相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。4-hydroxytamoxifen leads to PrPSc clearance by conveying both PrPC and PrPSc to lysosomes independently of autophagy
Ludovica Marzo et al.
JOURNAL OF CELL SCIENCE (2013)
Characterizing antiprion compounds based on their binding properties to prion proteins: Implications as medical chaperones
Yuji O. Kamatari et al.
PROTEIN SCIENCE (2013)
Nonspecific Prion Protein-Nucleic Acid Interactions Lead to Different Aggregates and Cytotoxic Species
Bruno Macedo et al.
BIOCHEMISTRY (2012)
Prion inhibition with multivalent PrPSc binding compounds
Charles E. Mays et al.
BIOMATERIALS (2012)
Antibacterial activity of chalcones, hydrazones and oxadiazoles against methicillin-resistant Staphylococcus aureus
Thais Moreira Osorio et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2012)
Activity of novel quinoxaline-derived chalcones on in vitro glioma cell proliferation
Tania R. Mielcke et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2012)
Synthesis, Biological Evaluation, And Molecular Modeling of Chalcone Derivatives As Potent Inhibitors of Mycobacterium tuberculosis Protein Tyrosine Phosphatases (PtpA and PtpB)
Louise Domeneghini Chiaradia et al.
JOURNAL OF MEDICINAL CHEMISTRY (2012)
New generation QuIC assays for prion seeding activity
Christina D. Orru et al.
PRION (2012)
Isolation of phosphatidylethanolamine as a solitary cofactor for prion formation in the absence of nucleic acids
Nathan R. Deleault et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Avogadro: an advanced semantic chemical editor, visualization, and analysis platform
Marcus D. Hanwell et al.
JOURNAL OF CHEMINFORMATICS (2012)
A Survey of Antiprion Compounds Reveals the Prevalence of Non-PrP Molecular Targets
Guillaume Poncet-Montange et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
SwissDock, a protein-small molecule docking web service based on EADock DSS
Aurelien Grosdidier et al.
NUCLEIC ACIDS RESEARCH (2011)
Synthesis and anti-prion activity evaluation of aminoquinoline analogues
Bruno Macedo et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2010)
PrP interactions with nucleic acids and glycosaminoglycans in function and disease
Jerson L. Silva et al.
FRONTIERS IN BIOSCIENCE-LANDMARK (2010)
Biochemical Evaluation of a Series of Synthetic Chalcone and Hydrazide Derivatives as Novel Inhibitors of Cruzain from Trypanosoma cruzi
Deise M. Borchhardt et al.
JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY (2010)
Autophagy gone awry in neurodegenerative diseases
Esther Wong et al.
NATURE NEUROSCIENCE (2010)
Protein aggregation diseases: pathogenicity and therapeutic perspectives
Adriano Aguzzi et al.
NATURE REVIEWS DRUG DISCOVERY (2010)
Rapid End-Point Quantitation of Prion Seeding Activity with Sensitivity Comparable to Bioassays
Jason M. Wilham et al.
PLOS PATHOGENS (2010)
Getting a Grip on Prions: Oligomers, Amyloids, and Pathological Membrane Interactions
Byron Caughey et al.
ANNUAL REVIEW OF BIOCHEMISTRY (2009)
Variety of Antiprion Compounds Discovered through an In Silico Screen Based on Cellular-Form Prion Protein Structure: Correlation between Antiprion Activity and Binding Affinity
Junji Hosokawa-Muto et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2009)
Blind Docking of 260 Protein-Ligand Complexes with EADock 2.0
Aurelien Grosdidier et al.
JOURNAL OF COMPUTATIONAL CHEMISTRY (2009)
Safety and efficacy of quinacrine in human prion disease (PRION-1 study): a patient-preference trial
John Collinge et al.
LANCET NEUROLOGY (2009)
Synthetic chalcones as efficient inhibitors of Mycobacterium tuberculosis protein tyrosine phosphatase PtpA
Louise Domeneghini Chiaradia et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2008)
Prions and transmissible spongiform encephalopathy (TSE) chemotherapeutics: A common mechanism for anti-TSE compounds?
B. Caughey et al.
ACCOUNTS OF CHEMICAL RESEARCH (2006)
Similar structure-activity relationships of quinoline derivatives for antiprion and antimalarial effects
Ralf Klingenstein et al.
JOURNAL OF MEDICINAL CHEMISTRY (2006)
Potent antiscrapie activities of degenerate phosphorothioate oligonucleotides
DA Kocisko et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2006)
Mefloquine, an antimalaria drug with antiprion activity in vitro, lacks activity in vivo
DA Kocisko et al.
JOURNAL OF VIROLOGY (2006)
A systematic review of prion therapeutics in experimental models
Clare R. Trevitt et al.
BRAIN (2006)
Modulation of prion protein oligomerization, aggregation, and β-sheet conversion by 4,4′-dianilino-1,1′-binaphthyl-5,5′-sulfonate (bis-ANS)
Y Cordeiro et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Quinoline derivatives are therapeutic candidates for transmissible spongiform encephalopathies
I Murakami-Kubo et al.
JOURNAL OF VIROLOGY (2004)
Prion diseases - Close to effective therapy?
NR Cashman et al.
NATURE REVIEWS DRUG DISCOVERY (2004)
New predictors for several ADME/Tox properties: Aqueous solubility, human oral absorption, and Ames genotoxicity using topological descriptors
Joseph R. Votano et al.
MOLECULAR DIVERSITY (2004)
New inhibitors of scrapie-associated prion protein formation in a library of 2,000 drugs and natural products
DA Kocisko et al.
JOURNAL OF VIROLOGY (2003)
Molecular and clinical classification of human prion disease
JD Wadsworth et al.
BRITISH MEDICAL BULLETIN (2003)
Quinacrine does not prolong survival in a murine Creutzfeldt-Jakob disease model
SJ Collins et al.
ANNALS OF NEUROLOGY (2002)
DNA converts cellular prion protein into the β-sheet conformation and inhibits prion peptide aggregation
Y Cordeiro et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Acridine and phenothiazine derivatives as pharmacotherapeutics for prion disease
C Korth et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Lysosomotropic agents and cysteine protease inhibitors inhibit scrapie-associated prion protein accumulation
K Doh-Ura et al.
JOURNAL OF VIROLOGY (2000)