期刊
PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
卷 275, 期 1647, 页码 2111-2115出版社
ROYAL SOC
DOI: 10.1098/rspb.2008.0294
关键词
discovery curve; emerging infectious diseases; public health; surveillance; virus species
资金
- Biotechnology and Biological Sciences Research Council Funding Source: Medline
- Wellcome Trust Funding Source: Medline
On average, more than two new species of human virus are reported every year. We constructed the cumulative species discovery curve for human viruses going back to 1901. We fitted a statistical model to these data; the shape of the curve strongly suggests that the process of virus discovery is far from complete. We generated a 95% credible interval for the pool of as yet undiscovered virus species of 38-562. We extrapolated the curve and generated an estimate of 10-40 new species to be discovered by 2020. Although we cannot predict the level of health threat that these new viruses will present, we conclude that novel virus species must be anticipated in public health planning. More systematic virus discovery programmes, covering both humans and potential animal reservoirs of human viruses, should be considered.
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