期刊
CHEMICAL SCIENCE
卷 6, 期 2, 页码 1043-1048出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c4sc03047h
关键词
-
资金
- MEXT Japan [25288045]
- JST, Exploratory Research [25670055]
- Grants-in-Aid for Scientific Research [25288045] Funding Source: KAKEN
We report on the self-disproportionation of enantiomers (SDE) of non-racemic thalidomide (1) and 3'-fluorothalidomide (2) under the conditions of gravity-driven achiral silica-gel chromatography. The presence of a fluorine atom on the chiral center dramatically alters the structure and polarity of 1 and 2, resulting in the opposite SDE profile on silica-gel.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据