期刊
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
卷 107, 期 27, 页码 12086-12090出版社
NATL ACAD SCIENCES
DOI: 10.1073/pnas.1002849107
关键词
biosensing; colorimetric fingerprint; deterministic aperiodic system; nanophotonics
资金
- U.S. Army Research Laboratory
- U.S. Army Research Office [W911 NF-07-1-0618]
- Defense Advanced Research Planning Agency-Defense Sciences Office (DARPA-DSO) [FA9550-10-1-0019]
- Directorate For Engineering
- Div Of Electrical, Commun & Cyber Sys [846651] Funding Source: National Science Foundation
Light scattering phenomena in periodic systems have been investigated for decades in optics and photonics. Their classical description relies on Bragg scattering, which gives rise to constructive interference at specific wavelengths along well defined propagation directions, depending on illumination conditions, structural periodicity, and the refractive index of the surrounding medium. In this paper, by engineering multifrequency colorimetric responses in deterministic aperiodic arrays of nanoparticles, we demonstrate significantly enhanced sensitivity to the presence of a single protein monolayer. These structures, which can be readily fabricated by conventional Electron Beam Lithography, sustain highly complex structural resonances that enable a unique optical sensing approach beyond the traditional Bragg scattering with periodic structures. By combining conventional dark-field scattering micro-spectroscopy and simple image correlation analysis, we experimentally demonstrate that deterministic aperiodic surfaces with engineered structural color are capable of detecting, in the visible spectral range, protein layers with thickness of a few tens of Angstroms.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据