4.6 Article

Molecular Analysis of the Cold Tolerant Antarctic Nematode, Panagrolaimus davidi

期刊

PLOS ONE
卷 9, 期 8, 页码 -

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PUBLIC LIBRARY SCIENCE
DOI: 10.1371/journal.pone.0104526

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资金

  1. NERC core funding
  2. Japan Society [23510239]
  3. Transdisciplinary Research Integration Center (TRIC)
  4. Research Organisation of Information and Systems (ROIS)
  5. Departments of Zoology and Biochemistry at the University of Otago
  6. Grants-in-Aid for Scientific Research [23510239, 23247012] Funding Source: KAKEN
  7. Natural Environment Research Council [bas0100025] Funding Source: researchfish
  8. NERC [bas0100025] Funding Source: UKRI

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Isolated and established in culture from the Antarctic in 1988, the nematode Panagrolaimus davidi has proven to be an idel model for the study of adaptation to the cold. Not only is it the best-documented example of an organism surviving intracellular freezing but it is also able to undergo cryoprotective dehydration. As part of an ongoing effort to develop a molecular understanding of this remarkable organism, we have assembled both a transcriptome and a set of genomic scaffolds. We provide an overview of the transcriptome and a survey of genes involved in temperature stress. We also explore, in silico, the possibility that P. davidi will be susceptible to an environmental RNAi response, important for further functional studies.

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