相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Metformin prevents liver tumorigenesis induced by high-fat diet in C57Bl/6 mice
K. Tajima et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2013)
Disruption of the Cereblon Gene Enhances Hepatic AMPK Activity and Prevents High-Fat Diet-Induced Obesity and Insulin Resistance in Mice
Kwang Min Lee et al.
DIABETES (2013)
Adipocytes Modulate the Phenotype of Human Macrophages through Secreted Lipids
Inge R. Klein-Wieringa et al.
JOURNAL OF IMMUNOLOGY (2013)
Disruption of inducible 6-phosphofructo-2-kinase impairs the suppressive effect of PPARγ activation on diet-induced intestine inflammatory response
Xin Guo et al.
JOURNAL OF NUTRITIONAL BIOCHEMISTRY (2013)
Gly482Ser mutation impairs the effects of peroxisome proliferator-activated receptor γ coactivator-1α on decreasing fat deposition and stimulating phosphoenolpynivate carboxykinase expression in hepatocytes
Yanming Chen et al.
NUTRITION RESEARCH (2013)
Discovery of P1736, a Novel Antidiabetic Compound That Improves Peripheral Insulin Sensitivity in Mice Models
Jessy Anthony et al.
PLOS ONE (2013)
Targeted Overexpression of Inducible 6-Phosphofructo-2-kinase in Adipose Tissue Increases Fat Deposition but Protects against Diet-induced Insulin Resistance and Inflammatory Responses
Yuqing Huo et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Palmitoleate Induces Hepatic Steatosis but Suppresses Liver Inflammatory Response in Mice
Xin Guo et al.
PLOS ONE (2012)
Metformin Prevents and Reverses Inflammation in a Non-Diabetic Mouse Model of Nonalcoholic Steatohepatitis
Yuki Kita et al.
PLOS ONE (2012)
AMPK Phosphorylates and Inhibits SREBP Activity to Attenuate Hepatic Steatosis and Atherosclerosis in Diet-Induced Insulin-Resistant Mice
Yu Li et al.
CELL METABOLISM (2011)
Differential Lipid Partitioning Between Adipocytes and Tissue Macrophages Modulates Macrophage Lipotoxicity and M2/M1 Polarization in Obese Mice
Xavier Prieur et al.
DIABETES (2011)
Evolution of Inflammation in Nonalcoholic Fatty Liver Disease: The Multiple Parallel Hits Hypothesis
Herbert Tilg et al.
HEPATOLOGY (2010)
Disruption of Inducible 6-Phosphofructo-2-kinase Ameliorates Diet-induced Adiposity but Exacerbates Systemic Insulin Resistance and Adipose Tissue Inflammatory Response
Yuqing Huo et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Involvement of Inducible 6-Phosphofructo-2-kinase in the Anti-diabetic Effect of Peroxisome Proliferator-activated Receptor γ Activation in Mice
Xin Guo et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Metformin inhibits hepatic gluconeogenesis in mice independently of the LKB1/AMPK pathway via a decrease in hepatic energy state
Marc Foretz et al.
JOURNAL OF CLINICAL INVESTIGATION (2010)
NASH Thiazolidinediones for NASH-one pill doesn't fix everything
Brent A. Neuschwander-Tetri
NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2010)
Metformin and Insulin Suppress Hepatic Gluconeogenesis through Phosphorylation of CREB Binding Protein
Ling He et al.
CELL (2009)
AMPK: An Emerging Drug Target for Diabetes and the Metabolic Syndrome
Bei B. Zhang et al.
CELL METABOLISM (2009)
Immature Myeloid Cells Induced by a High-Fat Diet Contribute to Liver Inflammation
Zhong-bin Deng et al.
HEPATOLOGY (2009)
Palmitate Induces Insulin Resistance in H4IIEC3 Hepatocytes through Reactive Oxygen Species Produced by Mitochondria
Seiji Nakamura et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Alternative M2 activation of Kupffer cells by PPARδ ameliorates obesity-induced insulin resistance
Justin I. Odegaard et al.
CELL METABOLISM (2008)
Peroxisome proliferator-activated receptor γ activation promotes infiltration of alternatively activated macrophages into adipose tissue
Rinke Stienstra et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Palmitic acid induces production of proinflammatory cytokine interleukin-8 from hepatocytes
Swati joshi-Barve et al.
HEPATOLOGY (2007)
Macrophage-specific PPARγ controls alternative activation and improves insulin resistance
Justin I. Odegaard et al.
NATURE (2007)
Overexpression of monocyte chemoattractant protein-1 in adipose tissues causes macrophage recruitment and insulin resistance
Nozomu Kamei et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Perturbation of glucose flux in the liver by decreasing F26P2 levels causes hepatic insulin resistance and hyperglycemia
Chaodong Wu et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2006)
Global gene expression analysis in liver of obese diabetic db/db mice treated with metformin
M. Heishi et al.
DIABETOLOGIA (2006)
Metformin counters the insulin-induced suppression of fatty acid oxidation and stimulation of triacylglycerol storage in rodent skeletal muscle
Cheryl A. Collier et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2006)
NAFLD, obesity, and bariatric surgery
Paul Angulo
GASTROENTEROLOGY (2006)
Nonalcoholic fatty liver disease: From steatosis to cirrhosis
GC Farrell et al.
HEPATOLOGY (2006)
Nonalcoholic fatty liver disease and risk of future cardiovascular events among type 2 diabetic patients
G Targher et al.
DIABETES (2005)
Enhancing hepatic glycolysis reduces obesity: Differential effects on lipogenesis depend on site of glycolytic modulation
CD Wu et al.
CELL METABOLISM (2005)
Mechanisms of Disease:: adipocytokines and visceral adipose tissue -: emerging role in nonalcoholic fatty liver disease
A Schäffler et al.
NATURE CLINICAL PRACTICE GASTROENTEROLOGY & HEPATOLOGY (2005)
A randomized controlled trial of metformin versus vitamin E or prescriptive diet in nonalcoholic fatty liver disease
E Bugianesi et al.
AMERICAN JOURNAL OF GASTROENTEROLOGY (2005)
Treatment strategies in nonalcoholic fatty liver disease
H Tilg et al.
NATURE CLINICAL PRACTICE GASTROENTEROLOGY & HEPATOLOGY (2005)
Local and systemic insulin resistance resulting from hepatic activation of IKK-β and NF-κB
DS Cai et al.
NATURE MEDICINE (2005)
Hepatic gene expression profiles in a long-term high-fat diet-induced obesity mouse model
S Kim et al.
GENE (2004)
Molecular mediators of hepatic steatosis and liver injury
JD Browning et al.
JOURNAL OF CLINICAL INVESTIGATION (2004)
AMP-activated protein kinase is required for the lipid-lowering effect of metformin in insulin-resistant human HepG2 cells
MW Zang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Fatty liver in type 2 diabetes mellitus: relation to regional adiposity, fatty acids, and insulin resistance
DE Kelley et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2003)
Metformin in non-alcoholic steatohepatitis
G Marchesini et al.
LANCET (2001)
Overexpression of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase in mouse liver lowers blood glucose by suppressing hepatic glucose production
CD Wu et al.
JOURNAL OF CLINICAL INVESTIGATION (2001)