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Tamas Balla et al.
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Douglas J. Demian et al.
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Sam Michael et al.
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Brian Y. Feng et al.
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Z. A. Knight et al.
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BJ Eastwood et al.
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Atsuo T. Sasaki et al.
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ZA Knight et al.
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KA Lamia et al.
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K Fuchikami et al.
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Substrate competitive inhibitors of IGF-1 receptor kinase
G Blum et al.
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JB Morris et al.
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