相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。JAK/STAT signaling in hematological malignancies
W. Vainchenker et al.
ONCOGENE (2013)
Genetic Alterations Activating Kinase and Cytokine Receptor Signaling in High-Risk Acute Lymphoblastic Leukemia
Kathryn G. Roberts et al.
CANCER CELL (2012)
Counteracting Effects Operating on Src Homology 2 Domain-containing Protein-tyrosine Phosphatase 2 (SHP2) Function Drive Selection of the Recurrent Y62D and Y63C Substitutions in Noonan Syndrome
Simone Martinelli et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
The genetic basis of early T-cell precursor acute lymphoblastic leukaemia
Jinghui Zhang et al.
NATURE (2012)
Essential role for Ptpn11 in survival of hematopoietic stem and progenitor cells
Gordon Chan et al.
BLOOD (2011)
Stem cell gene expression programs influence clinical outcome in human leukemia
Kolja Eppert et al.
NATURE MEDICINE (2011)
Assessing the risk of second malignancies after modern radiotherapy
Wayne D. Newhauser et al.
NATURE REVIEWS CANCER (2011)
Novel mutations in the inhibitory adaptor protein LNK drive JAK-STAT signaling in patients with myeloproliferative neoplasms
Stephen T. Oh et al.
BLOOD (2010)
A germline gain-of-function mutation in Ptpn11 (Shp-2) phosphatase induces myeloproliferative disease by aberrant activation of hematopoietic stem cells
Dan Xu et al.
BLOOD (2010)
Immunity, Inflammation, and Cancer
Sergei I. Grivennikov et al.
CELL (2010)
A Distinctive DNA Damage Response in Human Hematopoietic Stem Cells Reveals an Apoptosis-Independent Role for p53 in Self-Renewal
Michael Milyavsky et al.
CELL STEM CELL (2010)
Intermediate-Term Hematopoietic Stem Cells with Extended but Time-Limited Reconstitution Potential
Patricia Benveniste et al.
CELL STEM CELL (2010)
Lnk constrains myeloproliferative diseases in mice
Alexey Bersenev et al.
JOURNAL OF CLINICAL INVESTIGATION (2010)
LNK mutation studies in blast-phase myeloproliferative neoplasms, and in chronic-phase disease with TET2, IDH, JAK2 or MPL mutations
A. Pardanani et al.
LEUKEMIA (2010)
Leukemogenic Ptpn11 causes fatal myeloproliferative disorder via cell-autonomous effects on multiple stages of hematopoiesis
Gordon Chan et al.
BLOOD (2009)
Structural coupling of SH2-kinase domains links fes and Abl substrate recognition and kinase activation
Panagis Filippakopoulos et al.
CELL (2008)
Lnk negatively regulates self-renewal of hematopoietic stem cells by modifying thrombopoietin-mediated signal transduction
Jun Seita et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
PTPN11 is the first identified proto-oncogene that encodes a tyrosine phosphatase
Rebecca J. Chan et al.
BLOOD (2007)
A change in conformational dynamics underlies the activation of Eph receptor tyrosine kinases
Silke Wiesner et al.
EMBO JOURNAL (2006)
Cytokines regulate postnatal hematopoietic stem cell expansion: opposing roles of thrombopoietin and LNK
Natalija Buza-Vidas et al.
GENES & DEVELOPMENT (2006)
Chronic activation of protein kinase Bβ/Akt2 leads to multinucleation and cell fusion in human epithelial kidney cells:: events associated with tumorigenesis
J Jin et al.
ONCOGENE (2005)
Lnk inhibits erythropoiesis and Epo-dependent JAK2 activation and downstream signaling pathways
W Tong et al.
BLOOD (2005)
Quantification of self-renewal capacity in single hematopoietic stem cells from normal and lnk-deficient mice
H Ema et al.
DEVELOPMENTAL CELL (2005)
Cytokine signaling and hematopoietic homeostasis are disrupted in Lnk-deficient mice
L Velazquez et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2002)
Mutations in PTPN11, encoding the protein tyrosine phosphatase SHP-2, cause Noonan syndrome
M Tartaglia et al.
NATURE GENETICS (2001)
Control of B cell production by the adaptor protein Lnk: Definition of a conserved family of signal-modulating proteins
S Takaki et al.
IMMUNITY (2000)
Cloning and characterization of human Lnk, an adaptor protein with pleckstrin homology and Src homology 2 domains that can inhibit T cell activation
YJ Li et al.
JOURNAL OF IMMUNOLOGY (2000)
The SH2 tyrosine phosphatase Shp2 is required for mammalian limb development
TM Saxton et al.
NATURE GENETICS (2000)