相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。FGF21-based pharmacotherapy - potential utility for metabolic disorders
Ruth E. Gimeno et al.
TRENDS IN ENDOCRINOLOGY AND METABOLISM (2014)
Differential Enzyme-Linked Immunosorbent Assay and Ligand-Binding Mass Spectrometry for Analysis of Biotransformation of Protein Therapeutics: Application to Various FGF21 Modalities
Todd Hager et al.
ANALYTICAL CHEMISTRY (2013)
NCoR Repression of LXRs Restricts Macrophage Biosynthesis of Insulin-Sensitizing Omega 3 Fatty Acids
Pingping Li et al.
CELL (2013)
Adiponectin Mediates the Metabolic Effects of FGF21 on Glucose Homeostasis and Insulin Sensitivity in Mice
Zhuofeng Lin et al.
CELL METABOLISM (2013)
FGF21 Mimetic Shows Therapeutic Promise
Marc L. Reitman
CELL METABOLISM (2013)
An FGF21-Adiponectin-Ceramide Axis Controls Energy Expenditure and Insulin Action in Mice
William L. Holland et al.
CELL METABOLISM (2013)
The Effects of LY2405319, an FGF21 Analog, in Obese Human Subjects with Type 2 Diabetes
Gregory Gaich et al.
CELL METABOLISM (2013)
Fibroblast Growth Factor 21 Improves Insulin Resistance and Ameliorates Renal Injury in db/db Mice
H. W. Kim et al.
ENDOCRINOLOGY (2013)
Neuronal Sirt1 Deficiency Increases Insulin Sensitivity in Both Brain and Peripheral Tissues
Min Lu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Exploring mechanisms of FGF signalling through the lens of structural biology
Regina Goetz et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2013)
Rational Design of a Fibroblast Growth Factor 21-Based Clinical Candidate, LY2405319
Alexei Kharitonenkov et al.
PLOS ONE (2013)
LY2405319, an Engineered FGF21 Variant, Improves the Metabolic Status of Diabetic Monkeys
Andrew C. Adams et al.
PLOS ONE (2013)
Development of a Novel Long-Acting Antidiabetic FGF21 Mimetic by Targeted Conjugation to a Scaffold Antibody
Jie Huang et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2013)
βKlotho Is Required for Fibroblast Growth Factor 21 Effects on Growth and Metabolism
Xunshan Ding et al.
CELL METABOLISM (2012)
FGF21 Analogs of Sustained Action Enabled by Orthogonal Biosynthesis Demonstrate Enhanced Antidiabetic Pharmacology in Rodents
James Mu et al.
DIABETES (2012)
Long-Acting FGF21 Has Enhanced Efficacy in Diet-Induced Obese Mice and in Obese Rhesus Monkeys
Murielle M. Veniant et al.
ENDOCRINOLOGY (2012)
FGF21 regulates PGC-1α and browning of white adipose tissues in adaptive thermogenesis
Ffolliott M. Fisher et al.
GENES & DEVELOPMENT (2012)
Dynamics and Distribution of Klothoβ (KLB) and Fibroblast Growth Factor Receptor-1 (FGFR1) in Living Cells Reveal the Fibroblast Growth Factor-21 (FGF21)-induced Receptor Complex
Aaron Y. K. Ming et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
A guide to analysis of mouse energy metabolism
Matthias H. Tschoep et al.
NATURE METHODS (2012)
Fundamentals of FGF19 & FGF21 Action In Vitro and In Vivo
Andrew C. Adams et al.
PLOS ONE (2012)
FGF21 Promotes Metabolic Homeostasis via White Adipose and Leptin in Mice
Murielle M. Veniant et al.
PLOS ONE (2012)
Treating Diabetes and Obesity with an FGF21-Mimetic Antibody Activating the βKlotho/FGFR1c Receptor Complex
Ian N. Foltz et al.
SCIENCE TRANSLATIONAL MEDICINE (2012)
FGF19 Regulates Cell Proliferation, Glucose and Bile Acid Metabolism via FGFR4-Dependent and Independent Pathways
Ai-Luen Wu et al.
PLOS ONE (2011)
Circulating FGF21 Levels Are Progressively Increased from the Early to End Stages of Chronic Kidney Diseases and Are Associated with Renal Function in Chinese
Zhuofeng Lin et al.
PLOS ONE (2011)
FGF21 reloaded: challenges of a rapidly growing field
Alexei Kharitonenkov et al.
TRENDS IN ENDOCRINOLOGY AND METABOLISM (2011)
Fibroblast growth factor 21: from pharmacology to physiology
Steven A. Kliewer et al.
AMERICAN JOURNAL OF CLINICAL NUTRITION (2010)
Fibroblast Growth Factor 21 Action in the Brain Increases Energy Expenditure and Insulin Sensitivity in Obese Rats
David A. Sarruf et al.
DIABETES (2010)
Research Resource: Comprehensive Expression Atlas of the Fibroblast Growth Factor System in Adult Mouse
Klementina Fon Tacer et al.
MOLECULAR ENDOCRINOLOGY (2010)
Fibroblast Growth Factor 21 Reverses Hepatic Steatosis, Increases Energy Expenditure, and Improves Insulin Sensitivity in Diet-Induced Obese Mice
Jing Xu et al.
DIABETES (2009)
Serum Levels of the Adipokine FGF21 Depend on Renal Function
Sebastian Stein et al.
DIABETES CARE (2009)
FGF21 N- and C-termini play different roles in receptor interaction and activation
Junming Yie et al.
FEBS LETTERS (2009)
Different Roles of N- and C-Termini in the Functional Activity of FGF21
Radmila Micanovic et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2009)
Estimating the Continuous-Time Dynamics of Energy and Fat Metabolism in Mice
Juen Guo et al.
PLOS COMPUTATIONAL BIOLOGY (2009)
Fibroblast Growth Factor 21 Corrects Obesity in Mice
Tamer Coskun et al.
ENDOCRINOLOGY (2008)
What is the required energy deficit per unit weight loss?
K. D. Hall
INTERNATIONAL JOURNAL OF OBESITY (2008)
Molecular insights into the klotho-dependent, endocrine mode of action of fibroblast growth factor 19 subfamily members
Regina Goetz et al.
MOLECULAR AND CELLULAR BIOLOGY (2007)
FGF-21 as a novel metabolic regulator
A Kharitonenkov et al.
JOURNAL OF CLINICAL INVESTIGATION (2005)