4.7 Article

Inadequate fine-tuning of protein synthesis and failure of amino acid homeostasis following inhibition of the ATPase VCP/p97

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Cell Biology

Structural and Functional Analysis of the GADD34:PP1 eIF2α Phosphatase

Meng S. Choy et al.

CELL REPORTS (2015)

Review Oncology

Endoplasmic Reticulum Stress in Malignancy

Hanna J. Clarke et al.

CANCER CELL (2014)

Article Biochemistry & Molecular Biology

Translational Control during Endoplasmic Reticulum Stress beyond Phosphorylation of the Translation Initiation Factor eIF2α

Bo-Jhih Guan et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2014)

Article Multidisciplinary Sciences

Coordinated regulation of protein synthesis and degradation by mTORC1

Yinan Zhang et al.

NATURE (2014)

Review Biochemistry & Molecular Biology

The eIF2α kinases: their structures and functions

Neysan Donnelly et al.

CELLULAR AND MOLECULAR LIFE SCIENCES (2013)

Article Biochemistry & Molecular Biology

Covalent and allosteric inhibitors of the ATPase VCP/p97 induce cancer cell death

Paola Magnaghi et al.

NATURE CHEMICAL BIOLOGY (2013)

Article Multidisciplinary Sciences

Cdc48-associated complex bound to 60S particles is required for the clearance of aberrant translation products

Quentin Defenouillere et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)

Review Biochemistry & Molecular Biology

mTOR Signaling in Growth Control and Disease

Mathieu Laplante et al.

Article Biochemistry & Molecular Biology

The p97/VCP ATPase is critical in muscle atrophy and the accelerated degradation of muscle proteins

Rosanna Piccirillo et al.

EMBO JOURNAL (2012)

Review Hematology

DangER: protein ovERload. Targeting protein degradation to treat myeloma

Lauren I. Aronson et al.

HAEMATOLOGICA-THE HEMATOLOGY JOURNAL (2012)

Article Biochemistry & Molecular Biology

Failure of Amino Acid Homeostasis Causes Cell Death following Proteasome Inhibition

Amila Suraweera et al.

MOLECULAR CELL (2012)

Review Cell Biology

Emerging functions of the VCP/p97 AAA-ATPase in the ubiquitin system

Hemmo Meyer et al.

NATURE CELL BIOLOGY (2012)

Editorial Material Cell Biology

Development of p97 AAA ATPase inhibitors

Tsui-Fen Chou et al.

AUTOPHAGY (2011)

Review Oncology

Transcriptional Control of Cellular Metabolism by mTOR Signaling

Jessica L. Yecies et al.

CANCER RESEARCH (2011)

Article Medicine, Research & Experimental

Next-generation mTOR inhibitors in clinical oncology: how pathway complexity informs therapeutic strategy

Seth A. Wander et al.

JOURNAL OF CLINICAL INVESTIGATION (2011)

Article Biochemistry & Molecular Biology

Cdc48/p97 Mediates UV-Dependent Turnover of RNA Pol II

Rati Verma et al.

MOLECULAR CELL (2011)

Article Multidisciplinary Sciences

Reversible inhibitor of p97, DBeQ, impairs both ubiquitin-dependent and autophagic protein clearance pathways

Tsui-Fen Chou et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)

Review Multidisciplinary Sciences

The Unfolded Protein Response: From Stress Pathway to Homeostatic Regulation

Peter Walter et al.

SCIENCE (2011)

Article Biochemistry & Molecular Biology

Proteasomal Degradation Is Transcriptionally Controlled by TCF11 via an ERAD-Dependent Feedback Loop

Janos Steffen et al.

MOLECULAR CELL (2010)

Article Biochemical Research Methods

SUnSET, a nonradioactive method to monitor protein synthesis

Enrico K. Schmidt et al.

NATURE METHODS (2009)

Article Biochemistry & Molecular Biology

Impaired Protein Aggregate Handling and Clearance Underlie the Pathogenesis of p97/VCP-associated Disease

Jeong-Sun Ju et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2008)

Article Biochemistry & Molecular Biology

Targeted deletion of p97 (VCP/CDC48) in mouse results in early embryonic lethality

J. M. M. Mueller et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2007)

Article Cell Biology

The ubiquitin-selective chaperone CDC-48/p97 links myosin assembly to human myopathy

Philipp Christoph Janiesch et al.

NATURE CELL BIOLOGY (2007)

Article Multidisciplinary Sciences

Protein synthesis upon acute nutrient restriction relies on proteasome function

RM Vabulas et al.

SCIENCE (2005)

Article Multidisciplinary Sciences

Recruitment of the p97 ATPase and ubiquitin ligases to the site of retrotranslocation at the endoplasmic reticulum membrane

YH Ye et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)

Article Biochemistry & Molecular Biology

The AAA-ATPase Cdc48/p97 regulates spindle disassembly at the end of mitosis

K Cao et al.

Article Biochemistry & Molecular Biology

An integrated stress response regulates amino acid metabolism and resistance to oxidative stress

HP Harding et al.

MOLECULAR CELL (2003)

Article Multidisciplinary Sciences

Functional profiling of the Saccharomyces cerevisiae genome

G Giaever et al.

NATURE (2002)

Article Biochemistry & Molecular Biology

Regulated translation initiation controls stress-induced gene expression in mammalian cells

HP Harding et al.

MOLECULAR CELL (2000)

Article Biochemistry & Molecular Biology

Perk is essential for translational regulation and cell survival during the unfolded protein response

HP Harding et al.

MOLECULAR CELL (2000)