相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Atrx promotes heterochromatin formation at retrotransposons
Dennis Sadic et al.
EMBO REPORTS (2015)
Histone H3.3 maintains genome integrity during mammalian development
Chuan-Wei Jang et al.
GENES & DEVELOPMENT (2015)
Histone H3.3 is required for endogenous retroviral element silencing in embryonic stem cells
Simon J. Elsasser et al.
NATURE (2015)
Identification of protein complexes that bind to histone H3 combinatorial modifications using super-SILAC and weighted correlation network analysis
Natalia Kunowska et al.
NUCLEIC ACIDS RESEARCH (2015)
Alternative lengthening of telomeres renders cancer cells hypersensitive to ATR inhibitors
Rachel Litman Flynn et al.
SCIENCE (2015)
CENP-A nucleosomes localize to transcription factor hotspots and subtelomeric sites in human cancer cells
Rajbir K. Athwal et al.
EPIGENETICS & CHROMATIN (2015)
Loss of ATRX, associated with DNA methylation pattern of chromosome end, impacted biological behaviors of astrocytic tumors
Jinquan Cai et al.
ONCOTARGET (2015)
ATRX Plays a Key Role in Maintaining Silencing at Interstitial Heterochromatic Loci and Imprinted Genes
Hsiao P. J. Voon et al.
CELL REPORTS (2015)
ATRX promotes gene expression by facilitating transcriptional elongation through guanine-rich coding regions
Michael A. Levy et al.
HUMAN MOLECULAR GENETICS (2015)
ATRX tolerates activity-dependent histone H3 methyl/phos switching to maintain repetitive element silencing in neurons
Kyung-Min Noh et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Whole-exome sequencing identifies ATRX mutation as a key molecular determinant in lower-grade glioma
Kasthuri Kannan et al.
Oncotarget (2015)
ATRX Directs Binding of PRC2 to Xist RNA and Polycomb Targets
Kavitha Sarma et al.
CELL (2014)
Dynamics of histone H3.3 deposition in proliferating and senescent cells reveals a DAXX-dependent targeting to PML-NBs important for pericentromeric heterochromatin organization
Armelle Corpet et al.
CELL CYCLE (2014)
Loss of DAXX and ATRX Are Associated With Chromosome Instability and Reduced Survival of Patients With Pancreatic Neuroendocrine Tumors
Ilaria Marinoni et al.
GASTROENTEROLOGY (2014)
Decreased Expression of the Chromatin Remodeler ATRX Associates with Melanoma Progression
Zulekha A. Qadeer et al.
JOURNAL OF INVESTIGATIVE DERMATOLOGY (2014)
An H3K9/S10 methyl-phospho switch modulates Polycomb and Pol II binding at repressed genes during differentiation
Pierangela Sabbattini et al.
MOLECULAR BIOLOGY OF THE CELL (2014)
Mislocalization of the Centromeric Histone Variant CenH3/CENP-A in Human Cells Depends on the Chaperone DAXX
Nicolas Lacoste et al.
MOLECULAR CELL (2014)
Analysis of neonatal brain lacking ATRX or MeCP2 reveals changes in nucleosome density, CTCF binding and chromatin looping
Kristin D. Kernohan et al.
NUCLEIC ACIDS RESEARCH (2014)
ATRX Dysfunction Induces Replication Defects in Primary Mouse Cells
David Clynes et al.
PLOS ONE (2014)
Spontaneous slow replication fork progression elicits mitosis alterations in homologous recombination-deficient mammalian cells
Therese Wilhelm et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Use of human embryonic stem cells to model pediatric gliomas with H3.3K27M histone mutation
Kosuke Funato et al.
SCIENCE (2014)
Recurrent Somatic Structural Variations Contribute to Tumorigenesis in Pediatric Osteosarcoma
Xiang Chen et al.
CELL REPORTS (2014)
ATRX is required for maintenance of the neuroprogenitor cell pool in the embryonic mouse brain
Kieran Ritchie et al.
BIOLOGY OPEN (2014)
Reduced H3K27me3 and DNA Hypomethylation Are Major Drivers of Gene Expression in K27M Mutant Pediatric High-Grade Gliomas
Sebastian Bender et al.
CANCER CELL (2013)
An AT-Hook Domain in MeCP2 Determines the Clinical Course of Rett Syndrome and Related Disorders
Steven Andrew Baker et al.
CELL (2013)
The histone H3.3K27M mutation in pediatric glioma reprograms H3K27 methylation and gene expression
Kui-Ming Chan et al.
GENES & DEVELOPMENT (2013)
Clinicopathologic significance of immunostaining of α-thalassemia/mental retardation syndrome X-linked protein and death domain-associated protein in neuroendocrine tumors
Shi-Fan Chen et al.
HUMAN PATHOLOGY (2013)
Alpha Thalassemia/Mental Retardation Syndrome X-linked Gene Product ATRX Is Required for Proper Replication Restart and Cellular Resistance to Replication Stress
Justin Wai-Chung Leung et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Atrx deficiency induces telomere dysfunction, endocrine defects, and reduced life span
L. Ashley Watson et al.
JOURNAL OF CLINICAL INVESTIGATION (2013)
Quantitative visualization of DNA G-quadruplex structures in human cells
Giulia Biffi et al.
NATURE CHEMISTRY (2013)
PML bodies provide an important platform for the maintenance of telomeric chromatin integrity in embryonic stem cells
Fiona T. M. Chang et al.
NUCLEIC ACIDS RESEARCH (2013)
AKT Signaling as a Novel Factor Associated with In Vitro Resistance of Human AML to Gemtuzumab Ozogamicin
David B. Rosen et al.
PLOS ONE (2013)
TERT promoter mutations occur frequently in gliomas and a subset of tumors derived from cells with low rates of self-renewal
Patrick J. Killela et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Inhibition of PRC2 Activity by a Gain-of-Function H3 Mutation Found in Pediatric Glioblastoma
Peter W. Lewis et al.
SCIENCE (2013)
The chromatin remodeller ATRX: a repeat offender in human disease
David Clynes et al.
TRENDS IN BIOCHEMICAL SCIENCES (2013)
Genome-wide incorporation dynamics reveal distinct categories of turnover for the histone variant H3.3
Daniel C. Kraushaar et al.
GENOME BIOLOGY (2013)
Frequent ATRX mutations and loss of expression in adult diffuse astrocytic tumors carrying IDH1/IDH2 and TP53 mutations
Xiao-Yang Liu et al.
ACTA NEUROPATHOLOGICA (2012)
Small Cell and Large Cell Neuroendocrine Carcinomas of the Pancreas are Genetically Similar and Distinct From Well-differentiated Pancreatic Neuroendocrine Tumors
Shinichi Yachida et al.
AMERICAN JOURNAL OF SURGICAL PATHOLOGY (2012)
Hotspot Mutations in H3F3A and IDH1 Define Distinct Epigenetic and Biological Subgroups of Glioblastoma
Dominik Sturm et al.
CANCER CELL (2012)
ATRX-mediated chromatin association of histone variant macroH2A1 regulates α-globin expression
Kajan Ratnakumar et al.
GENES & DEVELOPMENT (2012)
D-2-hydroxyglutarate produced by mutant IDH1 perturbs collagen maturation and basement membrane function
Masato Sasaki et al.
GENES & DEVELOPMENT (2012)
Variant repeats are interspersed throughout the telomeres and recruit nuclear receptors in ALT cells
Dimitri Conomos et al.
JOURNAL OF CELL BIOLOGY (2012)
Linking abnormal mitosis to the acquisition of DNA damage
Neil J. Ganem et al.
JOURNAL OF CELL BIOLOGY (2012)
Compromised genomic integrity impedes muscle growth after Atrx inactivation
Michael S. Huh et al.
JOURNAL OF CLINICAL INVESTIGATION (2012)
DNA breaks and chromosome pulverization from errors in mitosis
Karen Crasta et al.
NATURE (2012)
Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma
Jeremy Schwartzentruber et al.
NATURE (2012)
IDH1(R132H) mutation increases murine haematopoietic progenitors and alters epigenetics
Masato Sasaki et al.
NATURE (2012)
Sequencing of neuroblastoma identifies chromothripsis and defects in neuritogenesis genes
Jan J. Molenaar et al.
NATURE (2012)
Loss of Wild-Type ATRX Expression in Somatic Cell Hybrids Segregates with Activation of Alternative Lengthening of Telomeres
Kylie Bower et al.
PLOS ONE (2012)
Frequent ATRX, CIC, FUBP1 and IDH1 mutations refine the classification of malignant gliomas
Yuchen Jiao et al.
ONCOTARGET (2012)
Loss of ATRX, Genome Instability, and an Altered DNA Damage Response Are Hallmarks of the Alternative Lengthening of Telomeres Pathway
Courtney A. Lovejoy et al.
PLOS GENETICS (2012)
R132H-mutation of isocitrate dehydrogenase-1 is not sufficient for HIF-1α upregulation in adult glioma
Susan C. Williams et al.
ACTA NEUROPATHOLOGICA (2011)
Prevalence of the Alternative Lengthening of Telomeres Telomere Maintenance Mechanism in Human Cancer Subtypes
Christopher M. Heaphy et al.
AMERICAN JOURNAL OF PATHOLOGY (2011)
The oncometabolite 2-hydroxyglutarate inhibits histone lysine demethylases
Rasheduzzaman Chowdhury et al.
EMBO REPORTS (2011)
The ATRX-ADD domain binds to H3 tail peptides and reads the combined methylation state of K4 and K9
Arunkumar Dhayalan et al.
HUMAN MOLECULAR GENETICS (2011)
Functional significance of mutations in the Snf2 domain of ATRX
Matthew Mitson et al.
HUMAN MOLECULAR GENETICS (2011)
ATRX ADD domain links an atypical histone methylation recognition mechanism to human mental-retardation syndrome
Shigeki Iwase et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2011)
Combinatorial readout of histone H3 modifications specifies localization of ATRX to heterochromatin
Sebastian Eustermann et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2011)
Mutations in CIC and FUBP1 Contribute to Human Oligodendroglioma
Chetan Bettegowda et al.
SCIENCE (2011)
New Epigenetic Drivers of Cancers
Simon J. Elsaesser et al.
SCIENCE (2011)
Altered Telomeres in Tumors with ATRX and DAXX Mutations
Christopher M. Heaphy et al.
SCIENCE (2011)
DAXX/ATRX, MEN1, and mTOR Pathway Genes Are Frequently Altered in Pancreatic Neuroendocrine Tumors
Yuchen Jiao et al.
SCIENCE (2011)
Identification of a CpG Island Methylator Phenotype that Defines a Distinct Subgroup of Glioma
Houtan Noushmehr et al.
CANCER CELL (2010)
Distinct Factors Control Histone Variant H3.3 Localization at Specific Genomic Regions
Aaron D. Goldberg et al.
CELL (2010)
ATR-X Syndrome Protein Targets Tandem Repeats and Influences Allele-Specific Expression in a Size-Dependent Manner
Martin J. Law et al.
CELL (2010)
ATRX Taming tandem repeats
Richard J. Gibbons et al.
CELL CYCLE (2010)
Non-B DNA structure-induced genetic instability and evolution
Junhua Zhao et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2010)
ATRX Partners with Cohesin and MeCP2 and Contributes to Developmental Silencing of Imprinted Genes in the Brain
Kristin D. Kernohan et al.
DEVELOPMENTAL CELL (2010)
The death-associated protein DAXX is a novel histone chaperone involved in the replication-independent deposition of H3.3
Pascal Drane et al.
GENES & DEVELOPMENT (2010)
ATRX interacts with H3.3 in maintaining telomere structural integrity in pluripotent embryonic stem cells
Lee H. Wong et al.
GENOME RESEARCH (2010)
The histone variant macroH2A suppresses melanoma progression through regulation of CDK8
Avnish Kapoor et al.
NATURE (2010)
Alternative lengthening of telomeres: models, mechanisms and implications
Anthony J. Cesare et al.
NATURE REVIEWS GENETICS (2010)
Daxx is an H3.3-specific histone chaperone and cooperates with ATRX in replication-independent chromatin assembly at telomeres
Peter W. Lewis et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Loss of Maternal ATRX Results in Centromere Instability and Aneuploidy in the Mammalian Oocyte and Pre-Implantation Embryo
Claudia Baumann et al.
PLOS GENETICS (2010)
HJURP Is a Cell-Cycle-Dependent Maintenance and Deposition Factor of CENP-A at Centromeres
Elaine M. Dunleavy et al.
CELL (2009)
Centromere-Specific Assembly of CENP-A Nucleosomes Is Mediated by HJURP
Daniel R. Foltz et al.
CELL (2009)
ATRX marks the inactive X chromosome (Xi) in somatic cells and during imprinted X chromosome inactivation in trophoblast stem cells
Claudia Baumann et al.
CHROMOSOMA (2009)
A 'higher order' of telomere regulation: telomere heterochromatin and telomeric RNAs
Stefan Schoeftner et al.
EMBO JOURNAL (2009)
Cancer-associated IDH1 mutations produce 2-hydroxyglutarate
Lenny Dang et al.
NATURE (2009)
Surgical management of pancreatic endocrine tumors
Volker Fendrich et al.
NATURE REVIEWS CLINICAL ONCOLOGY (2009)
G-quadruplex structures: in vivo evidence and function
Hans J. Lipps et al.
TRENDS IN CELL BIOLOGY (2009)
The SWI/SNF protein ATRX co-regulates pseudoautosomal genes that have translocated to autosomes in the mouse genome
Michael A. Levy et al.
BMC GENOMICS (2008)
Mutations in the chromatin-associated protein ATRX
Richard J. Gibbons et al.
HUMAN MUTATION (2008)
Loss of ATRX leads to chromosome cohesion and congression defects
Kieran Ritchie et al.
JOURNAL OF CELL BIOLOGY (2008)
Dynamics of component exchange at PML nuclear bodies
Stefanie Weidtkamp-Peters et al.
JOURNAL OF CELL SCIENCE (2008)
Neuronal Death Resulting from Targeted Disruption of the Snf2 Protein ATRX Is Mediated by p53
Claudia Seah et al.
JOURNAL OF NEUROSCIENCE (2008)
The HP1-p150/CAF-1 interaction is required for pericentric heterochromatin replication and S-phase progression in mouse cells
Jean-Pierre Quivy et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2008)
An integrated genomic analysis of human glioblastoma Multiforme
D. Williams Parsons et al.
SCIENCE (2008)
Patient mutations alter ATRX targeting to PML nuclear bodies
Nathalie G. Berube et al.
EUROPEAN JOURNAL OF HUMAN GENETICS (2008)
Structure, dynamics and functions of promyelocytic leukaemia nuclear bodies
Rosa Bernardi et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2007)
Structural consequences of disease-causing mutations in the ATRX-DNMT3-DNMT3L (ADD) domain of the chromatin-associated protein ATRX
Anthony Argentaro et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Nucleosome stability mediated by histone variants H3.3 and H2A.Z
Chunyuan Jin et al.
GENES & DEVELOPMENT (2007)
dXNP, a Drosophila homolog of XNP/ATRX, induces apoptosis via Jun-N-terminal kinase activation
Nam Gon Lee et al.
FEBS LETTERS (2007)
RNAi-dependent and -independent RNA turnover mechanisms contribute to heterochromatic gene silencing
Marc Buehler et al.
CELL (2007)
Interaction between chromatin proteins MECP2 and ATRX is disrupted by mutations that cause inherited mental retardation
Xinsheng Nan et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
A MAPK docking site is critical for downregulation of Capicua by Torso and EGFR RTK signaling
Sergio Astigarraga et al.
EMBO JOURNAL (2007)
The DNA damage machinery and homologous recombination pathway act consecutively to protect human telomeres
Ramiro E. Verdun et al.
CELL (2006)
Telomere maintenance mechanisms in liposarcomas:: Association with histologic subtypes and disease progression
Aurora Costa et al.
CANCER RESEARCH (2006)
PML nuclear bodies are highly organised DNA-protein structures with a function in heterochromatin remodelling at the G2 phase
Judith J. Luciani et al.
JOURNAL OF CELL SCIENCE (2006)
Epigenetic regulation of mammalian pericentric heterochromatin in vivo by HP1
N Kourmouli et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2005)
Functional human telomeres are recognized as DNA damage in G2 of the cell cycle
RE Verdun et al.
MOLECULAR CELL (2005)
Variant histone H3.3 is deposited at sites of nucleosomal displacement throughout transcribed genes while active histone modifications show a promoter-proximal bias
C Wirbelauer et al.
GENES & DEVELOPMENT (2005)
The mammalian heterochromatin protein 1 binds diverse nuclear proteins through a common motif that targets the chromoshadow domain
MS Lechner et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2005)
Transcriptional activation triggers deposition and removal of the histone variant H3.3
BE Schwartz et al.
GENES & DEVELOPMENT (2005)
The chromatin-remodeling protein ATRX is critical for neuronal survival during corticogenesis
NG Bérubé et al.
JOURNAL OF CLINICAL INVESTIGATION (2005)
Heterochromatin and ND10 are cell-cycle regulated and phosphorylation-dependent alternate nuclear sites of the transcription repressor Daxx and SWI/SNF protein ATRX
AM Ishov et al.
JOURNAL OF CELL SCIENCE (2004)
ATRX, a member of the SNF2 family of helicase/ATPases, is required for chromosome alignment and meiotic spindle organization in metaphase II stage mouse oocytes
R De La Fuente et al.
DEVELOPMENTAL BIOLOGY (2004)
A silencing pathway to induce H3-K9 and H4-K20 trimethylation at constitutive heterochromatin
G Schotta et al.
GENES & DEVELOPMENT (2004)
Gene expression profiles at diagnosis in de novo childhood AML patients identify FLT3 mutations with good clinical outcomes
NJ Lacayo et al.
BLOOD (2004)
Heterochromatin and tri-methylated lysine 20 of histone H4 in animals
N Kourmouli et al.
JOURNAL OF CELL SCIENCE (2004)
Telomeric recombination in mismatch repair deficient human colon cancer cells after telomerase inhibition
OE Bechter et al.
CANCER RESEARCH (2004)
A novel transcription regulatory complex containing death domain-associated protein and the ATR-X syndrome protein
J Tang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Chromatin remodeling and neuronal response: multiple signaling pathways induce specific histone H3 modifications and early gene expression in hippocampal neurons
C Crosio et al.
JOURNAL OF CELL SCIENCE (2003)
The ATRX syndrome protein forms a chromatin-remodeling complex with Daxx and localizes in promyelocytic leukemia nuclear bodies
YT Xue et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Identification of acquired somatic mutations in the gene encoding chromatin-remodeling factor ATRX in the α-thalassemia myelodysplasia syndrome (ATMDS)
RJ Gibbons et al.
NATURE GENETICS (2003)
HIRA is critical for a nucleosome assembly pathway independent of DNA synthesis
D Ray-Gallet et al.
MOLECULAR CELL (2002)
Neurodevelopmental defects resulting from ATRX overexpression in transgenic mice
NG Bérubé et al.
HUMAN MOLECULAR GENETICS (2002)
Coexistence of alternative lengthening of telomeres and telomerase in hTERT-transfected GM847 cells
K Perrem et al.
MOLECULAR AND CELLULAR BIOLOGY (2001)
NBS1 and TRF1 colocalize at promyelocytic leukemia bodies during late S/G2 phases in immortalized telomerase-negative cells -: Implication of NBS1 in alternative lengthening of telomeres
GK Wu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Cell cycle-dependent phosphorylation of the ATRX protein correlates with changes in nuclear matrix and chromatin association
NG Bérubé et al.
HUMAN MOLECULAR GENETICS (2000)
Mutations in ATRX, encoding a SWI/SNF-like protein, cause diverse changes in the pattern of DNA methylation
RJ Gibbons et al.
NATURE GENETICS (2000)
Isolation and initial characterization of a novel zinc finger gene, DNMT3L, on 21q22.3, related to the cytosine-5-methyltransferase 3 gene family
U Aapola et al.
GENOMICS (2000)
分享论文
