相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。An accumulation of non-farnesylated prelamin A causes cardiomyopathy but not progeria
Brandon S. J. Davies et al.
HUMAN MOLECULAR GENETICS (2010)
Lamin B Counteracts the Kinesin Eg5 to Restrain Spindle Pole Separation during Spindle Assembly
Benjamin Goodman et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Identification of Novel Peptide Substrates for Protein Farnesyltransferase Reveals Two Substrate Classes with Distinct Sequence Selectivities
James L. Hougland et al.
JOURNAL OF MOLECULAR BIOLOGY (2010)
The Protein Farnesyltransferase Regulates HDAC6 Activity in a Microtubule-dependent Manner
Jun Zhou et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Murine CENP-F Regulates Centrosomal Microtubule Nucleation and Interacts with Hook2 at the Centrosome
Katherine L. Moynihan et al.
MOLECULAR BIOLOGY OF THE CELL (2009)
Increased mechanosensitivity and nuclear stiffness in Hutchinson-Gilford progeria cells: effects of farnesyltransferase inhibitors
Valerie L. R. M. Verstraeten et al.
AGING CELL (2008)
Centrosomal PKCβII and pericentrin are critical for human prostate cancer growth and angiogenesis
Jeewon Kim et al.
CANCER RESEARCH (2008)
Farnesyltransferase inhibitors: A detailed chemical view on an elusive biological problem
Sergio F. Sousa et al.
CURRENT MEDICINAL CHEMISTRY (2008)
Progerin elicits disease phenotypes of progeria in mice whether or not it is farnesylated
Shao H. Yang et al.
JOURNAL OF CLINICAL INVESTIGATION (2008)
Combined treatment with statins and aminobisphosphonates extends longevity in a mouse model of human premature aging
Ignacio Varela et al.
NATURE MEDICINE (2008)
A farnesyltransferase inhibitor prevents both the onset and late progression of cardiovascular disease in a progeria mouse model
Brian C. Capell et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Mutations in the pericentrin (PCNT) gene cause primordial dwarfism
Anita Rauch et al.
SCIENCE (2008)
Towards complete sets of farnesylated and geranylgeranylated proteins
Sebastian Maurer-Stroh et al.
PLOS COMPUTATIONAL BIOLOGY (2007)
Farnesyl transferase inhibitors impair chromosomal maintenance in cell lines and human tumors by compromising CENP-E and CENP-F function
Katherine Schafer-Hales et al.
MOLECULAR CANCER THERAPEUTICS (2007)
Protein farnesyltransferase inhibitors and progeria
Margarita Meta et al.
TRENDS IN MOLECULAR MEDICINE (2006)
Compound heterozygosity for mutations in LMNA causes a Progeria syndrome without prelamin A accumulation
Valerie L. R. M. Verstraeten et al.
HUMAN MOLECULAR GENETICS (2006)
A farnesyltransferase inhibitor improves disease phenotypes in mice with a Hutchinson-Gilford progeria syndrome mutation
Shao H. Yang et al.
JOURNAL OF CLINICAL INVESTIGATION (2006)
A mitotic lamin B matrix induced by RanGTP required for spindle assembly
MY Tsai et al.
SCIENCE (2006)
A protein farnesyltransferase inhibitor ameliorates disease in a mouse model of progeria
LG Fong et al.
SCIENCE (2006)
Prelamin A and lamin A appear to be dispensable in the nuclear lamina
LG Fong et al.
JOURNAL OF CLINICAL INVESTIGATION (2006)
Farnesyl and geranylgeranyl transferase inhibitors induce G1 arrest by targeting the proteasome
ET Efuet et al.
CANCER RESEARCH (2006)
Incomplete processing of mutant lamin A in Hutchinson-Gilford progeria leads to nuclear abnormalities, which are reversed by farnesyltransferase inhibition
MW Glynn et al.
HUMAN MOLECULAR GENETICS (2005)
Blocking protein farnesyltransferase improves nuclear shape in fibroblasts from humans with progeroid syndromes
JI Toth et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Targeting ras signalling pathways in cancer therapy
J Downward
NATURE REVIEWS CANCER (2003)
Ras family signaling - Therapeutic targeting
AD Cox et al.
CANCER BIOLOGY & THERAPY (2002)
Unstable kinetochore-microtubule capture and chromosomal instability following deletion of CENP-E
FR Putkey et al.
DEVELOPMENTAL CELL (2002)
The farnesyltransferase inhibitor, FTI-2153, inhibits bipolar spindle formation during mitosis independently of transformation and Ras and p53 mutation status
NC Crespo et al.
CELL DEATH AND DIFFERENTIATION (2002)
Pharmacokinetics of lovastatin extended-release dosage form (lovastatin XL) in healthy volunteers
M Lamson et al.
BIOPHARMACEUTICS & DRUG DISPOSITION (2002)
The farnesyltransferase inhibitor, FTI-2153, blocks bipolar spindle formation and chromosome alignment and causes prometaphase accumulation during mitosis of human lung cancer cells
NC Crespo et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Farnesyl transferase inhibitors block the farnesylation of CENP-E and CENP-F and alter the association of CENP-E with the microtubules
HR Ashar et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
分享论文
