相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Notch1 Functions as a Tumor Suppressor in a Model of K-ras-Induced Pancreatic Ductal Adenocarcinoma
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CANCER RESEARCH (2010)
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Isolation and characterization of centroacinar/terminal ductal progenitor cells in adult mouse pancreas
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Acquisition of Epithelial-Mesenchymal Transition Phenotype of Gemcitabine-Resistant Pancreatic Cancer Cells Is Linked with Activation of the Notch Signaling Pathway
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ELECTROPHORESIS (2009)
Pancreatic Inactivation of c-Myc Decreases Acinar Mass and Transdifferentiates Acinar Cells Into Adipocytes in Mice
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GASTROENTEROLOGY (2009)
Inhibition of γ-Secretase Activity Inhibits Tumor Progression in a Mouse Model of Pancreatic Ductal Adenocarcinoma
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PI3K Signaling Maintains c-myc Expression to Regulate Transcription of E2F1 in Pancreatic Cancer Cells
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p21CIP1 attenuates Ras- and c-Myc-dependent breast tumor epithelial mesenchymal transition and cancer stem cell-like gene expression in vivo
Manran Liu et al.
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Conditional ablation of Notch signaling in pancreatic development
Hassan Nakhai et al.
DEVELOPMENT (2008)
Conditional inactivation of Myc impairs development of the exocrine pancreas
Hassan Nakhai et al.
DEVELOPMENT (2008)
Notch and Kras reprogram pancreatic acinar cells to ductal intraepithelial neoplasia
De La O. Jean-Paul et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Spontaneous induction of murine pancreatic intraepithelial neoplasia (mPanIN) by acinar cell targeting of oncogenic Kras in adult mice
Nils Habbe et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Notch signaling mediates hypoxia-induced tumor cell migration and invasion
Cecilia Sahlgren et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Common Activation of Canonical Wnt Signaling in Pancreatic Adenocarcinoma
Marina Pasca di Magliano et al.
PLOS ONE (2007)
Concomitant pancreatic activation of KrasG12D and Tgfa results in cystic papillary neoplasms reminiscent of human IPMN
Jens T. Siveke et al.
CANCER CELL (2007)
Unique mechanisms of growth regulation and tumor suppression upon Apc inactivation in the pancreas
Alessandra Strom et al.
DEVELOPMENT (2007)
Acinar cells contribute to the molecular heterogeneity of pancreatic intraepithelial neoplasia
Liqin Zhu et al.
AMERICAN JOURNAL OF PATHOLOGY (2007)
Ptf1a is essential for the differentiation of GABAergic and glycinergic amacrine cells and horizontal cells in the mouse retina
Hassan Nakhai et al.
DEVELOPMENT (2007)
Chronic pancreatitis is essential for induction of pancreatic ductal adenocarcinorna by k-Ras Oncogenes in adult mice
Carmen Guerra et al.
CANCER CELL (2007)
Hierarchy of Notch-Delta interactions promoting T cell lineage commitment and maturation
Valerie Besseyrias et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2007)
NOTCH1 directly regulates c-MYC and activates a feed-forward-loop transcriptional network promoting leukemic cell growth
Teresa Palomero et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Aggressive pancreatic ductal adenocarcinoma in mice caused by pancreas-specific blockade of transforming growth factor-β signaling in cooperation with active Kras expression
Hideaki Ijichi et al.
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Hedgehog/Ras interactions regulate early stages of pancreatic cancer
Marina Pasca di Magliano et al.
GENES & DEVELOPMENT (2006)
Notch1 contributes to mouse T-cell leukemia by directly inducing the expression of c-myc
Vishva Mitra Sharma et al.
MOLECULAR AND CELLULAR BIOLOGY (2006)
Expression of the notch signaling pathway and effect on exocrine cell proliferation in adult rat pancreas
Ilse Rooman et al.
AMERICAN JOURNAL OF PATHOLOGY (2006)
c-Myc is an important direct target of Notch1 in T-cell acute lymphoblastic leukemia/lymphoma
Andrew P. Weng et al.
GENES & DEVELOPMENT (2006)
Myc is a Notch1 transcriptional target and a requisite for Notch1-induced mammary tumorigenesis in mice
Apostolos Klinakis et al.
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Genetics and biology of pancreatic ductal adenocarcinoma
Aram F. Hezel et al.
GENES & DEVELOPMENT (2006)
Both p16Ink4a and the p19Arf-p53 pathway constrain progression of pancreatic adenocarcinoma in the mouse
N Bardeesy et al.
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Pten constrains centroacinar cell expansion and malignant transformation in the pancreas
BZ Stanger et al.
CANCER CELL (2005)
Notch2-positive progenitors with the intrinsic ability to give rise to pancreatic ductal cells
KM Lee et al.
LABORATORY INVESTIGATION (2005)
Integration of TGF-β/Smad and Jagged1/Notch signalling in epithelial-to-mesenchymal transition
J Zavadil et al.
EMBO JOURNAL (2004)
Notch promotes epithelial-mesenchymal transition during cardiac development and oncogenic transformation
LA Timmerman et al.
GENES & DEVELOPMENT (2004)
Preinvasive and invasive ductal pancreatic cancer and its early detection in the mouse
SR Hingorani et al.
CANCER CELL (2003)
Hedgehog is an early and late mediator of pancreatic cancer tumorigenesis
SP Thayer et al.
NATURE (2003)
Murine pancreatic tumor cell line TD2 bears the characteristic pattern of genetic changes with two independently amplified gene loci
B Schreiner et al.
ONCOGENE (2003)
Notch mediates TGFα-induced changes in epithelial differentiation during pancreatic tumorigenesis
Y Miyamoto et al.
CANCER CELL (2003)
c-MYC activation in primary and metastatic ductal adenocarcinoma of the pancreas: Incidence, mechanisms, and clinical significance
C Schleger et al.
MODERN PATHOLOGY (2002)
Notch signaling is a direct determinant of keratinocyte growth arrest and entry into differentiation
A Rangarajan et al.
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