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Nuclear signalling by tumour-associated antigen EpCAM
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EpCAM Is Involved in Maintenance of the Murine Embryonic Stem Cell Phenotype
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Glycosylation is crucial for stability of tumour and cancer stem cell antigen EpCAM
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Frequent high-level expression of the immunotherapeutic target Ep-CAM in colon, stomach, prostate and lung cancers
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BRITISH JOURNAL OF CANCER (2006)
The cell-cell adhesion molecule EpCAM interacts directly with the tight junction protein claudin-7
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Loss of Ep-CAM (CO17-1A) expression predicts survival in patients with gastric cancer
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BRITISH JOURNAL OF CANCER (2005)
EpCAM is overexpressed in breast cancer and is a potential target for breast cancer gene therapy
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High Ep-CAM expression is associated with poor prognosis in node-positive breast cancer
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The carcinoma-associated antigen EpCAM upregulates c-myc and induces cell proliferation
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γ-secretase:: proteasome of the membrane?
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RIPped out by presenilin-dependent γ-secretase
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TACE/ADAM-17 enzymatic activity is increased in response to cellular stimulation
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BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2003)
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Mammalian numb proteins promote notch1 receptor ubiquitination and degradation of the notch1 intracellular domain
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Presenilin-dependent intramembrane proteolysis of CD44 leads to the liberation of its intracellular domain and the secretion of an Aβ-like peptide
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The protease inhibitor, MG132, blocks maturation of the amyloid precursor protein Swedish mutant preventing cleavage by β-secretase
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Tumor necrosis factor-α-converting enzyme is required for cleavage of erbB4/HER4
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