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Silvia Fre et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Impaired embryonic haematopoiesis yet normal arterial development in the absence of the Notch ligand Jagged1
Alex Robert-Moreno et al.
EMBO JOURNAL (2008)
Loss of intestinal crypt progenitor cells owing to inactivation of both Notch1 and Notch2 is accompanied by derepression of CDK inhibitors p27Kip1 and p57Kip2
Orbicia Riccio et al.
EMBO REPORTS (2008)
Kruppel-like factor 5 mediates cellular transformation during oncogenic KRAS-induced intestinal tumorigenesis
Mandayam O. Nandan et al.
GASTROENTEROLOGY (2008)
Nox1 is over-expressed in human colon cancers and correlates with activating mutations in K-Ras
Eunice Laurent et al.
INTERNATIONAL JOURNAL OF CANCER (2008)
Jagged1-mediated Notch activation induces epithelial-to-mesenchymal transition through Slug-induced repression of E-cadherin
Kevin G. Leong et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2007)
Mastermind-like 1 is a specific coactivator of β-catenin transcription activation and is essential for colon carcinoma cell survival
Marie-Clotilde Alves-Guerra et al.
CANCER RESEARCH (2007)
Sox9 regulates cell proliferation and is required for Paneth cell differentiation in the intestinal epithelium
Pauline Bastide et al.
JOURNAL OF CELL BIOLOGY (2007)
Phenotypic characterization of human colorectal cancer stem cells
Piero Dalerba et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Myc deletion rescues Apc deficiency in the small intestine
Owen J. Sansom et al.
NATURE (2007)
Nuclear IKK activity leads to dysregulated Notch-dependent gene expression in colorectal cancer
V. Fernandez-Majada et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
NOTCH1 directly regulates c-MYC and activates a feed-forward-loop transcriptional network promoting leukemic cell growth
Teresa Palomero et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Jagged 1 is a β-catenin target gene required for ectopic hair follicle formation in adult epidermis
Soline Estrach et al.
DEVELOPMENT (2006)
Notch synergizes with axin to regulate the activity of armadillo in Drosophila
Penelope Hayward et al.
DEVELOPMENTAL DYNAMICS (2006)
c-Myc is an important direct target of Notch1 in T-cell acute lymphoblastic leukemia/lymphoma
Andrew P. Weng et al.
GENES & DEVELOPMENT (2006)
Activation of Notch1 signaling is required for β-catenin-mediated human primary melanoma progression
K Balint et al.
JOURNAL OF CLINICAL INVESTIGATION (2005)
Expression of NOX1, a superoxide-generating NADPH oxidase, in colon cancer and inflammatory bowel disease
I Szanto et al.
JOURNAL OF PATHOLOGY (2005)
EphB receptor activity suppresses colorectal cancer progression
E Batlle et al.
NATURE (2005)
Notch signals control the fate of immature progenitor cells in the intestine
S Fre et al.
NATURE (2005)
Notch/γ-secretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells
JH van Es et al.
NATURE (2005)
Meningioma transcript profiles reveal deregulated notch signaling pathway
IC Cuevas et al.
CANCER RESEARCH (2005)
Hes1-deficient mice show precocious differentiation of Paneth cells in the small intestine
K Suzuki et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2005)
Notch signaling: control of cell communication and cell fate
EC Lai
DEVELOPMENT (2004)
The Bmi-1 oncoprotein is overexpressed in human colorectal cancer and correlates with the reduced p16INK4a/p14ARF proteins
JH Kim et al.
CANCER LETTERS (2004)
SOX9 is an intestine crypt transcription factor, is regulated by the Wnt pathway, and represses the CDX2 and MUC2 genes
P Blache et al.
JOURNAL OF CELL BIOLOGY (2004)
Recruitment of IκBα to the hes1 promoter is associated with transcriptional repression
C Aguilera et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Notch1 and Notch2 have opposite effects on embryonal brain tumor growth
X Fan et al.
CANCER RESEARCH (2004)
Small-molecule antagonists of the oncogenic Tcf/beta-catenin protein complex
M Lepourcelet et al.
CANCER CELL (2004)
Wingless and Notch signaling provide cell survival cues and control cell proliferation during wing development
AJ Giraldez et al.
DEVELOPMENT (2003)
Phosphorylation by glycogen synthase kinase-3β down-regulates Notch activity, a link for Notch and Wnt pathways
L Espinosa et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
β-catenin and TCF mediate cell positioning in the intestinal epithelium by controlling the expression of EphB/EphrinB
E Batlle et al.
CELL (2002)
The β-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells
M van de Wetering et al.
CELL (2002)
Fringe differentially modulates Jagged1 and Delta1 signalling through Notch1 and Notch2
C Hicks et al.
NATURE CELL BIOLOGY (2000)
A ligand-induced extracellular cleavage regulates γ-secretase-like proteolytic activation of Notch1
JS Mumm et al.
MOLECULAR CELL (2000)
Control sf endodermal endocrine development by Hes-1
J Jensen et al.
NATURE GENETICS (2000)
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