相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Structural Basis of ss-Amyloid-Dependent Synaptic Dysfunctions
Christian Haupt et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2012)
Structure-based design of conformation- and sequence-specific antibodies against amyloid β
Joseph M. Perchiacca et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Antiparallel β-sheet architecture in Iowa-mutant β-amyloid fibrils
Wei Qiang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Atomic View of a Toxic Amyloid Small Oligomer
Arthur Laganowsky et al.
SCIENCE (2012)
Solid-State NMR Spectroscopic Investigation of A beta Protofibrils: Implication of a beta-Sheet Remodeling upon Maturation into Terminal Amyloid Fibrils
Holger A. Scheidt et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2011)
Phosphate and HEPES buffers potently affect the fibrillation and oligomerization mechanism of Alzheimer's Aβ peptide
Megan Garvey et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2011)
Assembly of Alzheimer's Aβ peptide into nanostructured amyloid fibrils
Isabel Morgado et al.
CURRENT OPINION IN COLLOID & INTERFACE SCIENCE (2011)
Aβ42 Neurotoxicity Is Mediated by Ongoing Nucleated Polymerization Process Rather than by Discrete Aβ42 Species
Asad Jan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Amyloid Fibril Recognition with the Conformational B10 Antibody Fragment Depends on Electrostatic Interactions
Christian Haupt et al.
JOURNAL OF MOLECULAR BIOLOGY (2011)
Pattern Recognition with a Fibril-Specific Antibody Fragment Reveals the Surface Variability of Natural Amyloid Fibrils
Christian Haupt et al.
JOURNAL OF MOLECULAR BIOLOGY (2011)
Amyloid-β forms fibrils by nucleated conformational conversion of oligomers
Jiyong Lee et al.
NATURE CHEMICAL BIOLOGY (2011)
Molecular basis for amyloid-β polymorphism
Jacques-Philippe Colletier et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Size-dependent neurotoxicity of β-amyloid oligomers
Paulius Cizas et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2010)
Amyloid β-Protein Dimers Rapidly Form Stable Synaptotoxic Protofibrils
Brian O'Nuallain et al.
JOURNAL OF NEUROSCIENCE (2010)
Structural conversion of neurotoxic amyloid-β1-42 oligomers to fibrils
Mahiuddin Ahmed et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2010)
Stabilization of neurotoxic Alzheimer amyloid-β oligomers by protein engineering
Anders Sandberg et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Biology of Amyloid: Structure, Function, and Regulation
Jason Greenwald et al.
STRUCTURE (2010)
Sequestration of the Aβ Peptide Prevents Toxicity and Promotes Degradation In Vivo
Leila M. Luheshi et al.
PLOS BIOLOGY (2010)
Annular Protofibrils Are a Structurally and Functionally Distinct Type of Amyloid Oligomer
Rakez Kayed et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Comparison of Alzheimer Aβ(1-40) and Aβ(1-42) amyloid fibrils reveals similar protofilament structures
Matthias Schmidt et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
α-Helix targeting reduces amyloid-β peptide toxicity
C. Nerelius et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Structure-neurotoxicity relationships of amyloid β-protein oligomers
Kenjiro Ono et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Amyloid-β protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory
Ganesh M. Shankar et al.
NATURE MEDICINE (2008)
Paired β-sheet structure of an Aβ(1-40) amyloid fibril revealed by electron microscopy
Carsten Sachse et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Molecular structural basis for polymorphism in Alzheimer's β-amyloid fibrils
Anant K. Paravastu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Directed selection of a conformational antibody domain that prevents mature amyloid fibril formation by stabilizing Aβ protofibrils
Gernot Habicht et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Evidence of fibril-like β-sheet structures in a neurotoxic amyloid intermediate of Alzheimer's β-amyloid
Sandra Chimon et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2007)
Aβ oligomers induce neuronal oxidative stress through an N-methyl-D-aspartate receptor-dependent mechanism that is blocked by the Alzheimer drug memantine
Fernanda G. De Felice et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Soluble protein oligomers in neurodegeneration:: lessons from the Alzheimer's amyloid β-peptide
Christian Haass et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2007)
Amyloid-beta aggregation
Verena H. Finder et al.
NEURODEGENERATIVE DISEASES (2007)
Demonstration of a common artifact in immunosorbent assays of brain extracts:: Development of a solid-phase extraction protocol to enable measurement of amyloid-β from wild-type rodent brain
Thomas A. Lanz et al.
JOURNAL OF NEUROSCIENCE METHODS (2006)
Distinct early folding and aggregation properties of Alzheimer amyloid-β peptides Aβ40 and Aβ42 -: Stable trimer or tetramer formation by Aβ42
Yun-Ru Chen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
A specific amyloid-β protein assembly in the brain impairs memory
S Lesné et al.
NATURE (2006)
Globular amyloid β-peptide1-42 oligomer -: a homogenous and stable neuropathological protein in Alzheimer's disease
S Barghorn et al.
JOURNAL OF NEUROCHEMISTRY (2005)
Mutagenic analysis of the nucleation propensity of oxidized Alzheimer's β-amyloid peptide
T Christopeit et al.
PROTEIN SCIENCE (2005)
Evidence of the existence of micelles in the fibrillogenesis of β-amyloid peptide
R Sabaté et al.
JOURNAL OF PHYSICAL CHEMISTRY B (2005)
Synaptic plasticity in animal models of early Alzheimer's disease
MJ Rowan et al.
PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES (2003)
Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis
R Kayed et al.
SCIENCE (2003)
Aβ toxicity in Alzheimer's disease:: globular oligomers (ADDLs) as new vaccine and drug targets
WL Klein
NEUROCHEMISTRY INTERNATIONAL (2002)
Naturally secreted oligomers of amyloid β protein potently inhibit hippocampal long-term potentiation in vivo
DM Walsh et al.
NATURE (2002)
Conformational Abs recognizing a generic amyloid fibril epitope
B O'Nuallain et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Structure determination of micelle-like intermediates in amyloid β-protein fibril assembly by using small angle neutron scattering
W Yong et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)