相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Structure-Based Discovery of a Novel Inhibitor Targeting the β-Catenin/Tcf4 Interaction
Wang Tian et al.
BIOCHEMISTRY (2012)
Wnt/β-Catenin Signaling and Disease
Hans Clevers et al.
CELL (2012)
Structure of the Stapled p53 Peptide Bound to Mdm2
Sohee Baek et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2012)
A diterpenoid derivative 15-oxospiramilactone inhibits Wnt/β-catenin signaling and colon cancer cell tumorigenesis
Wei Wang et al.
CELL RESEARCH (2011)
Synthesis of all-hydrocarbon stapled α-helical peptides by ring-closing olefin metathesis
Young-Woo Kim et al.
NATURE PROTOCOLS (2011)
Targeting cancer stem cells by inhibiting Wnt, notch, and Hedgehog pathways
Naoko Takebe et al.
NATURE REVIEWS CLINICAL ONCOLOGY (2011)
Salinomycin inhibits Wnt signaling and selectively induces apoptosis in chronic lymphocytic leukemia cells
Desheng Lu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
An RNAi-based chemical genetic screen identifies three small-molecule inhibitors of the Wnt/wingless signaling pathway
Foster C. Gonsalves et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
A Stapled p53 Helix Overcomes HDMX-Mediated Suppression of p53
Federico Bernal et al.
CANCER CELL (2010)
Small-molecule inhibition of Wnt signaling through activation of casein kinase 1α
Curtis A. Thorne et al.
NATURE CHEMICAL BIOLOGY (2010)
The MCL-1 BH3 helix is an exclusive MCL-1 inhibitor and apoptosis sensitizer
Michelle L. Stewart et al.
NATURE CHEMICAL BIOLOGY (2010)
Hydrocarbon double-stapling remedies the proteolytic instability of a lengthy peptide therapeutic
Gregory H. Bird et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling
Shih-Min A. Huang et al.
NATURE (2009)
Direct inhibition of the NOTCH transcription factor complex
Raymond E. Moellering et al.
NATURE (2009)
Small molecule-mediated disruption of Wnt-dependent signaling in tissue regeneration and cancer
Baozhi Chen et al.
NATURE CHEMICAL BIOLOGY (2009)
Predicting cell-penetrating peptides
Mats Hansen et al.
ADVANCED DRUG DELIVERY REVIEWS (2008)
Solution structure of a hydrocarbon stapled peptide inhibitor in complex with monomeric C-terminal domain of HIV-1 capsid
Shibani Bhattacharya et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
BAX activation is initiated at a novel interaction site
Evripidis Gavathiotis et al.
NATURE (2008)
Dual role of proapoptotic BAD in insulin secretion and beta cell survival
Nika N. Danial et al.
NATURE MEDICINE (2008)
Reactivation of the p53 tumor suppressor pathway by a stapled p53 peptide
Federico Bernal et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2007)
Crystal structure of a β-catenin/BCL9/Tcf4 complex
James Sampietro et al.
MOLECULAR CELL (2006)
Identification of a specific inhibitor of the dishevelled PDZ domain
JF Shan et al.
BIOCHEMISTRY (2005)
Activation of apoptosis in vivo by a hydrocarbon-stapled BH3 helix
LD Walensky et al.
SCIENCE (2004)
A small molecule inhibitor of β-catenin/cyclic AMP response element-binding protein transcription
KH Emami et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Small-molecule antagonists of the oncogenic Tcf/beta-catenin protein complex
M Lepourcelet et al.
CANCER CELL (2004)
Crystal structure of a β-catenin/axin complex suggests a mechanism for the β-catenin destruction complex
Y Xing et al.
GENES & DEVELOPMENT (2003)
Reduced expression of Axin correlates with tumour progression of oesophageal squamous cell carcinoma
M Nakajima et al.
BRITISH JOURNAL OF CANCER (2003)
The β-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells
M van de Wetering et al.
CELL (2002)
A γ-secretase inhibitor blocks Notch signaling in vivo and causes a severe neurogenic phenotype in zebrafish
A Geling et al.
EMBO REPORTS (2002)
Genetics of colorectal cancer: hereditary aspects and overview of colorectal tumorigenesis
NS Fearnhead et al.
BRITISH MEDICAL BULLETIN (2002)
The structure of the β-catenin/E-cadherin complex and the molecular basis of diverse ligand recognition by β-catenin
AH Huber et al.
CELL (2001)
Crystal structure of a β-catenin/Tcf complex
TA Graham et al.
CELL (2000)
An all-hydrocarbon cross-linking system for enhancing the helicity and metabolic stability of peptides
CE Schafmeister et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2000)