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注意：仅列出部分参考文献，下载原文获取全部文献信息。Molecular subtypes of NPM1 mutations have different clinical profiles, specific patterns of accompanying molecular mutations and varying outcomes in intermediate risk acute myeloid leukemia
Tamara Alpermann et al.
HAEMATOLOGICA (2016)
Low-Dose Actinomycin-D Induces Redistribution of Wild-Type and Mutated Nucleophosmin Followed by Cell Death in Leukemic Cells
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JOURNAL OF CELLULAR BIOCHEMISTRY (2016)
Molecular subtypes of NPM1 mutations have different clinical profiles, specific patterns of accompanying molecular mutations and varying outcomes in intermediate risk acute myeloid leukemia
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HAEMATOLOGICA (2016)
Altered HLA Class I Profile Associated with Type A/D Nucleophosmin Mutation Points to Possible Anti-Nucleophosmin Immune Response in Acute Myeloid Leukemia
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Differential and limited expression of mutant alleles in multiple myeloma
Naim U. Rashid et al.
BLOOD (2014)
The NPM1 Mutation Type Has No Impact on Survival in Cytogenetically Normal AML
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PLOS ONE (2014)
Structural polymorphism in the N-terminal oligomerization domain of NPM1
Diana M. Mitrea et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Role of cysteine 288 in nucleophosmin cytoplasmic mutations: sensitization to toxicity induced by arsenic trioxide and bortezomib
M. Huang et al.
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Nucleophosmin mutations in acute myeloid leukemia: A tale of protein unfolding and mislocalization
Luca Federici et al.
PROTEIN SCIENCE (2013)
A Knock-In Npm1 Mutation in Mice Results in Myeloproliferation and Implies a Perturbation in Hematopoietic Microenvironment
Shiu-Huey Chou et al.
PLOS ONE (2012)
Acute myeloid leukemia with mutated nucleophosmin (NPM1): is it a distinct entity?
Brunangelo Falini et al.
BLOOD (2011)
Targeting levels or oligomerization of nucleophosmin 1 induces differentiation and loss of survival of human AML cells with mutant NPM1
Ramesh Balusu et al.
BLOOD (2011)
Characterization of NPM1-mutated AML with a history of myelodysplastic syndromes or myeloproliferative neoplasms
S. Schnittger et al.
LEUKEMIA (2011)
A monoclonal antibody against mutated nucleophosmin 1 for the molecular diagnosis of acute myeloid leukemias
Alicja M. Gruszka et al.
BLOOD (2010)
The frequency of NPM1 mutations in childhood acute myeloid leukemia
Maria Braoudaki et al.
JOURNAL OF HEMATOLOGY & ONCOLOGY (2010)
Non-A type nucleophosmin 1 gene mutation predicts poor clinical outcome in de novo adult acute myeloid leukemia: differential clinical importance of NPM1 mutation according to subtype
Youngil Koh et al.
INTERNATIONAL JOURNAL OF HEMATOLOGY (2009)
A dose-dependent tug of war involving the NPM1 leukaemic mutant, nucleophosmin, and ARF
N. Bolli et al.
LEUKEMIA (2009)
Structural Consequences of Nucleophosmin Mutations in Acute Myeloid Leukemia
Charles G. Grummitt et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Born to be exported: COOH-terminal nuclear export signals of different strength ensure cytoplasmic accumulation of nucleophosmin leukemic mutants
Niccolo Bolli et al.
CANCER RESEARCH (2007)
Translocations and mutations involving the nucleophosmin (NPM1) gene in lymphomas and leukemias
Brunangelo Falini et al.
HAEMATOLOGICA (2007)
Acute myeloid leukemia carrying cytoplasmic/mutated nucleophosmin (NPMc+ AML):: biologic and clinical features
Brunangelo Falini et al.
BLOOD (2007)
Aberrant cytoplasmic expression of C-terminal-truncated NPM leukaemic mutant is dictated by tryptophans loss and a new NES motif
B. Falini et al.
LEUKEMIA (2007)
Immunohistochemistry predicts nucleophosmin (NPM) mutations in acute myeloid leukemia
Brunangelo Falini et al.
BLOOD (2006)
Essential role of the B23/NPM core domain in regulating ARF binding and B23 stability
Takeharu Enomoto et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Prevalence and prognostic impact of NPM1 mutations in 1485 adult patients with acute myeloid leukemia (AML)
Christian Thiede et al.
BLOOD (2006)
Mutations in nucleophosmin (NPM1) in acute myeloid leukemia (AML):: association with other gene abnormalities and previously established gene expression signatures and their favorable prognostic significance
RGW Verhaak et al.
BLOOD (2005)
Nucleophosmin gene mutations are predictors of favorable prognosis in acute myelogenous leukemia with a normal karyotype
S Schnittger et al.
BLOOD (2005)
Mutant nucleophosmin (NPM1) predicts favorable prognosis in younger adults with acute myeloid leukemia and normal cytogenetics:: interaction with other gene mutations
K Döhner et al.
BLOOD (2005)
Role of nucleophosmin in embryonic development and tumorigenesis
S Grisendi et al.
NATURE (2005)
Cytoplasmic nucleophosmin in acute myelogenous leukemia with a normal karyotype.
B Falini et al.
NEW ENGLAND JOURNAL OF MEDICINE (2005)
Physical and functional interactions of the Arf tumor suppressor protein with nucleophosmin/B23
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MOLECULAR AND CELLULAR BIOLOGY (2004)
Tumor suppressor ARF degrades B23, a nucleolar protein involved in ribosome biogenesis and cell proliferation
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MOLECULAR CELL (2003)
The role of nucleophosmin in centrosome duplication
M Okuda
ONCOGENE (2002)
Mapping the functional domains of nucleolar protein B23
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JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
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