Preparation, Characterization and Biocompatibility Study of the Scaffold Prototype Derived from Cross-Linked Poly [(epsilon-caprolactone)-co-lactide] for Tissue Engineering Materials

In this Study, we prepared cross-Linked poly [(epsilon-caprolactone)-co-lactide] scaffolds prototype by salt-leaching method using different particle size of NaCl. The characterization of these scaffolds were carried out the estimating internal morphology by scattering electron microscopy (SEM) and water content in PBS at 37 degrees C. We also studied the adhesion and proliferation of human bladder cancer cells (HBCC) to slab-type scaffold prototype by the microscopic observation of cell morphology and alarnar Blue (R) assay. These results suggest that the prototype in this study shows good biocompatibility, because the cells adhered well and penetrated into the internal pore with incubation periods. Consequently, these results indicated that the scaffold prototype Could be applied Lis practical scaffold for tissue engineering.