相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。A Noncompetitive Inhibitor for Mycobacterium tuberculosis's Class IIa Fructose 1,6-Bisphosphate Aldolase
Glenn C. Capodagli et al.
BIOCHEMISTRY (2014)
Targeting histone lysine demethylases - Progress, challenges, and the future
Cyrille C. Thinnes et al.
BIOCHIMICA ET BIOPHYSICA ACTA-GENE REGULATORY MECHANISMS (2014)
Design and synthesis of 8-hydroxyquinoline-based radioprotective agents
Shinya Ariyasu et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2014)
Screening and identification of novel compounds with potential anti-proliferative effects on gallium-resistant lung cancer through an AXL kinase pathway
Moses O. Oyewumi et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2014)
A Cell-Permeable Ester Derivative of the JmjC Histone Demethylase Inhibitor IOX1
Rachel Schiller et al.
CHEMMEDCHEM (2014)
Old Friends in New Guise: Exploiting Privileged Structures for Scaffold Re-Evolution/Refining
Yu'ning Song et al.
COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING (2014)
Donepezil plus propargylamine+8-hydroxyquinoline hybrids as new multifunctional metal-chelators, ChE and MAO inhibitors for the potential treatment of Alzheimer's disease
Li Wang et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2014)
Synthesis and antiproliferative activity of 8-hydroxyquinoline derivatives containing a 1,2,3-triazole moiety
Luiza B. de O. Freitas et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2014)
Pan-Histone Demethylase Inhibitors Simultaneously Targeting Jumonji C and Lysine-Specific Demethylases Display High Anticancer Activities
Dante Rotili et al.
JOURNAL OF MEDICINAL CHEMISTRY (2014)
Identification of Clinically Viable Quinolinol Inhibitors of Botulinum Neurotoxin A Light Chain
Dejan Caglic et al.
JOURNAL OF MEDICINAL CHEMISTRY (2014)
Therapeutics of Alzheimer's disease: Past, present and future
R. Anand et al.
NEUROPHARMACOLOGY (2014)
New multi-target-directed small molecules against Alzheimer's disease: a combination of resveratrol and clioquinol
Fei Mao et al.
ORGANIC & BIOMOLECULAR CHEMISTRY (2014)
Hydroxyquinoline-derived compounds and analoguing of selective Mcl-1 inhibitors using a functional biomarker
David J. Richard et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2013)
Design, synthesis, anti-schistosomal activity and molecular docking of novel 8-hydroxyquinoline-5-sufonyl 1,4-diazepine derivatives
Ahmad F. Eweas et al.
BIOORGANIC CHEMISTRY (2013)
A Glutathione Derivative with Chelating and in vitro Neuroprotective Activities: Synthesis, Physicochemical Properties, and Biological Evaluation
Ivana Cacciatore et al.
CHEMMEDCHEM (2013)
Rationally Designed Multitarget Anti-HIV Agents
P. Zhan et al.
CURRENT MEDICINAL CHEMISTRY (2013)
Heterocycle-thioacetic Acid Motif: A Privileged Molecular Scaffold with Potent, Broad-Ranging Pharmacological Activities
Yu'ning Song et al.
CURRENT PHARMACEUTICAL DESIGN (2013)
Development of New Cathepsin B Inhibitors: Combining Bioisosteric Replacements and Structure-Based Design To Explore the Structure-Activity Relationships of Nitroxoline Derivatives
Izidor Sosic et al.
JOURNAL OF MEDICINAL CHEMISTRY (2013)
Structural Basis for Inhibition of the Fat Mass and Obesity Associated Protein (FTO)
WeiShen Aik et al.
JOURNAL OF MEDICINAL CHEMISTRY (2013)
Fragment-Based Discovery of 8-Hydroxyquinoline Inhibitors of the HIV-1 Integrase-Lens Epithelium-Derived Growth Factor/p75 (IN-LEDGF/p75) Interaction
Erik Serrao et al.
JOURNAL OF MEDICINAL CHEMISTRY (2013)
Synthesis of Perspicamide A and Related Diverse Analogues: Their Bioevaluation as Potent Antileishmanial Agents
Anand Kumar Pandey et al.
JOURNAL OF ORGANIC CHEMISTRY (2013)
New 2,3-diaminopropionic acid inhibitors of AGE and ALE formation
Nicolas Audic et al.
ORGANIC & BIOMOLECULAR CHEMISTRY (2013)
5-Carboxy-8-hydroxyquinoline is a broad spectrum 2-oxoglutarate oxygenase inhibitor which causes iron translocation
Richard J. Hopkinson et al.
CHEMICAL SCIENCE (2013)
Synthesis of 8-Hydroxyquinoline Derivatives as Novel Antitumor Agents
Sau Hing Chan et al.
ACS MEDICINAL CHEMISTRY LETTERS (2013)
A Potent (R)-alpha-bis-lipoyl Derivative Containing 8-Hydroxyquinoline Scaffold: Synthesis and Biological Evaluation of Its Neuroprotective Capabilities in SH-SY5Y Human Neuroblastoma Cells
Ivana Cacciatore et al.
PHARMACEUTICALS (2013)
Therapeutic Redistribution of Metal Ions To Treat Alzheimer's Disease
Peter J. Crouch et al.
ACCOUNTS OF CHEMICAL RESEARCH (2012)
Antiproliferative and iron chelating efficiency of the new bis-8-hydroxyquinoline benzylamine chelator S1 in hepatocyte cultures
Gerard Lescoat et al.
CHEMICO-BIOLOGICAL INTERACTIONS (2012)
Potent inhibition of dinuclear zinc(II) peptidase, an aminopeptidase from Aeromonas proteolytica, by 8-quinolinol derivatives: inhibitor design based on Zn2+ fluorophores, kinetic, and X-ray crystallographic study
Kengo Hanaya et al.
JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY (2012)
Implications of Promiscuous Pim-1 Kinase Fragment Inhibitor Hydrophobic Interactions for Fragment-Based Drug Design
Andrew C. Good et al.
JOURNAL OF MEDICINAL CHEMISTRY (2012)
Benzimidazole Heterocycle as a Privileged Scaffold in Antiviral Agents
Peng Zhan et al.
MINI-REVIEWS IN ORGANIC CHEMISTRY (2012)
Epigenetic protein families: a new frontier for drug discovery
Cheryl H. Arrowsmith et al.
NATURE REVIEWS DRUG DISCOVERY (2012)
Substituted oxines inhibit endothelial cell proliferation and angiogenesis
Shridhar Bhat et al.
ORGANIC & BIOMOLECULAR CHEMISTRY (2012)
Dopamine D2/D3 Agonists with Potent Iron Chelation, Antioxidant and Neuroprotective Properties: Potential Implication in Symptomatic and Neuroprotective Treatment of Parkinson's Disease
Sanjib Gogoi et al.
CHEMMEDCHEM (2011)
Functional Roles of Azoles Motif in Anti-HIV Agents
Peng Zhan et al.
CURRENT MEDICINAL CHEMISTRY (2011)
Identifying Chelators for Metalloprotein Inhibitors Using a Fragment-Based Approach
Jennifer A. Jacobsen et al.
JOURNAL OF MEDICINAL CHEMISTRY (2011)
8-Hydroxyquinoline-Substituted Boron-Dipyrromethene Compounds: Synthesis, Structure, and OFF-ON-OFF Type of pH-Sensing Properties
Yuting Chen et al.
JOURNAL OF ORGANIC CHEMISTRY (2011)
JLK1486, a Bis 8-Hydroxyquinoline-Substituted Benzylamine, Displays Cytostatic Effects in Experimental Gliomas through MyT1 and STAT1 Activation and, to a Lesser Extent, PPARγ Activation
Celine Bruyere et al.
TRANSLATIONAL ONCOLOGY (2011)
Identification and structure-activity relationship of 8-hydroxy-quinoline-7-carboxylic acid derivatives as inhibitors of Pim-1 kinase
Faten Sliman et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2010)
Structure-activity relationships and mechanism of action of antitumor bis 8-hydroxyquinoline substituted benzylamines
Sebastien Madonna et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2010)
Synthesis and structure-activity relationship study of 8-hydroxyquinoline-derived Mannich bases as anticancer agents
Arthur Y. Shaw et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2010)
Discovery of 4-(4-(2-((5-Hydroxy-1,2,3,4-tetrahydronaphthalen-2-yl)(propyl)amino)ethyl)piperazin-1-yl)quinolin-8-ol and Its Analogues as Highly Potent Dopamine D2/D3 Agonists and as Iron Chelator: In Vivo Activity Indicates Potential Application in Symptomatic and Neuroprotective Therapy for Parkinson's Disease
Balaram Ghosh et al.
JOURNAL OF MEDICINAL CHEMISTRY (2010)
Microwave Assisted Synthesis of a Small Library of Substituted N,N′-Bis((8-hydroxy-7-quinolinyl)methyl)-1,10-diaza-18-crown-6 Ethers
Giovanna Farruggia et al.
JOURNAL OF ORGANIC CHEMISTRY (2010)
Crystal structures of human FIH-1 in complex with quinol family inhibitors
Hyunjin Moon et al.
MOLECULES AND CELLS (2010)
Quantitative High-Throughput Screening Identifies 8-Hydroxyquinolines as Cell-Active Histone Demethylase Inhibitors
Oliver N. F. King et al.
PLOS ONE (2010)
Designed Multiple Ligands: An Emerging Anti-HIV Drug Discovery Paradigm
Peng Zhan et al.
CURRENT PHARMACEUTICAL DESIGN (2009)
Discovery of a new family of bis-8-hydroxyquinoline substituted benzylamines with pro-apoptotic activity in cancer cells: Synthesis, structure-activity relationship, and action mechanism studies
Vincent Moret et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2009)
Synthesis of Red-Shifted 8-Hydroxyquinoline Derivatives Using Click Chemistry and Their Incorporation into Phosphorylation Chemosensors
Juan A. Gonzalez-Vera et al.
JOURNAL OF ORGANIC CHEMISTRY (2009)
Multifunctional Neuroprotective Derivatives of Rasagiline as Anti-Alzheimer's Disease Drugs
Orly Weinreb et al.
NEUROTHERAPEUTICS (2009)
Recent advances in antiviral activity of benzo/heterothiadiazine dioxide derivatives
Peng Zhan et al.
CURRENT MEDICINAL CHEMISTRY (2008)
Expanding chemical biology of 2-oxoglutarate oxygenases
Christoph Loenarz et al.
NATURE CHEMICAL BIOLOGY (2008)
Privileged structures: A useful concept for the rational design of new lead drug candidates
Carolina D. Duarte et al.
MINI-REVIEWS IN MEDICINAL CHEMISTRY (2007)
Synthesis of 4-alkoxy-8-hydroxyquinolines
Juha P. Heiskanen et al.
JOURNAL OF ORGANIC CHEMISTRY (2007)
Therapeutic targets and potential of the novel brain- permeable multifunctional iron chelator-monoamine oxidase inhibitor drug, M-30, for the treatment of Alzheimer's disease
Yael Avramovich-Tirosh et al.
JOURNAL OF NEUROCHEMISTRY (2007)
8-hydroxyquinoline derivatives induce the proliferation of rat mesenchymal stem cells (rMSCs)
He-Ping Zeng et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2006)
Antifungal properties of new series of quinoline derivatives
R Musiol et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2006)
Actions of a histone deacetylase inhibitor NSC3852 (5-nitroso-8-quinolinol) link reactive oxygen species to cell differentiation and apoptosis in MCF-7 human mammary tumor cells
A Martirosyan et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2006)
A straightforward methodology for the introduction of aryl and vinyl substituents in the 5 or 7 position of 8-hydroxyquinoline
F Babudri et al.
SYNTHESIS-STUTTGART (2006)
Perspicamides A and B, quinolinecarboxylic acid derivatives from the Australian ascidian Botrylloides perspicuum
MJ McKay et al.
JOURNAL OF NATURAL PRODUCTS (2005)
Design, synthesis, and evaluation of novel bifunctional iron-chelators as potential agents for neuroprotection in Alzheimer's, Parkinson's, and other neurodegenerative diseases
HL Zheng et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2005)
Neuroprotection by a novel brain permeable iron chelator, VK-28, against 6-hydroxydopamine lession in rats
D Ben Shachar et al.
NEUROPHARMACOLOGY (2004)
Privileged structures: Applications in drug discovery
RW DeSimone et al.
COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING (2004)