相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Wnt Signaling through Inhibition of β-Catenin Degradation in an Intact Axin1 Complex
Vivian S. W. Li et al.
CELL (2012)
Wnt/β-Catenin Signaling and Disease
Hans Clevers et al.
CELL (2012)
Adenomatous Polyposis Coli (APC) Regulates Multiple Signaling Pathways by Enhancing Glycogen Synthase Kinase-3 (GSK-3) Activity
Alexander J. Valvezan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Reversible Modification of Adenomatous Polyposis Coli (APC) with K63-linked Polyubiquitin Regulates the Assembly and Activity of the β-Catenin Destruction Complex
Hoanh Tran et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Triple SILAC to Determine Stimulus Specific Interactions in the Wnt Pathway
Maximiliane Hilger et al.
JOURNAL OF PROTEOME RESEARCH (2012)
Comprehensive molecular characterization of human colon and rectal cancer
Donna M. Muzny et al.
NATURE (2012)
A Common Role for Various Human Truncated Adenomatous Polyposis Coli Isoforms in the Control of Beta-Catenin Activity and Cell Proliferation
Shree Harsha Vijaya Chandra et al.
PLOS ONE (2012)
Kinetic Responses of β-Catenin Specify the Sites of Wnt Control
Ana R. Hernandez et al.
SCIENCE (2012)
APC mutations in colorectal tumours from FAP patients are selected for CtBP-mediated oligomerization of truncated APC
Jean Schneikert et al.
HUMAN MOLECULAR GENETICS (2011)
Deconstructing the βcatenin destruction complex: mechanistic roles for the tumor suppressor APC in regulating Wnt signaling
David M. Roberts et al.
MOLECULAR BIOLOGY OF THE CELL (2011)
Dishevelled interacts with the DIX domain polymerization interface of Axin to interfere with its function in down-regulating β-catenin
Marc Fiedler et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
The Adenomatous polyposis coli tumour suppressor is essential for Axin complex assembly and function and opposes Axin's interaction with Dishevelled
Carolina Mendoza-Topaz et al.
OPEN BIOLOGY (2011)
Contribution of the 15 amino acid repeats of truncated APC to β-catenin degradation and selection of APC mutations in colorectal tumours from FAP patients
E. M. Kohler et al.
ONCOGENE (2010)
Wnt/β-Catenin Signaling: Components, Mechanisms, and Diseases
Bryan T. MacDonald et al.
DEVELOPMENTAL CELL (2009)
β-Catenin degradation mediated by the CID domain of APC provides a model for the selection of APC mutations in colorectal, desmoid and duodenal tumours
Eva Maria Kohler et al.
HUMAN MOLECULAR GENETICS (2009)
A Targeted Constitutive Mutation in the Apc Tumor Suppressor Gene Underlies Mammary But Not Intestinal Tumorigenesis
Claudia Gaspar et al.
PLOS GENETICS (2009)
Cell regulation by the Apc protein.: Apc as master regulator of epithelia
Brooke M. McCartney et al.
CURRENT OPINION IN CELL BIOLOGY (2008)
Functional definition of the mutation cluster region of adenomatous polyposis coli in colorectal tumours
Eva Maria Kohler et al.
HUMAN MOLECULAR GENETICS (2008)
Novel self-association of the APC molecule affects APC clusters and cell migration
Zhuoyu Li et al.
JOURNAL OF CELL SCIENCE (2008)
Recruitment of adenomatous polyposis coli and β-catenin to axin-puncta
M. C. Faux et al.
ONCOGENE (2008)
AMER1 regulates the distribution of the tumor suppressor APC between microtubules and the plasma membrane
Annette Grohmann et al.
JOURNAL OF CELL SCIENCE (2007)
The DIX domain of Dishevelled confers Wnt signaling by dynamic polymerization
Thomas Schwarz-Romond et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2007)
Wilms tumor suppressor WTX negatively regulates WNT/β-catenin signaling
Michael B. Major et al.
SCIENCE (2007)
Truncated APC regulates the transcriptional activity of β-catenin in a cell cycle dependent manner
Jean Schneikert et al.
HUMAN MOLECULAR GENETICS (2007)
The canonical Wnt signalling pathway and its APC partner in colon cancer development
Jean Schneikert et al.
GUT (2007)
Adenomatous polyposis coli (APC) differentially regulates β-catenin phosphorylation and ubiquitination in colon cancer cells
Jun Yang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
The third 20 amino acid repeat is the tightest binding site of APC for β-catenin
Jing Liu et al.
JOURNAL OF MOLECULAR BIOLOGY (2006)
Nucleo-cytoplasmic distribution of β-catenin is regulated by retention
E Krieghoff et al.
JOURNAL OF CELL SCIENCE (2006)
Nucleo-cytoplasmic shuttling of axin, a negative regulator of the Wnt-β-catenin pathway
N Wiechens et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Mechanism of phosphorylation-dependent binding of APC to β-catenin and its role in β-catenin degradation
NC Ha et al.
MOLECULAR CELL (2004)
Crystal structure of a β-Catenin/APC complex reveals a critical role for APC phosphorylation in APC function
Y Xing et al.
MOLECULAR CELL (2004)
Interaction with IQGAP1 links APC to Rac1, Cdc42, and actin filaments during cell polarization and migration
T Watanabe et al.
DEVELOPMENTAL CELL (2004)
Downregulation of β-catenin by p53 involves changes in the rate of β-catenin phosphorylation and Axin dynamics
E Levina et al.
ONCOGENE (2004)
The roles of APC and axin derived from experimental and theoretical analysis of the Wnt pathway
E Lee et al.
PLOS BIOLOGY (2003)
Nuclear export of the APC tumour suppressor controls β-catenin function in transcription
R Rosin-Arbesfeld et al.
EMBO JOURNAL (2003)
The adenomatous polyposis coli protein unambiguously localizes to microtubule plus ends and is involved in establishing parallel arrays of microtubule bundles in highly polarized epithelial cells
MM Mogensen et al.
JOURNAL OF CELL BIOLOGY (2002)
Identification of a link between the tumour suppressor APC and the kinesin superfamily
T Jimbo et al.
NATURE CELL BIOLOGY (2002)
Negative feedback loop of Wnt signaling through upregulation of conductin/Axin2 in colorectal and liver tumors
B Lustig et al.
MOLECULAR AND CELLULAR BIOLOGY (2002)
Wnt signals are transmitted through N-terminally dephosphorylated beta-catenin
FJT Staal et al.
EMBO REPORTS (2002)
Molecular mechanisms of β-catenin recognition by adenomatous polyposis coli revealed by the structure of an APC-β-catenin complex
KE Spink et al.
EMBO JOURNAL (2001)
Inhibition of Wnt signaling pathway by a novel axin-binding protein
T Kadoya et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Complex formation of adenomatous polyposis coli gene product and Axin facilitates glycogen synthase kinase-3β-dependent phosphorylation of β-catenin and down-regulates β-catenin
T Hinoi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Asef, a link between the tumor suppressor APC and G-protein signaling
Y Kawasaki et al.
SCIENCE (2000)
Crystal structure of the amino-terminal coiled-coil domain of the APC tumor suppressor
CL Day et al.
JOURNAL OF MOLECULAR BIOLOGY (2000)
Structural basis of the Axin-adenomatous polyposis coli interaction
KE Spink et al.
EMBO JOURNAL (2000)
APC mutations in sporadic colorectal tumors:: A mutational hotspot and interdependence of the two hits
AJ Rowan et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)