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Chi Kwan Tsang et al.
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Requirement of the mTOR Kinase for the Regulation of Maf1 Phosphorylation and Control of RNA Polymerase III-dependent Transcription in Cancer Cells
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Dr1 (NC2) is present at tRNA genes and represses their transcription in human cells
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BIOCHEMICAL SOCIETY TRANSACTIONS (2009)
Sch9 partially mediates TORC1 signaling to control ribosomal RNA synthesis
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Characterization of the rapamycin-sensitive phosphoproteome reveals that Sch9 is a central coordinator of protein synthesis
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Regulation of RNA Polymerase III Transcription Involves SCH9-dependent and SCH9-independent Branches of the Target of Rapamycin (TOR) Pathway
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被撤回的出版物: Elevated tRNAiMet synthesis can drive cell proliferation and oncogenic transformation (Retracted article. See vol. 151, pg. 455, 2012)
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CELL (2008)
Analysis of the regulatory motifs in eukaryotic initiation factor 4E-binding protein 1
Vivian H. Y. Lee et al.
FEBS JOURNAL (2008)
Derepression of RNA polymerase III transcription by phosphorylation and nuclear export of its negative regulator, Maf1
Joanna Towpik et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Regulation of RNA polymerase III transcription by Maf1 in mammalian cells
Sarah J. Goodfellow et al.
JOURNAL OF MOLECULAR BIOLOGY (2008)
PTEN represses RNA polymerase III-dependent transcription by targeting the TFIIIB complex
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The splicing factor SF2/ASF regulates translation initiation by enhancing phosphorylation of 4E-BP1
Gracjan Michlewski et al.
MOLECULAR CELL (2008)
mTOR controls mitochondrial oxidative function through a YY1-PGC-1α transcriptional complex
John T. Cunningham et al.
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ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage
Shuhei Matsuoka et al.
SCIENCE (2007)
Integration of nutritional and stress signaling pathways by Maf1
Ian M. Willis et al.
TRENDS IN BIOCHEMICAL SCIENCES (2007)
Direct observation of individual endogenous protein complexes in situ by proximity ligation
Ola Soderberg et al.
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Protein kinase A regulates RNA polymerase III transcription through the nuclear localization of Maf1
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Ribosome biogenesis and cell growth: mTOR coordinates transcription by all three classes of nuclear RNA polymerases
C. Mayer et al.
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MTOR, translation initiation and cancer
Y. Mamane et al.
ONCOGENE (2006)
Nutrient regulates Tor1 nuclear localization and association with rDNA promoter
Hong Li et al.
NATURE (2006)
General repression of RNA polymerase III transcription is triggered by protein phosphatase type 2A-mediated dephosphorylation of Maf1
Danuta Oficjalska-Pham et al.
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Dephosphorylation and genome-wide association of Maf1 with Pol III-transcribed genes during repression
Douglas N. Roberts et al.
MOLECULAR CELL (2006)
TOR signaling in growth and metabolism
S Wullschleger et al.
CELL (2006)
TOR signaling in growth and metabolism
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CELL (2006)
Growing roles for the mTOR pathway
DD Sarbassov et al.
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TOR regulates ribosomal protein gene expression via PKA and the forkhead transcription factor FHL1
DE Martin et al.
CELL (2004)
Balancing Akt with S6K: implications for both metabolic diseases and tumorigenesis
BD Manning
JOURNAL OF CELL BIOLOGY (2004)
A dynamic transcriptional network communicates growth potential to ribosome synthesis and critical cell size
P Jorgensen et al.
GENES & DEVELOPMENT (2004)
Two motifs in the translational repressor PHAS-I required for efficient phosphorylation by mammalian target of rapamycin and for recognition by raptor
KM Choi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
TOS motif-mediated raptor binding regulates 4E-BP1 multisite phosphorylation and function
SS Schaim et al.
CURRENT BIOLOGY (2003)
The mammalian target of rapamycin (mTOR) partner, raptor, binds the mTOR substrates p70 S6 kinase and 4E-BP1 through their TOR signaling (TOS) motif
H Nojima et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Maf1 is an essential mediator of diverse signals that repress RNA polymerase III transcription
R Upadhya et al.
MOLECULAR CELL (2002)
Raptor, a binding partner of target of rapamycin (TOR), mediates TOR action
K Hara et al.
CELL (2002)
MTOR interacts with Raptor to form a nutrient-sensitive complex that signals to the cell growth machinery
DH Kim et al.
CELL (2002)
Protein detection using proximity-dependent DNA ligation assays
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NATURE BIOTECHNOLOGY (2002)
Identification of a conserved motif required for mTOR signaling
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