A one pot multi-component CuAAC click approach to bidentate and tridentate pyridyl-1,2,3-triazole ligands: Synthesis, X-ray structures and copper(II) and silver(I) complexes

A one pot, multi-component CuAAC reaction has been developed for the generation of alkyl, benzyl or aryl substituted bi and tridentate pyridyl-1,2,3-triazole ligands from their corresponding halides, sodium azide and alkynes in excellent yields. The ligands have been fully characterized by elemental analysis, HR-ESMS, IR, H-1 and C-13 NMR and in the ferrocenyl substituted cases the structures were confirmed by X-ray crystallography. Additionally, we have examined the coordination chemistry of these ligands and found that a variety of geometrically diverse Cu(II) and Ag(I) complexes, including interesting tri and tetrasilver complexes, can be formed. (C) 2009 Elsevier Ltd. All rights reserved.