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注意：仅列出部分参考文献，下载原文获取全部文献信息。Targeting CAG repeat RNAs reduces Huntington's disease phenotype independently of huntingtin levels
Laura Rue et al.
JOURNAL OF CLINICAL INVESTIGATION (2016)
A Longitudinal Study of Magnetic Resonance Spectroscopy Huntington's Disease Biomarkers
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MOVEMENT DISORDERS (2015)
Sex differences in Parkinson's disease and other movement disorders
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In Vivo Evaluation of Candidate Allele-specific Mutant Huntingtin Gene Silencing Antisense Oligonucleotides
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MOLECULAR THERAPY (2014)
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MOVEMENT DISORDERS (2014)
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MOVEMENT DISORDERS (2014)
Role of Context in RNA Structure: Flanking Sequences Reconfigure CAG Motif Folding in Huntingtin Exon 1 Transcripts
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BIOCHEMISTRY (2013)
The influence of gender on phenotype and disease progression in patients with Huntington's disease
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PARKINSONISM & RELATED DISORDERS (2013)
Mechanisms of RNA-induced toxicity in CAG repeat disorders
R. Nalavade et al.
CELL DEATH & DISEASE (2013)
An open system for automatic home-cage behavioral analysis and its application to male and female mouse models of Huntington's disease
Kourosh Zarringhalam et al.
BEHAVIOURAL BRAIN RESEARCH (2012)
Single-Stranded RNAs Use RNAi to Potently and Allele-Selectively Inhibit Mutant Huntingtin Expression
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CELL (2012)
TR-FRET-Based Duplex Immunoassay Reveals an Inverse Correlation of Soluble and Aggregated Mutant huntingtin in Huntington's Disease
Barbara Baldo et al.
CHEMISTRY & BIOLOGY (2012)
Cortical metabolites as biomarkers in the R6/2 model of Huntington's disease
Lori Zacharoff et al.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2012)
R6/2 Huntington's Disease Mice Develop Early and Progressive Abnormal Brain Metabolism and Seizures
Efrain Cepeda-Prado et al.
JOURNAL OF NEUROSCIENCE (2012)
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Liliana B. Menalled et al.
PLOS ONE (2012)
Characterization of Neurophysiological and Behavioral Changes, MRI Brain Volumetry and 1H MRS in zQ175 Knock-In Mouse Model of Huntington's Disease
Taneli Heikkinen et al.
PLOS ONE (2012)
Potent and Selective Antisense Oligonucleotides Targeting Single-Nucleotide Polymorphisms in the Huntington Disease Gene/Allele-Specific Silencing of Mutant Huntingtin
Jeffrey B. Carroll et al.
MOLECULAR THERAPY (2011)
Sexually Dimorphic Serotonergic Dysfunction in a Mouse Model of Huntington's Disease and Depression
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PLOS ONE (2011)
Targeting Several CAG Expansion Diseases by a Single Antisense Oligonucleotide
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PLOS ONE (2011)
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BIOCHEMISTRY (2010)
Increased transcript diversity: novel splicing variants of Machado-Joseph Disease gene (ATXN3)
Conceicao Bettencourt et al.
NEUROGENETICS (2010)
Molecular Mechanisms and Potential Therapeutical Targets in Huntington's Disease
Chiara Zuccato et al.
PHYSIOLOGICAL REVIEWS (2010)
A majority of Huntington's disease patients may be treatable by individualized allele-specific RNA interference
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EXPERIMENTAL NEUROLOGY (2009)
Alterations in Cortical Excitation and Inhibition in Genetic Mouse Models of Huntington's Disease
Damian M. Cummings et al.
JOURNAL OF NEUROSCIENCE (2009)
Allele-specific silencing of mutant huntingtin and ataxin-3 genes by targeting expanded CAG repeats in mRNAs
Jiaxin Hu et al.
NATURE BIOTECHNOLOGY (2009)
Systematic behavioral evaluation of Huntington's disease transgenic and knock-in mouse models
Liliana Menalled et al.
NEUROBIOLOGY OF DISEASE (2009)
Sex differences in behavior and striatal ascorbate release in the 140 CAG knock-in mouse model of Huntington's disease
Jenelle L. Dorner et al.
BEHAVIOURAL BRAIN RESEARCH (2007)
Neurochemical changes in Huntington R6/2 mouse striatum detected by in vivo 1H NMR spectroscopy
Ivan Tkac et al.
JOURNAL OF NEUROCHEMISTRY (2007)
Plasma testosterone in male patients with Huntington's disease: Relations to severity of illness and dementia
M Markianos et al.
ANNALS OF NEUROLOGY (2005)
Evidence for more widespread cerebral pathology in early HD - An MRI-based morphometric analysis
HD Rosas et al.
NEUROLOGY (2003)
Analysis of relative gene expression data using real-time quantitative PCR and the 2-ΔΔCT method
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METHODS (2001)
Nonlinear decrease over time in N-acetyl aspartate levels in the absence of neuronal loss and increases in glutamine and glucose in transgenic Huntington's disease mice
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JOURNAL OF NEUROCHEMISTRY (2000)
N-acetylaspartate and DARPP-32 levels decrease in the corpus striatum of Huntington's disease mice
A van Dellen et al.
NEUROREPORT (2000)
Severe deficiencies in dopamine signaling in presymptomatic Huntington's disease mice
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
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