期刊
PLOS ONE
卷 9, 期 12, 页码 -出版社
PUBLIC LIBRARY SCIENCE
DOI: 10.1371/journal.pone.0115583
关键词
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资金
- Science Foundation of Ireland [SSPC2 12/RC/2275, 13-TIDA-B2625, 07/IN.1/B948, 12/TIDA/B2411, 12/TIDA/B2405, 09/RFP/BMT 2350]
- Department of Agriculture, Fisheries and Food (FIRM/RSF/CoFoRD) [DAFF11/F/009 MabS, FIRM 08/RDC/629]
- Environmental Protection Agency (EPA) [2008-PhD/S-2]
- Irish Research Council for Science, Engineering and Technology [PD/2011/2414, RS/2010/2413]
- European Commission (FP7-PEOPLE-ITN) [607786]
- European Commission (OCEAN) [287589]
- European Commission (FP7-KBBE-6) [CP-TP 311975]
- European Commission (Marie Curie) [256596]
- Marine Institute [C2CRA 2007/082]
- Teagasc
- Health Research Board [HRA/2009/146]
A better understanding of the origin and natural reservoirs of resistance determinants is fundamental to efficiently tackle antibiotic resistance. This paper reports the identification of a novel 5.8 kb erythromycin resistance plasmid, from Bacillus sp. HS24 isolated from the marine sponge Haliclona simulans. pBHS24B has a mosaic structure and carries the erythromycin resistance gene erm(T). This is the first report of an erythromycin resistance plasmid from a sponge associated bacteria and of the Erm(T) determinant in the genus Bacillus.
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