相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Ganetespib and HSP90: Translating Preclinical Hypotheses into Clinical Promise
David A. Proia et al.
CANCER RESEARCH (2014)
Contribution of Aurora-A and -B expression to DNA aneuploidy in gastric cancers
Kenichi Honma et al.
SURGERY TODAY (2014)
The PI3K/AKT/mTOR pathway is activated in gastric cancer with potential prognostic and predictive significance
Oscar Tapia et al.
VIRCHOWS ARCHIV (2014)
Inhibition of gastric tumor growth by a novel Hsp90 inhibitor
Chunwan Lu et al.
BIOCHEMICAL PHARMACOLOGY (2013)
The HSP90 Inhibitor Ganetespib Synergizes with the MET Kinase Inhibitor Crizotinib in both Crizotinib-Sensitive and -Resistant MET-Driven Tumor Models
Naoto Miyajima et al.
CANCER RESEARCH (2013)
Network Analysis Identifies an HSP90-Central Hub Susceptible in Ovarian Cancer
Hanqing Liu et al.
CLINICAL CANCER RESEARCH (2013)
First-in-Human Phase I Dose-Escalation Study of the HSP90 Inhibitor AUY922 in Patients with Advanced Solid Tumors
Cristiana Sessa et al.
CLINICAL CANCER RESEARCH (2013)
Inhibition of HSP90 with AUY922 Induces Synergy in HER2-Amplified Trastuzumab-Resistant Breast and Gastric Cancer
Zev A. Wainberg et al.
MOLECULAR CANCER THERAPEUTICS (2013)
Gastric cancer-molecular and clinical dimensions
Roopma Wadhwa et al.
NATURE REVIEWS CLINICAL ONCOLOGY (2013)
High Expression of Heat Shock Protein 90 Is Associated with Tumor Aggressiveness and Poor Prognosis in Patients with Advanced Gastric Cancer
Jiahong Wang et al.
PLOS ONE (2013)
HSP90 Inhibitors: Current Development and Potential in Cancer Therapy
Katerina Sidera et al.
Recent Patents on Anti-Cancer Drug Discovery (2013)
Recent updates on the development of ganetespib as a Hsp90 inhibitor
Hyun Kyung Choi et al.
ARCHIVES OF PHARMACAL RESEARCH (2012)
Preclinical antitumor activity of the novel heat shock protein 90 inhibitor CH5164840 against human epidermal growth factor receptor 2 (HER2)-overexpressing cancers
Naomi Ono et al.
CANCER SCIENCE (2012)
Combined inhibition of Wee1 and Hsp90 activates intrinsic apoptosis in cancer cells
Aki Iwai et al.
CELL CYCLE (2012)
Hsp90 Molecular Chaperone Inhibitors: Are We There Yet?
Len Neckers et al.
CLINICAL CANCER RESEARCH (2012)
Ganetespib, a Unique Triazolone-Containing Hsp90 Inhibitor, Exhibits Potent Antitumor Activity and a Superior Safety Profile for Cancer Therapy
Weiwen Ying et al.
MOLECULAR CANCER THERAPEUTICS (2012)
The Novel Oral Hsp90 Inhibitor NVP-HSP990 Exhibits Potent and Broad-spectrum Antitumor Activities In Vitro and In Vivo
Daniel L. Menezes et al.
MOLECULAR CANCER THERAPEUTICS (2012)
Heat shock protein 90α (HSP90α), a substrate and chaperone of DNA-PK necessary for the apoptotic response
Stephanie Solier et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Antitumor activity of NVP-AUY922, a novel heat shock protein 90 inhibitor, in human gastric cancer cells is mediated through proteasomal degradation of client proteins
Kyung-Hun Lee et al.
CANCER SCIENCE (2011)
Heat-shock protein 90 inhibitors as antitumor agents: a survey of the literature from 2005 to 2010
Samir Messaoudi et al.
EXPERT OPINION ON THERAPEUTIC PATENTS (2011)
Designed hybrid TPR peptide targeting Hsp90 as a novel anticancer agent
Tomohisa Horibe et al.
JOURNAL OF TRANSLATIONAL MEDICINE (2011)
Efficacy and Safety of Oxaliplatin, 5-Fluorouracil, and Folinic Acid Combination Chemotherapy as First-Line Treatment in Metastatic or Recurrent Gastric Cancer
Han Jo Kim et al.
CANCER RESEARCH AND TREATMENT (2011)
Drug Combination Studies and Their Synergy Quantification Using the Chou-Talalay Method
Ting-Chao Chou
CANCER RESEARCH (2010)
Expression of HSP90 in gastrointestinal stromal tumours and mesenchymal tumours
Gu Hyun Kang et al.
HISTOPATHOLOGY (2010)
Identification of c-Src as a Potential Therapeutic Target for Gastric Cancer and of MET Activation as a Cause of Resistance to c-Src Inhibition
Wataru Okamoto et al.
MOLECULAR CANCER THERAPEUTICS (2010)
Targeting the dynamic HSP90 complex in cancer
Jane Trepel et al.
NATURE REVIEWS CANCER (2010)
Discovery and development of heat shock protein 90 inhibitors
Tony Taldone et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2009)
Src kinases as therapeutic targets for cancer
Lori C. Kim et al.
NATURE REVIEWS CLINICAL ONCOLOGY (2009)
Targeting Hsp90: small-molecule inhibitors and their clinical development
Tony Taldone et al.
CURRENT OPINION IN PHARMACOLOGY (2008)
Development and application of Hsp90 inhibitors
David B. Solit et al.
DRUG DISCOVERY TODAY (2008)
Extracellular heat shock protein 90: A role for a molecular chaperone in cell motility and cancer metastasis
Shinji Tsutsumi et al.
CANCER SCIENCE (2007)
Inhibition of heat shock protein 90 impairs epidermal growth factor-mediated signaling in gastric cancer cells and reduces tumor growth and vascularization in vivo
Sven A. Lang et al.
MOLECULAR CANCER THERAPEUTICS (2007)
Blockage of HSP 90 modulates Helicobacter pylori-induced IL-8 productions through the inactivation of transcriptional factors of AP-1 and NF-KB
M Yeo et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2004)
A high-affinity conformation of Hsp90 confers tumour selectivity on Hsp90 inhibitors
A Kamal et al.
NATURE (2003)
分享论文
