相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Crystal Structure of Cas9 in Complex with Guide RNA and Target DNA
Hiroshi Nishimasu et al.
CELL (2014)
Analysis of off-target effects of CRISPR/Cas-derived RNA-guided endonucleases and nickases
Seung Woo Cho et al.
GENOME RESEARCH (2014)
DNA interrogation by the CRISPR RNA-guided endonuclease Cas9
Samuel H. Sternberg et al.
NATURE (2014)
Genome-wide binding of the CRISPR endonuclease Cas9 in mammalian cells
Xuebing Wu et al.
NATURE BIOTECHNOLOGY (2014)
Improving CRISPR-Cas nuclease specificity using truncated guide RNAs
Yanfang Fu et al.
NATURE BIOTECHNOLOGY (2014)
Genome-wide analysis reveals characteristics of off-target sites bound by the Cas9 endonuclease
Cem Kuscu et al.
NATURE BIOTECHNOLOGY (2014)
Genome editing with Cas9 in adult mice corrects a disease mutation and phenotype
Hao Yin et al.
NATURE BIOTECHNOLOGY (2014)
Efficient genome modification by CRISPR-Cas9 nickase with minimal off-target effects
Bin Shen et al.
NATURE METHODS (2014)
Hox in motion: tracking HoxA cluster conformation during differentiation
Mathieu Rousseau et al.
NUCLEIC ACIDS RESEARCH (2014)
One-Step Generation of Mice Carrying Mutations in Multiple Genes by CRISPR/Cas-Mediated Genome Engineering
Haoyi Wang et al.
CELL (2013)
Double Nicking by RNA-Guided CRISPR Cas9 for Enhanced Genome Editing Specificity
F. Ann Ran et al.
CELL (2013)
CRISPR-Mediated Modular RNA-Guided Regulation of Transcription in Eukaryotes
Luke A. Gilbert et al.
CELL (2013)
Functional Repair of CFTR by CRISPR/Cas9 in Intestinal Stem Cell Organoids of Cystic Fibrosis Patients
Gerald Schwank et al.
CELL STEM CELL (2013)
Correction of a Genetic Disease in Mouse via Use of CRISPR-Cas9
Yuxuan Wu et al.
CELL STEM CELL (2013)
Repurposing CRISPR/Cas9 for in situ functional assays
Abba Malina et al.
GENES & DEVELOPMENT (2013)
Transgene-Free Genome Editing in Caenorhabditis elegans Using CRISPR-Cas
Hui Chiu et al.
GENETICS (2013)
CAS9 transcriptional activators for target specificity screening and paired nickases for cooperative genome engineering
Prashant Mali et al.
NATURE BIOTECHNOLOGY (2013)
DNA targeting specificity of RNA-guided Cas9 nucleases
Patrick D. Hsu et al.
NATURE BIOTECHNOLOGY (2013)
High-throughput profiling of off-target DNA cleavage reveals RNA-programmed Cas9 nuclease specificity
Vikram Pattanayak et al.
NATURE BIOTECHNOLOGY (2013)
High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells
Yanfang Fu et al.
NATURE BIOTECHNOLOGY (2013)
RNA-guided editing of bacterial genomes using CRISPR-Cas systems
Wenyan Jiang et al.
NATURE BIOTECHNOLOGY (2013)
Cas9 as a versatile tool for engineering biology
Prashant Mali et al.
NATURE METHODS (2013)
CRISPR/Cas9 systems targeting β-globin and CCR5 genes have substantial off-target activity
Thomas J. Cradick et al.
NUCLEIC ACIDS RESEARCH (2013)
RNA-Guided Human Genome Engineering via Cas9
Prashant Mali et al.
SCIENCE (2013)
Multiplex Genome Engineering Using CRISPR/Cas Systems
Le Cong et al.
SCIENCE (2013)
Fast gapped-read alignment with Bowtie 2
Ben Langmead et al.
NATURE METHODS (2012)
A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity
Martin Jinek et al.
SCIENCE (2012)
MEME-ChIP: motif analysis of large DNA datasets
Philip Machanick et al.
BIOINFORMATICS (2011)
Efficient yeast ChIP-Seq using multiplex short-read DNA sequencing
Philippe Lefrancois et al.
BMC GENOMICS (2009)
Small-molecule MDM2 antagonists reveal aberrant p53 signaling in cancer: Implications for therapy
C Tovar et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Oncogenic ras activates the ARF-p53 pathway to suppress epithelial cell transformation
AW Lin et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
分享论文
