期刊
MEDCHEMCOMM
卷 6, 期 1, 页码 61-74出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c4md00284a
关键词
-
资金
- National Natural Science Foundation of China (NSFC) [81102320, 81273354]
- Key Project of NSFC for International Cooperation [81420108027]
- Research Fund for the Doctoral Program of Higher Education of China [20110131130005, 20110131120037]
- Science and Technology Development Project of Shandong Province [2014GGE27154]
- China Postdoctoral Science Foundation [2012T50584]
Privileged structures can bind to a diverse range of targets with high affinities, thus benefiting the discovery of novel bioactive agents. 8-Hydroxyquinoline derivatives represent an important type of privileged structure, possessing a rich diversity of biological properties. Numerous encouraging investigations have demonstrated that this privileged structure should be further exploited for therapeutic applications in the future. In view of its predominance, and on the basis of our research interest in this scaffold, an updated and detailed account of the pharmacological properties of 8-hydroxyquinoline derivatives, as well as recent insights from structural biology, are described. Finally, some outlooks on current issues and future directions in this field of research are also provided.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据