4.8 Article

Mutant induced pluripotent stem cell lines recapitulate aspects of TDP-43 proteinopathies and reveal cell-specific vulnerability

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Cell & Tissue Engineering

LRRK2 Mutant iPSC-Derived DA Neurons Demonstrate Increased Susceptibility to Oxidative Stress

Ha Nam Nguyen et al.

CELL STEM CELL (2011)

Article Biochemistry & Molecular Biology

TDP-43 regulates its mRNA levels through a negative feedback loop

Youhna M. Ayala et al.

EMBO JOURNAL (2011)

Article Clinical Neurology

TDP-43-Based Animal Models of Neurodegeneration: New Insights into ALS Pathology and Pathophysiology

Iga Wegorzewska et al.

NEURODEGENERATIVE DISEASES (2011)

Article Multidisciplinary Sciences

Human stem cells as a model of motoneuron development and diseases

Yan Liu et al.

NEURONS AND NETWORKS IN THE SPINAL CORD (2010)

Article Biochemistry & Molecular Biology

Knockdown of transactive response DNA-binding protein (TDP-43) downregulates histone deacetylase 6

Fabienne C. Fiesel et al.

EMBO JOURNAL (2010)

Review Biochemistry & Molecular Biology

TDP-43 and FUS/TLS: emerging roles in RNA processing and neurodegeneration

Clotilde Lagier-Tourenne et al.

HUMAN MOLECULAR GENETICS (2010)

Article Multidisciplinary Sciences

Patient-specific induced pluripotent stem-cell-derived models of LEOPARD syndrome

Xonia Carvajal-Vergara et al.

NATURE (2010)

Article Multidisciplinary Sciences

ALS-associated mutations in TDP-43 increase its stability and promote TDP-43 complexes with FUS/TLS

Shuo-Chien Ling et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

Article Multidisciplinary Sciences

Neural differentiation of human induced pluripotent stem cells follows developmental principles but with variable potency

Bao-Yang Hu et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

Editorial Material Clinical Neurology

Nomenclature for neuropathologic subtypes of frontotemporal lobar degeneration: consensus recommendations

Ian R. A. Mackenzie et al.

ACTA NEUROPATHOLOGICA (2009)

Article Biochemical Research Methods

Proteomics Analysis Reveals Novel Components in the Detergent-Insoluble Subproteome in Alzheimer's Disease

Yair M. Gozal et al.

JOURNAL OF PROTEOME RESEARCH (2009)

Article Multidisciplinary Sciences

Induced pluripotent stem cells from a spinal muscular atrophy patient

Allison D. Ebert et al.

NATURE (2009)

Article Biotechnology & Applied Microbiology

Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling

Stuart M. Chambers et al.

NATURE BIOTECHNOLOGY (2009)

Article Clinical Neurology

TDP-43 mutation in familial amyotrophic lateral sclerosis

Akio Yokoseki et al.

ANNALS OF NEUROLOGY (2008)

Article Clinical Neurology

TDP-43 A315T mutation in familial motor neuron disease

Michael A. Gitcho et al.

ANNALS OF NEUROLOGY (2008)

Article Biochemistry & Molecular Biology

TDP-43, the signature protein of FTLD-U, is a neuronal activity-responsive factor

I. -Fan Wang et al.

JOURNAL OF NEUROCHEMISTRY (2008)

Article Clinical Neurology

Concomitant TAR-DNA-binding in Alzheimer disease and protein 43 pathology is present corticobasal degeneration but not in other tauopathies

Kunihiro Uryu et al.

JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2008)

Article Multidisciplinary Sciences

Generation of human induced pluripotent stem cells from dermal fibroblasts

W. E. Lowry et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)

Article Multidisciplinary Sciences

TDP-43 mutations in familial and sporadic amyotrophic lateral sclerosis

Jemeen Sreedharan et al.

SCIENCE (2008)

Article Genetics & Heredity

Novel Mutations in TARDBP(TDP-43) in Patients with Familial Amyotrophic Lateral Sclerosis

Nicola J. Rutherford et al.

PLOS GENETICS (2008)

Article Multidisciplinary Sciences

Reprogramming of human somatic cells to pluripotency with defined factors

In-Hyun Park et al.

NATURE (2008)

Article Biochemistry & Molecular Biology

TDP-43 proteinopathies: Neurodegenerative protein misfolding diseases without amyloidosis

Linda K. Kwong et al.

NEUROSIGNALS (2008)

Article Multidisciplinary Sciences

Induced pluripotent stem cell lines derived from human somatic cells

Junying Yu et al.

SCIENCE (2007)

Article Biochemistry & Molecular Biology

Induction of pluripotent stem cells from adult human fibroblasts by defined factors

Kazutoshi Takahashi et al.

Article Biochemistry & Molecular Biology

TDP-43 is a component of ubiquitin-positive tau-negative inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis

Tetsuaki Arai et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2006)

Article Multidisciplinary Sciences

Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis

Manuela Neumann et al.

SCIENCE (2006)

Article Biochemical Research Methods

Characterization of an RNA granule from developing brain

G Elvira et al.

MOLECULAR & CELLULAR PROTEOMICS (2006)

Article Multidisciplinary Sciences

Automated microscope system for determining factors that predict neuronal fate

M Arrasate et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)

Article Biochemistry & Molecular Biology

Directed differentiation of embryonic stem cells into motor neurons

H Wichterle et al.

Article Biochemistry & Molecular Biology

Inhibition of the ubiquitin-proteasome pathway induces differential heat-shock protein response in cardiomyocytes and renders early cardiac protection

K Stangl et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2002)