期刊
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
卷 111, 期 47, 页码 16796-16801出版社
NATL ACAD SCIENCES
DOI: 10.1073/pnas.1412662111
关键词
Metarhizium; speciation; transitional species; host specificity; genomic features
资金
- Strategic Priority Research Program of the Chinese Academy of Sciences [XDB11030100]
- National Nature Science Foundation of China [31225023]
- United States National Science Foundation [1257685]
- Direct For Biological Sciences
- Division Of Integrative Organismal Systems [1257685] Funding Source: National Science Foundation
Much remains unknown regarding speciation. Host-pathogen interactions are a major driving force for diversification, but the genomic basis for speciation and host shifting remains unclear. The fungal genus Metarhizium contains species ranging from specialists with very narrow host ranges to generalists that attack a wide range of insects. By genomic analyses of seven species, we demonstrated that generalists evolved from specialists via transitional species with intermediate host ranges and that this shift paralleled insect evolution. We found that specialization was associated with retention of sexuality and rapid evolution of existing protein sequences whereas generalization was associated with protein-family expansion, loss of genome-defense mechanisms, genome restructuring, horizontal gene transfer, and positive selection that accelerated after reinforcement of reproductive isolation. These results advance understanding of speciation and genomic signatures that underlie pathogen adaptation to hosts.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据