia Di Marcotullio et al.
NATURE CELL BIOLOGY (2006)
Acute myeloid leukemia-associated Mkl1 (Mrtf-a) is a key regulator of mammary gland function
Yi Sun et al.
MOLECULAR AND CELLULAR BIOLOGY (2006)
DYRKIA BAC transgenic mice show altered synaptic plasticity with learning and memory defects
Kyoung-Jin Ahn et al.
NEUROBIOLOGY OF DISEASE (2006)
Genetic elimination of suppressor of fused reveals an essential repressor function in the mammalian Hedgehog signaling pathway
J Svärd et al.
DEVELOPMENTAL CELL (2006)
Defective cerebellar response to mitogenic Hedgehog signaling in Down's syndrome mice
RJ Roper et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Brain as a paradigm of organ growth: Hedgehog-Gli signaling in neural stem cells and brain tumors
B Stecca et al.
JOURNAL OF NEUROBIOLOGY (2005)
Gli1 is important for medulloblastoma formation in Ptc1+/- mice
H Kimura et al.
ONCOGENE (2005)
Trp53R172H and KraSG12D cooperate to promote chromosomal instability and widely metastatic pancreatic ductal adenocarcinoma in mice
SR Hingorani et al.
CANCER CELL (2005)
Met proto-oncogene and insulin-like growth factor binding protein 3 overexpression correlates with metastatic ability in well-differentiated pancreatic endocrine neoplasms
DE Hansel et al.
CLINICAL CANCER RESEARCH (2004)
Characterization of the physical interaction of Gli proteins with SUFU proteins
M Dunaeva et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Regulation of Gli1 transcriptional activity in the nucleus by Dyrk1
JH Mao et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Differentially expressed genes identified in human melanoma cell lines with different metastatic behaviour using high density oligonucleotide arrays
NJW de Wit et al.
MELANOMA RESEARCH (2002)
Neurodevelopmental delay, motor abnormalities and cognitive deficits in transgenic mice overexpressing Dyrk1A (minibrain), a murine model of Down's syndrome
X Altafaj et al.
HUMAN MOLECULAR GENETICS (2001)