期刊
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
卷 111, 期 44, 页码 15752-15755出版社
NATL ACAD SCIENCES
DOI: 10.1073/pnas.1418548111
关键词
motility; molecular motor; switch; nanogold
资金
- National Natural Science Foundation of China [11374282]
- Fundamental Research Funds for the Central Universities [WK2030020023]
- National Institutes of Health [AI016478]
- Chinese Government
Switching dynamics of flagellar motors of Escherichia coli is commonly observed through markers attached to the flagellar filaments. To eliminate possible complications resulting from the conformational transitions of these filaments and to look at the output of motors more directly, we monitored motor rotation by attaching nanogold spheres to the hooks of cells lacking filaments. We observed exponentially distributed counterclockwise (CCW) and clockwise (CW) intervals and Lorentzian power spectra of the switching time series consistent with models that treat motor switching as a two-state Poisson process.
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