相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。T-Cell-Receptor-Dependent Signal Intensity Dominantly Controls CD4+ T Cell Polarization In Vivo
Nicholas van Panhuys et al.
IMMUNITY (2014)
CCR7 provides localized access to IL-2 and defines homeostatically distinct regulatory T cell subsets
Kate S. Smigiel et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2014)
The AGC kinase SGK1 regulates TH1 and TH2 differentiation downstream of the mTORC2 complex
Emily B. Heikamp et al.
NATURE IMMUNOLOGY (2014)
Integrating canonical and metabolic signalling programmes in the regulation of T cell responses
Kristen N. Pollizzi et al.
NATURE REVIEWS IMMUNOLOGY (2014)
T Cell Activation Threshold Regulated by E3 Ubiquitin Ligase Cbl-b Determines Fate of Inducible Regulatory T Cells
Guilin Qiao et al.
JOURNAL OF IMMUNOLOGY (2013)
mTOR is a key modulator of ageing and age-related disease
Simon C. Johnson et al.
NATURE (2013)
mTORC1 couples immune signals and metabolic programming to establish Treg-cell function
Hu Zeng et al.
NATURE (2013)
CD8 memory T cells have a bioenergetic advantage that underlies their rapid recall ability
Gerritje J. W. van der Windt et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
The Duration of T Cell Stimulation Is a Critical Determinant of Cell Fate and Plasticity
Natasa Miskov-Zivanov et al.
SCIENCE SIGNALING (2013)
Regulation of Immune Responses by mTOR
Jonathan D. Powell et al.
ANNUAL REVIEW OF IMMUNOLOGY, VOL 30 (2012)
mTOR Signaling in Growth Control and Disease
Mathieu Laplante et al.
CELL (2012)
Mitochondrial Respiratory Capacity Is a Critical Regulator of CD8+ T Cell Memory Development
Gerritje J. W. van der Windt et al.
IMMUNITY (2012)
T Cell Affinity Regulates Asymmetric Division, Effector Cell Differentiation, and Tissue Pathology
Carolyn G. King et al.
IMMUNITY (2012)
Mammalian Target of Rapamycin Integrates Diverse Inputs To Guide the Outcome of Antigen Recognition in T Cells
Adam T. Waickman et al.
JOURNAL OF IMMUNOLOGY (2012)
A unifying model for mTORC1-mediated regulation of mRNA translation
Carson C. Thoreen et al.
NATURE (2012)
TSC1/2 Signaling Complex Is Essential for Peripheral Naive CD8+ T Cell Survival and Homeostasis in Mice
Lianjun Zhang et al.
PLOS ONE (2012)
The kinase mTOR regulates the differentiation of helper T cells through the selective activation of signaling by mTORC1 and mTORC2
Greg M. Delgoffe et al.
NATURE IMMUNOLOGY (2011)
Characterization of the Metabolic Phenotype of Rapamycin-Treated CD8+ T Cells with Augmented Ability to Generate Long-Lasting Memory Cells
Shan He et al.
PLOS ONE (2011)
An Oscillatory Switch in mTOR Kinase Activity Sets Regulatory T Cell Responsiveness
Claudio Procaccini et al.
IMMUNITY (2010)
The mTOR Kinase Determines Effector versus Memory CD8+ T Cell Fate by Regulating the Expression of Transcription Factors T-bet and Eomesodermin
Rajesh R. Rao et al.
IMMUNITY (2010)
TCR ligand density and affinity determine peripheral induction of Foxp3 in vivo
Rachel A. Gottschalk et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2010)
Activation of a Metabolic Gene Regulatory Network Downstream of mTOR Complex 1
Katrin Duevel et al.
MOLECULAR CELL (2010)
The mTOR Kinase Differentially Regulates Effector and Regulatory T Cell Lineage Commitment
Greg M. Delgoffe et al.
IMMUNITY (2009)
mTOR signaling at a glance
Mathieu Laplante et al.
JOURNAL OF CELL SCIENCE (2009)
Foxp3-Deficient Regulatory T Cells Do Not Revert into Conventional Effector CD4+ T Cells but Constitute a Unique Cell Subset
Michal Kuczma et al.
JOURNAL OF IMMUNOLOGY (2009)
Bioenergetic analysis of isolated cerebrocortical nerve terminals on a microgram scale: spare respiratory capacity and stochastic mitochondrial failure
Sung W. Choi et al.
JOURNAL OF NEUROCHEMISTRY (2009)
Enhanced interaction between Hsp90 and raptor regulates mTOR signaling upon T cell activation
Greg M. Delgoffe et al.
MOLECULAR IMMUNOLOGY (2009)
Enhancing CD8 T-cell memory by modulating fatty acid metabolism
Erika L. Pearce et al.
NATURE (2009)
mTOR regulates memory CD8 T-cell differentiation
Koichi Araki et al.
NATURE (2009)
Active-Site Inhibitors of mTOR Target Rapamycin-Resistant Outputs of mTORC1 and mTORC2
Morris E. Feldman et al.
PLOS BIOLOGY (2009)
The AKT-mTOR axis regulates de novo differentiation of CD4+Foxp3+ cells
Sokol Haxhinasto et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2008)
De novo induction of antigen-specific CD4+CD25+Foxp3+ regulatory T cells in vivo following systemic antigen administration accompanied by blockade of mTOR
Johnthomas Kang et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2008)
Differential impact of mammalian target of rapamycin inhibition on CD4(+)CD25(+)Foxp3(+) regulatory T cells compared with conventional CD4(+) T cells
Robert Zeiser et al.
BLOOD (2008)
Generation of a conditional disruption of the Tsc2 gene
Omar Hernandez et al.
GENESIS (2007)
Cyclin D1 and c-myc internal ribosome entry site (IRES)-dependent translation is regulated by AKT activity and enhanced by rapamycin through a p38 MAPK- and ERK-dependent pathway
YJ Shi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
TGF-β induces Foxp3+T-regulatory cells from CD4+CD25-precursors
S Fu et al.
AMERICAN JOURNAL OF TRANSPLANTATION (2004)
Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-β induction of transcription factor Foxp3
WJ Chen et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2003)
Rheb is a direct target of the tuberous sclerosis tumour suppressor proteins
Y Zhang et al.
NATURE CELL BIOLOGY (2003)
Regulation of hypoxia-inducible factor 1α expression and function by the mammalian target of rapamycin
CC Hudson et al.
MOLECULAR AND CELLULAR BIOLOGY (2002)
Mammalian cell size is controlled by mTOR and its downstream targets S6K1 and 4EBP1/eIF4E
DC Fingar et al.
GENES & DEVELOPMENT (2002)
Hematopoietic stem cell quiescence maintained by p21cip1/waf1
T Cheng et al.
SCIENCE (2000)
分享论文
