相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Multidrug Resistance in Bacteria
Hiroshi Nikaido
ANNUAL REVIEW OF BIOCHEMISTRY (2009)
Site-Directed Mutagenesis Reveals Amino Acid Residues in the Escherichia coli RND Efflux Pump AcrB That Confer Macrolide Resistance
Caroline Wehmeier et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2009)
Mechanisms of RND multidrug efflux pumps
Hiroshi Nikaido et al.
BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS (2009)
Covalently Linked Trimer of the AcrB Multidrug Efflux Pump Provides Support for the Functional Rotating Mechanism
Yumiko Takatsuka et al.
JOURNAL OF BACTERIOLOGY (2009)
A coordinated network of transporters with overlapping specificities provides a robust survival strategy
Nir Tal et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Kinetic behavior of the major multidrug efflux pump AcrB of Escherichia coli
Keiji Nagano et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Site-Directed Mutagenesis Reveals Putative Substrate Binding Residues in the Escherichia coli RND Efflux Pump AcrB
Juergen A. Bohnert et al.
JOURNAL OF BACTERIOLOGY (2008)
Engineered disulfide bonds support the functional rotation mechanism of multidrug efflux pump AcrB
Markus A. Seeger et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2008)
Site-directed disulfide cross-linking shows that cleft flexibility in the periplasmic domain is needed for the multidrug efflux pump AcrB of Eschetichia coli
Yumiko Takatsuka et al.
JOURNAL OF BACTERIOLOGY (2007)
Drug export pathway of multidrug exporter AcrB revealed by DARPin inhibitors
Gaby Sennhauser et al.
PLOS BIOLOGY (2007)
Threonine-978 in the transmembrane segment of the multidrug efflux pump AcrB of Escherichia coli is crucial for drug transport as a probable component of the proton relay network
Yumiko Takatsuka et al.
JOURNAL OF BACTERIOLOGY (2006)
Conformation of the AcrB multidrug efflux pump in mutants of the putative proton relay pathway
Chih-Chia Su et al.
JOURNAL OF BACTERIOLOGY (2006)
Crystal structures of a multidrug transporter reveal a functionally rotating mechanism
Satoshi Murakami et al.
NATURE (2006)
Structural asymmetry of AcrB trimer suggests a peristaltic pump mechanism
Markus A. Seeger et al.
SCIENCE (2006)
A periplasmic drug-binding site of the AcrB multidrug efflux pump: a crystallographic and site-directed mutagenesis study
EW Yu et al.
JOURNAL OF BACTERIOLOGY (2005)
Selected arylpiperazines are capable of reversing multidrug resistance in Escherichia coli overexpressing RND efflux pumps
HA Bohnert et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2005)
Structural mechanism of the simultaneous binding of two drugs to a multidrug-binding protein
MA Schumacher et al.
EMBO JOURNAL (2004)
Structural basis of multiple drug-binding capacity of the AcrB multidrug efflux pump
EW Yu et al.
SCIENCE (2003)
Structure validation by Cα geometry:: φ,ψ and Cβ deviation
SC Lovell et al.
PROTEINS-STRUCTURE FUNCTION AND GENETICS (2003)
On the mechanism of substrate specificity by resistance nodulation division (RND)-type multidrug resistance pumps:: the large periplasmic loops of MexD from Pseudomonas aeruginosa are involved in substrate recognition
WM Mao et al.
MOLECULAR MICROBIOLOGY (2002)
Crystal structure of bacterial multidrug efflux transporter AcrB
S Murakami et al.
NATURE (2002)
The BaeSR two-component regulatory system activates transcription of the yegMNOB (mdtABCD) transporter gene cluster in Escherichia coli and increases its resistance to novobiocin and deoxycholate
N Baranova et al.
JOURNAL OF BACTERIOLOGY (2002)
The putative response regulator BaeR stimulates multidrug resistance of Escherichia coli via a novel multidrug exporter system, MdtABC
S Nagakubo et al.
JOURNAL OF BACTERIOLOGY (2002)
Mystery of multidrug transporters: the answer can be simple
AA Neyfakh
MOLECULAR MICROBIOLOGY (2002)
Identification and characterization of inhibitors of multidrug resistance efflux pumps in Pseudomonas aeruginosa: Novel agents for combination therapy
O Lomovskaya et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2001)
Entry into and release of solvents by Escherichia coli in an organic-aqueous two-liquid-phase system and substrate specificity of the AcrAB-TolC solvent-extruding pump
N Tsukagoshi et al.
JOURNAL OF BACTERIOLOGY (2000)