相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。The peroxisome proliferators activated receptor-gamma agonists as therapeutics for the treatment of Alzheimer's disease and mild-to-moderate Alzheimer's disease: a meta-analysis
Huawei Cheng et al.
INTERNATIONAL JOURNAL OF NEUROSCIENCE (2016)
Rosiglitazone Improves Learning and Memory Ability in Rats With Type 2 Diabetes Through the Insulin Signaling Pathway
Lina Ma et al.
AMERICAN JOURNAL OF THE MEDICAL SCIENCES (2015)
Effect of pioglitazone medication on the incidence of dementia
Michael T. Heneka et al.
ANNALS OF NEUROLOGY (2015)
Advances in Alzheimer's Disease Drug Development
Michael S. Rafii et al.
BMC MEDICINE (2015)
Current Practices in the Treatment of Alzheimer Disease: Where is the Evidence After the Phase III Trials?
Megan J. Ehret et al.
CLINICAL THERAPEUTICS (2015)
Nuclear Receptors License Phagocytosis by Trem2+ Myeloid Cells in Mouse Models of Alzheimer's Disease
Julie C. Savage et al.
JOURNAL OF NEUROSCIENCE (2015)
Amyloid cascade hypothesis: Pathogenesis and therapeutic strategies in Alzheimer's disease
Sagar H. Barage et al.
NEUROPEPTIDES (2015)
Mitochondrial Dysfunction Contributes to the Pathogenesis of Alzheimer's Disease
Fabian A. Cabezas-Opazo et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2015)
Aberrant insulin signaling in Alzheimer's disease: current knowledge
Gaurav Bedse et al.
FRONTIERS IN NEUROSCIENCE (2015)
Insulin sensitizers improve learning and attenuate tau hyperphosphorylation and neuroinflammation in 3xTg-AD mice
Yang Yu et al.
JOURNAL OF NEURAL TRANSMISSION (2015)
Anti-Diabetes Drug Pioglitazone Ameliorates Synaptic Defects in AD Transgenic Mice by Inhibiting Cyclin-Dependent Kinase5 Activity
Jinan Chen et al.
PLOS ONE (2015)
Inflammation, Defective Insulin Signaling, and Mitochondrial Dysfunction as Common Molecular Denominators Connecting Type 2 Diabetes to Alzheimer Disease
Fernanda G. De Felice et al.
DIABETES (2014)
Mitochondrial target of thiazolidinediones
J. R. Colca et al.
DIABETES OBESITY & METABOLISM (2014)
Suppression of neuroinflammation in forebrain-specific Cdk5 conditional knockout mice by PPARγ agonist improves neuronal loss and early lethality
Elias Utreras et al.
JOURNAL OF NEUROINFLAMMATION (2014)
PPARγ Recruitment to Active ERK during Memory Consolidation Is Required for Alzheimer's Disease-Related Cognitive Enhancement
Jordan B. Jahrling et al.
JOURNAL OF NEUROSCIENCE (2014)
Rosiglitazone promotes neurite outgrowth and mitochondrial function in N2A cells via PPARgamma pathway
Ming-Chang Chiang et al.
MITOCHONDRION (2014)
Animal models of dementia and cognitive dysfunction
Neha et al.
LIFE SCIENCES (2014)
Dynamic changes in pro- and anti-inflammatory cytokines in microglia after PPAR-γ agonist neuroprotective treatment in the MPTPp mouse model of progressive Parkinson's disease
Augusta Pisanu et al.
NEUROBIOLOGY OF DISEASE (2014)
Rosiglitazone prevents the memory deficits induced by amyloid-beta oligomers via inhibition of inflammatory responses
Shujun Xu et al.
NEUROSCIENCE LETTERS (2014)
Role of Nuclear Receptor on Regulation of BDNF and Neuroinflammation in Hippocampus of β-Amyloid Animal Model of Alzheimer's Disease
Atish Prakash et al.
NEUROTOXICITY RESEARCH (2014)
Is Alzheimer's disease related to metabolic syndrome? A Wnt signaling conundrum
Juvenal A. Rios et al.
PROGRESS IN NEUROBIOLOGY (2014)
Cyclin-dependent kinase 5, a node protein in diminished tauopathy: a systems biology approach
John F. Castro-Alvarez et al.
FRONTIERS IN AGING NEUROSCIENCE (2014)
Troglitazone, a thiazolidinedione, decreases tau phosphorylation through the inhibition of cyclin-dependent kinase 5 activity in SH-SY5Y neuroblastoma cells and primary neurons
Du-Hyong Cho et al.
JOURNAL OF NEUROCHEMISTRY (2013)
Peroxisome Proliferator-activated Receptors and Alzheimer's Disease: Hitting the Blood-Brain Barrier
Juan M. Zolezzi et al.
MOLECULAR NEUROBIOLOGY (2013)
Pioglitazone Improves Reversal Learning and Exerts Mixed Cerebrovascular Effects in a Mouse Model of Alzheimer's Disease with Combined Amyloid-beta and Cerebrovascular Pathology
Panayiota Papadopoulos et al.
PLOS ONE (2013)
Identification of 15d-PGJ2 as an antagonist of farnesoid X receptor: Molecular modeling with biological evaluation
Xing Xu et al.
STEROIDS (2013)
The Classification of Microglial Activation Phenotypes on Neurodegeneration and Regeneration in Alzheimer's Disease Brain
Megan M. Varnum et al.
ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS (2012)
Alzheimer Mechanisms and Therapeutic Strategies
Yadong Huang et al.
CELL (2012)
Long-Term Pioglitazone Treatment Improves Learning and Attenuates Pathological Markers in a Mouse Model of Alzheimer's Disease
James L. Searcy et al.
JOURNAL OF ALZHEIMERS DISEASE (2012)
Rosiglitazone Improves Spatial Memory and Decreases Insoluble Aβ1-42 in APP/PS1 Mice
Julie-Ann O'Reilly et al.
JOURNAL OF NEUROIMMUNE PHARMACOLOGY (2012)
PPARγ/RXRα-Induced and CD36-Mediated Microglial Amyloid-β Phagocytosis Results in Cognitive Improvement in Amyloid Precursor Protein/Presenilin 1 Mice
Mitsugu Yamanaka et al.
JOURNAL OF NEUROSCIENCE (2012)
Mechanisms Underlying the Rapid Peroxisome Proliferator-Activated Receptor-γ-Mediated Amyloid Clearance and Reversal of Cognitive Deficits in a Murine Model of Alzheimer's Disease
Shweta Mandrekar-Colucci et al.
JOURNAL OF NEUROSCIENCE (2012)
PPAR? agonist pioglitazone improves scopolamine-induced memory impairment in mice
Guo Qing Xiang et al.
JOURNAL OF PHARMACY AND PHARMACOLOGY (2012)
Metformin, Other Antidiabetic Drugs, and Risk of Alzheimer's Disease: A Population-Based Case-Control Study
Patrick Imfeld et al.
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY (2012)
The ε3 and ε4 Alleles of Human APOE Differentially Affect Tau Phosphorylation in Hyperinsulinemic and Pioglitazone Treated Mice
Alvina W. M. To et al.
PLOS ONE (2011)
Human apoE Isoforms Differentially Regulate Brain Amyloid-β Peptide Clearance
Joseph M. Castellano et al.
SCIENCE TRANSLATIONAL MEDICINE (2011)
Activation of Wnt signaling by lithium and rosiglitazone reduced spatial memory impairment and neurodegeneration in brains of an APPswe/PSEN1ΔE9 mouse model of Alzheimer's disease
E. M. Toledo et al.
MOLECULAR PSYCHIATRY (2010)
Rosiglitazone reduces tau phosphorylation via JNK inhibition in the hippocampus of rats with type 2 diabetes and tau transfected SH-SY5Y cells
Seung-Yong Yoon et al.
NEUROBIOLOGY OF DISEASE (2010)
The Genetics of Alzheimer Disease: Back to the Future
Lars Bertram et al.
NEURON (2010)
Rosiglitazone Rescues Memory Impairment in Alzheimer's Transgenic Mice: Mechanisms Involving a Reduced Amyloid and Tau Pathology
Luis Escribano et al.
NEUROPSYCHOPHARMACOLOGY (2010)
MECHANISMS OF DISEASE Alzheimer's Disease
Henry W. Querfurth et al.
NEW ENGLAND JOURNAL OF MEDICINE (2010)
Decreased Clearance of CNS β-Amyloid in Alzheimer's Disease
Kwasi G. Mawuenyega et al.
SCIENCE (2010)
Immune Activation in Brain Aging and Neurodegeneration: Too Much or Too Little?
Kurt M. Lucin et al.
NEURON (2009)
S-Nitrosylation of Drp1 Mediates β-Amyloid-Related Mitochondrial Fission and Neuronal Injury
Dong-Hyung Cho et al.
SCIENCE (2009)
Molecular basis of selective PPARγ modulation for the treatment of type 2 diabetes
Laurent Gelman et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS (2007)
How common are the common neurologic disorders?
D. Hirtz et al.
NEUROLOGY (2007)
The metabolic syndrome and Alzheimer disease
George Razay et al.
ARCHIVES OF NEUROLOGY (2007)
Drug Insight: effects mediated by peroxisome proliferator-activated receptor-gamma in CNS disorders
Michael T. Heneka et al.
NATURE CLINICAL PRACTICE NEUROLOGY (2007)
Association of metabolic syndrome with Alzheimer disease : A population-based study
M. Vanhanen et al.
NEUROLOGY (2006)
Troglitazone, a peroxisome proliferator-activated receptor-γ agonist, decreases tau phosphorylation in CHOtau4R cells
Cristina d'Abramo et al.
JOURNAL OF NEUROCHEMISTRY (2006)
Efficacy of rosiglitazone in a genetically defined population with mild-to-moderate Alzheimer's disease
M. E. Risner et al.
PHARMACOGENOMICS JOURNAL (2006)
Transcriptional regulation of metabolism
B Desvergne et al.
PHYSIOLOGICAL REVIEWS (2006)
Acute treatment with the PPARγ agonist pioglitazone and ibuprofen reduces glial inflammation and Aβ1-42 levels in APPV717I transgenic mice
MT Heneka et al.
BRAIN (2005)
Axonal transport defects: a common theme in neurodegenerative diseases
S Roy et al.
ACTA NEUROPATHOLOGICA (2005)
Interleukin-6 induces Alzheimer-type phosphorylation of tau protein by deregulating the cdk5/p35 pathway
RA Quintanilla et al.
EXPERIMENTAL CELL RESEARCH (2004)
Regulation of β-amyloid stimulated proinflammatory responses by peroxisome proliferator-activated receptor α
CK Combs et al.
NEUROCHEMISTRY INTERNATIONAL (2001)
分享论文
