相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Molecular mechanism of action of metformin: old or new insights?
Graham Rena et al.
DIABETOLOGIA (2013)
Potential applications for biguanides in oncology
Michael Pollak
JOURNAL OF CLINICAL INVESTIGATION (2013)
Role of antioxidants in cancer therapy
Vanessa Fuchs-Tarlovsky
NUTRITION (2013)
Metformin Therapy and Risk of Cancer in Patients with Type 2 Diabetes: Systematic Review
Monica Franciosi et al.
PLOS ONE (2013)
Growth Signals, Inflammation, and Vascular Perturbations Mechanistic Links Between Obesity, Metabolic Syndrome, and Cancer
Stephen D. Hursting et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2012)
Isolated and combined action of tamoxifen and metformin in wild-type, tamoxifen-resistant, and estrogen-deprived MCF-7 cells
Lev M. Berstein et al.
BREAST CANCER RESEARCH AND TREATMENT (2011)
Metformin Amplifies Chemotherapy-Induced AMPK Activation and Antitumoral Growth
Guilherme Z. Rocha et al.
CLINICAL CANCER RESEARCH (2011)
Metformin reduces the stimulatory effect of obesity on in vivo Walker-256 tumor development and increases the area of tumor necrosis
Eveline Aparecida Isquierdo Fonseca et al.
LIFE SCIENCES (2011)
CANCER Sacrifice for survival
Nana-Maria Gruening et al.
NATURE (2011)
Inhibition of Pyruvate Kinase M2 by Reactive Oxygen Species Contributes to Cellular Antioxidant Responses
Dimitrios Anastasiou et al.
SCIENCE (2011)
Targeting Cancer Cell Metabolism: The Combination of Metformin and 2-Deoxyglucose Induces p53-Dependent Apoptosis in Prostate Cancer Cells
Issam Ben Sahra et al.
CANCER RESEARCH (2010)
Metformin is a potent inhibitor of endometrial cancer cell proliferation-implications for a novel treatment strategy
Leigh A. Cantrell et al.
GYNECOLOGIC ONCOLOGY (2010)
AMP-activated Protein Kinase and FoxO Transcription Factors in Dietary Restriction-induced Longevity
Eric L. Greer et al.
INTERNATIONAL SYMPOSIUM ON OLFACTION AND TASTE (2009)
Epidemiological and molecular mechanisms aspects linking obesity and cancer
Felipe Osorio-Costa et al.
ARQUIVOS BRASILEIROS DE ENDOCRINOLOGIA E METABOLOGIA (2009)
Inhibition of p38α unveils an AMPK-FoxO3A axis linking autophagy to cancer-specific metabolism
Fulvio Chiacchiera et al.
AUTOPHAGY (2009)
p38α blockade inhibits colorectal cancer growth in vivo by inducing a switch from HIF1α- to FoxO-dependent transcription
F. Chiacchiera et al.
CELL DEATH AND DIFFERENTIATION (2009)
Cell cycle, CDKs and cancer: a changing paradigm
Marcos Malumbres et al.
NATURE REVIEWS CANCER (2009)
The Effects of Adiponectin and Metformin on Prostate and Colon Neoplasia Involve Activation of AMP-Activated Protein Kinase
Mahvash Zakikhani et al.
CANCER PREVENTION RESEARCH (2008)
p21Cip1 expression is increased in ambient oxygen, compared to estimated physiological (5%) levels in rat muscle precursor cell culture
S. J. Lees et al.
CELL PROLIFERATION (2008)
Metformin attenuates the stimulatory effect of a high-energy diet on in vivo LLC1 carcinoma growth
Carolyn Algire et al.
ENDOCRINE-RELATED CANCER (2008)
FOXO3a mediates the cytotoxic effects of cisplatin in colon cancer cells
Silvia Fernandez de Mattos et al.
MOLECULAR CANCER THERAPEUTICS (2008)
The BCL-2 protein family: opposing activities that mediate cell death
Richard J. Youle et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2008)
The antidiabetic drug metformin exerts an antitumoral effect in vitro and in vivo through a decrease of cyclin D1 level
I. Ben Sahra et al.
ONCOGENE (2008)
Many forks in the path: cycling with FoxO
K. K. Ho et al.
ONCOGENE (2008)
Therapeutic Starvation and Autophagy in Prostate Cancer: A New Paradigm for Targeting Metabolism in Cancer Therapy
Robert S. DiPaola et al.
PROSTATE (2008)
Insulin and insulin-like growth factor signalling in neoplasia
Michael Pollak
NATURE REVIEWS CANCER (2008)
A central role for neuronal adenosine 5'-monophosphate-activated protein kinase in cancer-induced anorexia
Eduardo R. Ropelle et al.
ENDOCRINOLOGY (2007)
The energy sensor AMP-activated protein kinase directly regulates the mammalian FOXO3 transcription factor
Eric L. Greer et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Systemic treatment with the antidiabetic drug metformin selectively impairs p53-deficient tumor cell growth
Monica Buzzai et al.
CANCER RESEARCH (2007)
The regulation of cyclin D1 degradation: roles in cancer development and the potential for therapeutic invention
John P. Alao
MOLECULAR CANCER (2007)
The energy sensing LKB1-AMPK pathway regulates p27kip1 phosphorylation mediating the decision to enter autophagy or apoptosis
Jiyong Liang et al.
NATURE CELL BIOLOGY (2007)
FoxOs are lineage-restricted redundant tumor suppressors and regulate endothelial cell homeostasis
Ji-Hye Paik et al.
CELL (2007)
Angiotensin II cell signaling: physiological and pathological effects in the cardiovascular system
Puja K. Mehta et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2007)
Metformin is an AMP kinase-dependent growth inhibitor for breast cancer cells
Mahvash Zakikhani et al.
CANCER RESEARCH (2006)
Current development of mTOR inhibitors as anticancer agents
Sandrine Faivre et al.
NATURE REVIEWS DRUG DISCOVERY (2006)
Identification of a tumour suppressor network opposing nuclear Akt function
Lloyd C. Trotman et al.
NATURE (2006)
Increased cancer-related mortality for patients with type 2 diabetes who use sulforrylureas or insulin
SL Bowker et al.
DIABETES CARE (2006)
An expanding role for mTOR in cancer
DA Guertin et al.
TRENDS IN MOLECULAR MEDICINE (2005)
Metformin and reduced risk of cancer in diabetic patients
JMM Evans et al.
BMJ-BRITISH MEDICAL JOURNAL (2005)
AMP-activated protein kinase: Ancient energy gauge provides clues to modern understanding of metabolism
BB Kahn et al.
CELL METABOLISM (2005)
IκB kinase promotes tumorigenesis through inhibition of forkhead FOXO3a
MCT Hu et al.
CELL (2004)
Integration of Smad and Forkhead pathways in the control of neuroepithelial and glioblastoma cell proliferation
J Seoane et al.
CELL (2004)
Long-lived Drosophila with overexpressed dFOXO in adult fat body
ME Giannakou et al.
SCIENCE (2004)
Drosophila dFOXO controls lifespan and regulates insulin signalling in brain and fat body
DS Hwangbo et al.
NATURE (2004)
A comparison of the effects of thiazolidinediones and metformin on metabolic control in patients with type 2 diabetes mellitus
J Seufert et al.
CLINICAL THERAPEUTICS (2004)
Metformin - New understandings, new uses
RS Hundal et al.
DRUGS (2003)
The Bax/Bcl-2 ratio determines the susceptibility of human melanoma cells to CD95/Fas-mediated apoptosis
M Raisova et al.
JOURNAL OF INVESTIGATIVE DERMATOLOGY (2001)
Sphingosine generation, cytochrome c release, and activation of caspase-7 in doxorubicin-induced apoptosis of MCF7 breast adenocarcinoma cells
O Cuvillier et al.
CELL DEATH AND DIFFERENTIATION (2001)
Signal transduction by the JNK group of MAP kinases
RJ Davis
CELL (2000)
Expression of the pro-apoptotic Bcl-2 family member Bim is regulated by the forkhead transcription factor FKHR-L1
PF Dijkers et al.
CURRENT BIOLOGY (2000)
Mitochondrial control of cell death
G Kroemer et al.
NATURE MEDICINE (2000)
分享论文
