Synthesis, structure and antitumor studies of a novel decavanadate complex with a wavelike two-dimensional network

A decavanadate salt Na-4{(HOCH2CH2)(3)NH}(2)[V10O28]center dot 6H(2)O was synthesized via the reaction of sodium metavanadate and triethanolamine hydrochlorides in water solution, which exhibits an interesting wave-like 2D network in the crystal structure. The product also showed potent inhibitory activities against human laryngeal carcinoma epithelial cell line (Hep-2), human breast cancer cell line (MDA-MB-231) and hepatocellular liver carcinoma cell line (HepG(2)), which was better than the positive control drug 5-fluorouracil (5-FU), implying that newly synthesized compound may be a potential candidate for the development of anti-cancer drugs. (C) 2018 Elsevier Ltd. All rights reserved.