期刊
PROCEEDINGS OF THE INSTITUTION OF MECHANICAL ENGINEERS PART H-JOURNAL OF ENGINEERING IN MEDICINE
卷 224, 期 H12, 页码 1329-1343出版社
SAGE PUBLICATIONS LTD
DOI: 10.1243/09544119JEIM770
关键词
bone graft; autograft; allograft; hydroxyapatite; osteolysis; nanotopography; osteoconductive; osteoinductive
As the population ages, the number of operations performed on bone is expected to increase. Diseases such as arthritis, tumours, and trauma can lead to defects in the skeleton requiring an operation to replace or restore the lost bone. Surgeons can use autografts, allografts, and/or bone graft substitutes to restore areas of bone loss. Surgical implants are also used in addition or in isolation to replace the diseased bone. This review considers the application of available bone grafts in different clinical settings. It also discusses recently introduced bioactive biomaterials and highlights the clinical difficulties and technological deficiencies that exist in our current surgical practice.
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