4.8 Article Retracted Publication

被撤回的出版物: Phospholipid bilayers are viscoelastic (Retracted article. See vol. 108, pg. 14705, 2011)

出版社

NATL ACAD SCIENCES
DOI: 10.1073/pnas.1010700107

关键词

complex fluids; biomaterials; soft condensed matter

资金

  1. Alfred P. Sloan Foundation
  2. Office of Naval Research through the Oregon Nanoscience and Microtechnologies Institute
  3. National Science Foundation [1006171, 0742540, 0622620]
  4. Direct For Education and Human Resources
  5. Division Of Graduate Education [0742540] Funding Source: National Science Foundation
  6. Direct For Education and Human Resources
  7. Division Of Undergraduate Education [0622620] Funding Source: National Science Foundation
  8. Division Of Materials Research
  9. Direct For Mathematical & Physical Scien [1006171] Funding Source: National Science Foundation

向作者/读者索取更多资源

Lipid bilayers provide the structural framework for cellular membranes, and their character as two-dimensional fluids enables the mobility of membrane macromolecules. Though the existence of membrane fluidity is well established, the nature of this fluidity remains poorly characterized. Three-dimensional fluids as diverse as chocolates and cytoskeletal networks show a rich variety of Newtonian and non-Newtonian dynamics that have been illuminated by contemporary rheological techniques. Applying particle-tracking microrheology to freestanding phospholipid bilayers, we find that the membranes are not simply viscous but rather exhibit viscoelasticity, with an elastic modulus that dominates the response above a characteristic frequency that diverges at the fluid-gel (L(alpha) - L(beta)) phase-transition temperature. These findings fundamentally alter our picture of the nature of lipid bilayers and the mechanics of membrane environments.

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