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注意:仅列出部分参考文献,下载原文获取全部文献信息。Therapeutic potential of Galectin-9 in human disease
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MEDICINAL RESEARCH REVIEWS (2013)
Serum galectin-9 levels are elevated in the patients with type 2 diabetes and chronic kidney disease
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Galectin-9 induced by dietary synbiotics is involved in suppression of allergic symptoms in mice and humans
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Tim-3 is an inducible human natural killer cell receptor that enhances interferon gamma production in response to galectin-9
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Galectin-9 binding to Tim-3 renders activated human CD4+ T cells less susceptible to HIV-1 infection
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Galectin-9 suppresses Th17 cell development in an IL-2-dependent but Tim-3-independent manner
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Tim-3, a negative regulator of anti-tumor immunity
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Galectin-9 and T Cell Immunoglobulin Mucin-3 Pathway Is a Therapeutic Target for Type 1 Diabetes
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Galectin-9 ameliorates herpes simplex virus-induced inflammation through apoptosis
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Coexpression of Tim-3 and PD-1 identifies a CD8+ T-cell exhaustion phenotype in mice with disseminated acute myelogenous leukemia
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BLOOD (2011)
Tim-3 ligand galectin-9 reduces IL-17 level and accelerates Klebsiella pneumoniae infection
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Galectin-9 administration ameliorates CVB3 induced myocarditis by promoting the proliferation of regulatory T cells and alternatively activated Th2 cells
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Galectin-9 regulates T helper cell function independently of Tim-3
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Selective elimination of pathogenic synovial fluid T-cells from Rheumatoid Arthritis and Juvenile Idiopathic Arthritis by targeted activation of Fas-apoptotic signaling
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IMMUNOLOGY LETTERS (2011)
Galectin-9 binding to cell surface protein disulfide isomerase regulates the redox environment to enhance T-cell migration and HIV entry
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Galectin-9 expands unique macrophages exhibiting plasmacytoid dendritic cell-like phenotypes that activate NK cells in tumor-bearing mice
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CLINICAL IMMUNOLOGY (2009)
Galectin-9 ameliorates immune complex-induced arthritis by regulating FcγR expression on macrophages
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Attenuation of Th1 response through galectin-9 and T-cell Ig mucin 3 interaction inhibits autoimmune diabetes in NOD mice
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EUROPEAN JOURNAL OF IMMUNOLOGY (2009)
Tim-3-Galectin-9 pathway involves the suppression induced by CD4+CD25+ regulatory T cells
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Galectin-9 Is a High Affinity IgE-binding Lectin with Anti-allergic Effect by Blocking IgE-Antigen Complex Formation
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Galectin-9 suppresses the generation of Th17, promotes the induction of regulatory T cells, and regulates experimental autoimmune arthritis
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CLINICAL IMMUNOLOGY (2008)
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Galectin-9 Increases Tim-3+ Dendritic Cells and CD8+ T Cells and Enhances Antitumor Immunity via Galectin-9-Tim-3 Interactions
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Galectin-9 inhibits CD44-hyaluronan interaction and suppresses a murine model of allergic asthma
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Characterization of galectin-9-induced death of Jurkat T cells
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The Tim-3 ligand galectin-9 negatively regulates T helper type 1 immunity
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Galectin-9 induces maturation of human monocyte-derived dendritic cells
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JOURNAL OF IMMUNOLOGY (2005)
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Galectin-9 induces apoptosis through the calcium-calpain-caspase-1 pathway
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