期刊
POLYHEDRON
卷 30, 期 12, 页码 2016-2025出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.poly.2011.05.004
关键词
Nickel ion; Hydantoin derivative; Structure; Spectroscopic properties; HSAB theory; Spectrochemical series
资金
- Polish Ministry of Higher Education and Science [NN204 331037]
- Wroclaw University of Technology
1-Methylhydantoin and its novel nickel(II) complex [Ni(H2O)(4)(1-mhyd)(2)] were prepared and identified, by elemental analysis, single crystal X-ray determination and MS methods. In addition, the complex was characterized by spectroscopic (IR, UV-Vis), magnetic and thermal techniques. The ligand reveals an interesting supramolecular architecture with both classical and non-conventional extended HB bonding networks. All rings and chains formed due to this HB bonding are embedded into the undulated pattern. A single crystal X-ray diffraction analysis of the complex shows that the nickel ion is coordinated by deprotonated hydantoin and water ligands in a N2O4 tetragonal arrangement. In the [Ni(H2O)(4)(1-mhyd)(2)] structure both inter and intramolecular hydrogen bonds are created with the participation of water molecules. The ESI-MS method confirmed mono-nuclearity of the complex while electronic spectroscopy proved the tetragonal and pseudooctahedral geometries around the metal ion in the solid state and solution, respectively. By application of the average environment rule, 10Dq parameters were obtained for the hypothetical, hexa-coordinate [Ni(1-mhyd)(6)] approximation or rather more realistic [Ni(1-mhyd)(3)] chelate. Based on this the mhyd ligand was ranked in the spectrochemical series close to ammonia. The general consideration of the structure of the hydantoin complexes as a function of the metal ion hardness within the framework of the HSAB theory has been provided. Both the ligand and the complex were found to be non-toxic agents against breast (MCF-7), lung carcinoma epithelial (A549) and mouse fibroblasts (Balb/3T3) cancer cell lines. (C) 2011 Elsevier Ltd. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据