4.7 Article

Thermoresponsive fluorinated polyacrylamides with low cytotoxicity

期刊

POLYMER CHEMISTRY
卷 4, 期 7, 页码 2219-2223

出版社

ROYAL SOC CHEMISTRY
DOI: 10.1039/c2py20747h

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资金

  1. Priority Research Center Program [2009-0093818]
  2. Basic Science Research Program through the National Research Foundation of Korea [2010-0008642]
  3. Ministry of Education, Science, and Technology of Korea
  4. Korea Healthcare Technology R&D Project, Ministry for Health, Welfare and Family Affairs [A110096]
  5. Korea Health Promotion Institute [A110096] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)
  6. National Research Foundation of Korea [2010-0008642] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)

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We report the unique thermoresponsive properties of fluorinated polyacrylamides, poly[N-(2,2-difluoroethyl) acrylamide] (P2F). The solubility of fluorinated polyacrylamides in water can be easily controlled by changing the number of fluorine atoms in N- ethyl groups. Moreover, we demonstrate that fluorinated polyacrylamides are less cytotoxic than poly(N-isopropylacrylamide) (PNIPAM).

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