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注意:仅列出部分参考文献,下载原文获取全部文献信息。Essential role for nuclear PTEN in maintaining chromosomal integrity
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CELL (2007)
Ubiquitination regulates PTEN nuclear import and tumor suppression
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NEDD4-1 is a proto-oncogenic ubiquitin ligase for PTEN
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Transport of LAPTM5 to lysosomes requires association with the ubiquitin ligase Nedd4, but not LAPTM5 ubiquitination
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PTEN function in normal and neoplastic growth
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The evolution of phosphatidylinositol 3-kinases as regulators of growth and metabolism
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Role of ubiquitylation in cellular membrane transport
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Structural determinants for high-affinity binding in a Nedd4 WW3*domain-Comm PY motif complex
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Nuclear-cytoplasmic partitioning of phosphatase and tensin homologue deleted on chromosome 10 (PTEN) differentially regulates the cell cycle and apoptosis
JH Chung et al.
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Nuclear PTEN-mediated growth suppression is independent of Akt down-regulation
JL Liu et al.
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The RAD51 gene family, genetic instability and cancer
J Thacker
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The Nedd4 family of E3 ubiquitin ligases: functional diversity within a common modular architecture
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Regulation of PTEN phosphorylation and stability by a tumor suppressor candidate protein
F Okahara et al.
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Nedd4.1-mediated ubiquitination and subsequent recruitment of Tsg101 ensure HTLV-1 Gag trafficking towards the multivesicular body pathway prior to virus budding
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SHIP-2 and PTEN are expressed and active in vascular smooth muscle cell nuclei, but only SHIP-2 is associated with nuclear speckles
P Déléris et al.
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Phosphorylation-regulated cleavage of the tumor suppressor PTEN by caspase-3 - Implications for the control of protein stability and PTEN-protein interactions
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JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
The phosphatidylinositol 3-kinase-AKT pathway in human cancer
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NATURE REVIEWS CANCER (2002)
Nuclear PTEN expression and clinicopathologic features in a population-based series of primary cutaneous melanoma
DC Whiteman et al.
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Expression and prognostic significance of PTEN product protein in patients with esophageal squamous cell carcinoma
M Tachibana et al.
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Nedd4 regulates ubiquitination and stability of the guanine-nucleotide exchange factor CNrasGEF
N Pham et al.
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Solution structure of a Nedd4 WW domain-ENaC peptide complex
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Characterizing Class IWW domains defines key specificity determinants and generates mutant domains with novel specificities
J Kasanov et al.
CHEMISTRY & BIOLOGY (2001)
The tumor suppressor PTEN is phosphorylated by the protein kinase CK2 at its C terminus - Implications for PTEN stability to proteasome-mediated degradation
J Torres et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Mutation and expression analyses reveal differential subcellular compartmentalization of PTEN in endocrine pancreatic tumors compared to normal islet cells
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Phosphorylation of the PTEN tail regulates protein stability and function
F Vazquez et al.
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Changes in endometrial PTEN expression throughout the human menstrual cycle
GL Mutter et al.
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Differential nuclear and cytoplasmic expression of PTEN in normal thyroid tissue, and benign and malignant epithelial thyroid tumors
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Inhibition of H-Ras transformation by the PTEN/MMAC1/TEP1 tumor suppressor gene
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ONCOGENE (2000)