相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Neutralizing Epitopes in the Membrane-Proximal External Region of HIV-1 gp41 Are Influenced by the Transmembrane Domain and the Plasma Membrane
Marinieve Montero et al.
JOURNAL OF VIROLOGY (2012)
Structural and genetic basis for development of broadly neutralizing influenza antibodies
Daniel Lingwood et al.
NATURE (2012)
Subunit organization of the membrane-bound HIV-1 envelope glycoprotein trimer
Youdong Mao et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2012)
Targeting Antibody Responses to the Membrane Proximal External Region of the Envelope Glycoprotein of Human Immunodeficiency Virus
Donatien Kamdem Toukam et al.
PLOS ONE (2012)
Prime boost vaccination approaches with different conjugates of a new HIV-1 gp41 epitope encompassing the membrane proximal external region induce neutralizing antibodies in mice
Mingkui Zhou et al.
VACCINE (2012)
Structure-guided Alterations of the gp41-directed HIV-1 Broadly Neutralizing Antibody 2F5 Reveal New Properties Regarding its Neutralizing Function
Javier Guenaga et al.
PLOS PATHOGENS (2012)
Reactivity profiles of broadly neutralizing anti-HIV-1 antibodies are distinct from those of pathogenic autoantibodies
Harvir Singh et al.
AIDS (2011)
Interaction of Anti-HIV Type 1 Antibody 2F5 with Phospholipid Bilayers and Its Relevance for the Mechanism of Virus Neutralization
Ruben Maeso et al.
AIDS RESEARCH AND HUMAN RETROVIRUSES (2011)
Cross-Reactive HIV-1-Neutralizing Human Monoclonal Antibodies Identified from a Patient with 2F5-Like Antibodies
Zhongyu Zhu et al.
JOURNAL OF VIROLOGY (2011)
Antibody mechanics on a membrane-bound HIV segment essential for GP41-targeted viral neutralization
Mikyung Kim et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2011)
Comparison of Antibody Repertoires Produced by HIV-1 Infection, Other Chronic and Acute Infections, and Systemic Autoimmune Disease
Felix Breden et al.
PLOS ONE (2011)
Heterologous Epitope-Scaffold Prime:Boosting Immuno-Focuses B Cell Responses to the HIV-1 gp41 2F5 Neutralization Determinant
Javier Guenaga et al.
PLOS ONE (2011)
Induction of HIV Neutralizing Antibodies against the MPER of the HIV Envelope Protein by HA/gp41 Chimeric Protein-Based DNA and VLP Vaccines
Ling Ye et al.
PLOS ONE (2011)
Induction of Antibodies in Rhesus Macaques That Recognize a Fusion-Intermediate Conformation of HIV-1 gp41
S. Moses Dennison et al.
PLOS ONE (2011)
Maturation-Induced Cloaking of Neutralization Epitopes on HIV-1 Particles
Amanda S. Joyner et al.
PLOS PATHOGENS (2011)
Interactions between Lipids and Human Anti-HIV Antibody 4E10 Can Be Reduced without Ablating Neutralizing Activity
Hengyu Xu et al.
JOURNAL OF VIROLOGY (2010)
Broadly Neutralizing Monoclonal Antibodies 2F5 and 4E10 Directed against the Human Immunodeficiency Virus Type 1 gp41 Membrane-Proximal External Region Protect against Mucosal Challenge by Simian-Human Immunodeficiency Virus SHIVBa-L
Ann J. Hessell et al.
JOURNAL OF VIROLOGY (2010)
Relationship between Antibody 2F5 Neutralization of HIV-1 and Hydrophobicity of Its Heavy Chain Third Complementarity-Determining Region
Gilad Ofek et al.
JOURNAL OF VIROLOGY (2010)
Ablation of the Complementarity-Determining Region H3 Apex of the Anti-HIV-1 Broadly Neutralizing Antibody 2F5 Abrogates Neutralizing Capacity without Affecting Core Epitope Binding
Jean-Philippe Julien et al.
JOURNAL OF VIROLOGY (2010)
Scaffolding to build a rational vaccine design strategy
Dennis R. Burton
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Aromatic residues at the edge of the antibody combining site facilitate viral glycoprotein recognition through membrane interactions
Erin M. Scherer et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Elicitation of structure-specific antibodies by epitope scaffolds
Gilad Ofek et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Epitope specificities of broadly neutralizing plasmas from HIV-1 infected subjects
D. Noah Sather et al.
VACCINE (2010)
Neutralizing antibodies induced by liposomal HIV-1 glycoprotein 41 peptide simultaneously bind to both the 2F5 or 4E10 epitope and lipid epitopes
Gary R. Matyas et al.
AIDS (2009)
Lipid binding properties of 4E10, 2175, and WR304 monoclonal antibodies that neutralize HIV-1
Gary R. Matyas et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2009)
Structural Constraints Imposed by the Conserved Fusion Peptide on the HIV-1 gp41 Epitope Recognized by the Broadly Neutralizing Antibody 2F5
Igor de la Arada et al.
JOURNAL OF PHYSICAL CHEMISTRY B (2009)
Analysis of Neutralization Specificities in Polyclonal Sera Derived from Human Immunodeficiency Virus Type 1-Infected Individuals
Yuxing Li et al.
JOURNAL OF VIROLOGY (2009)
Crystallographic Definition of the Epitope Promiscuity of the Broadly Neutralizing Anti-Human Immunodeficiency Virus Type 1 Antibody 2F5: Vaccine Design Implications
Steve Bryson et al.
JOURNAL OF VIROLOGY (2009)
In Vivo gp41 Antibodies Targeting the 2F5 Monoclonal Antibody Epitope Mediate Human Immunodeficiency Virus Type 1 Neutralization Breadth
Xiaoying Shen et al.
JOURNAL OF VIROLOGY (2009)
Stable Docking of Neutralizing Human Immunodeficiency Virus Type 1 gp41 Membrane-Proximal External Region Monoclonal Antibodies 2F5 and 4E10 Is Dependent on the Membrane Immersion Depth of Their Epitope Regions
S. Moses Dennison et al.
JOURNAL OF VIROLOGY (2009)
Broad Neutralization of Human Immunodeficiency Virus Type 1 Mediated by Plasma Antibodies against the gp41 Membrane Proximal External Region
Elin S. Gray et al.
JOURNAL OF VIROLOGY (2009)
Broadly neutralizing anti-HIV-1 antibodies disrupt a hinge-related function of gp41 at the membrane interface
Likai Song et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Role of HIV membrane in neutralization by two broadly neutralizing antibodies
S. Munir Alam et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Maturation Pathways of Cross-Reactive HIV-1 Neutralizing Antibodies
Xiaodong Xiao et al.
VIRUSES-BASEL (2009)
4E10 and 2F5 monoclonal antibodies: binding specificities to phospholipids, tolerance, and clinical safety issues
Carl R. Alving
AIDS (2008)
Interfacial pre-transmembrane domains in viral proteins promoting membrane fusion and fission
Maier Lorizate et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2008)
HIV-1 broadly neutralizing antibody extracts its epitope from a kinked gp41 ectodomain region on the viral membrane
Zhen-Yu J. Sun et al.
IMMUNITY (2008)
Structural Details of HIV-1 Recognition by the Broadly Neutralizing Monoclonal Antibody 2F5: Epitope Conformation, Antigen-Recognition Loop Mobility, and Anion-Binding Site
Jean-Philippe Julien et al.
JOURNAL OF MOLECULAR BIOLOGY (2008)
The broadly neutralizing anti-human immunodeficiency virus type 1 4E10 monoclonal antibody is better adapted to membrane-bound epitope recognition and blocking than 2F5
Nerea Huarte et al.
JOURNAL OF VIROLOGY (2008)
Importance of the membrane-perturbing properties of the membrane-proximal external region of human immunodeficiency virus type 1 gp41 to viral fusion
Sundararn A. Vishwanathan et al.
JOURNAL OF VIROLOGY (2008)
The challenges of eliciting neutralizing antibodies to HIV-1 and to influenza virus
Gunilla B. Karlsson Hedestam et al.
NATURE REVIEWS MICROBIOLOGY (2008)
The membrane-proximal external region of the human immunodeficiency virus type 1 envelope: Dominant site of antibody neutralization and target for vaccine design
Marinieve Montero et al.
MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS (2008)
Difficulties in eliciting broadly neutralizing anti-HIV antibodies are not explained by cardiolipin autoreactivity
Erin M. Scherer et al.
AIDS (2007)
Reassessment of autoreactivity of the broadly neutralizing HIV antibodies 4E10 and 2F5 and retrospective analysis of clinical safety data
Brigitta Vcelar et al.
AIDS (2007)
Structure and plasticity of the human immunodeficiency virus gp41 fusion domain in lipid micelles and bilayers
Yinling Li et al.
BIOPHYSICAL JOURNAL (2007)
Exposure of the membrane-proximal external region of HIV-1 gp41 in the course of HIV-1 envelope glycoprotein-mediated fusion
Antony S. Dimitrov et al.
BIOCHEMISTRY (2007)
Recognition and blocking of HIV-1 gp41 pre-transmembrane sequence by monoclonal 4E10 antibody in a raft-like membrane environment
Maier Lorizate et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Structural analysis and assembly of the HIV-1 gp41 amino-terminal fusion peptide and the pretransmembrane amphipathic-at-interface sequence
Maier Lorizate et al.
BIOCHEMISTRY (2006)
UV resonance Raman investigation of a 310-helical peptide reveals a rough energy landscape
Zeeshan Ahmed et al.
BIOCHEMISTRY (2006)
Membrane-transferring sequences of the HIV-1 gp41 ectodomain assemble into an immunogenic complex
Maier Lorizate et al.
JOURNAL OF MOLECULAR BIOLOGY (2006)
The membrane-proximal external region of HIV-1 gp41: a vaccine target worth exploring
MB Zwick
AIDS (2005)
The 2F5 epitope is helical in the HIV-1 entry inhibitor T-20
Z Biron et al.
BIOCHEMISTRY (2005)
Cardiolipin polyspecific autoreactivity in two broadly neutralizing HIV-1 antibodies
BF Haynes et al.
SCIENCE (2005)
Conformational constraints imposed on a pan-neutralizing HIV-1 antibody epitope result in increased antigenicity but not neutralizing response
J Ho et al.
VACCINE (2005)
Anti-human immunodeficiency virus type 1 (HIV-1) antibodies 2F5 and 4E10 require surprisingly few crucial residues in the membrane-proximal external region of glycoprotein gp41 to neutralize HIV-1
MB Zwick et al.
JOURNAL OF VIROLOGY (2005)
The long third complementarity-determining region of the heavy chain is important in the activity of the broadly neutralizing anti-human immunodeficiency virus type 1 antibody 2F5
MB Zwick et al.
JOURNAL OF VIROLOGY (2004)
Structure and mechanistic analysis of the anti-human immunodeficiency virus type 1 antibody 2F5 in complex with its gp41 epitope
G Ofek et al.
JOURNAL OF VIROLOGY (2004)
Structural analysis of the epitope of the Anti-HIV antibody 2F5 sheds light into its mechanism of neutralization and HIV fusion
G Barbato et al.
JOURNAL OF MOLECULAR BIOLOGY (2003)
Therapeutic potential of neutralizing antibodies in the treatment of HIV-1 infection
G Stiegler et al.
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY (2003)
HIV-1 vaccine development: Constrained peptide immunogens show improved binding to the anti-HIV-1 gp41 MAb
GB McGaughey et al.
BIOCHEMISTRY (2003)
Enhancement of α-helicity in the HIV-1 inhibitory peptide DP178 leads to an increased affinity for human monoclonal antibody 2F5 but does not elicit neutralizing responses in vitro -: Implications for vaccine design
JG Joyce et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
A monomeric 310-helix is formed in water by a 13-residue peptide representing the neutralizing determinant of HIV-1 on gp41
Z Biron et al.
BIOCHEMISTRY (2002)
Structure-affinity relationships in the gp41 ELDKWA epitope for the HIV-1 neutralizing monoclonal antibody 2F5:: effects of side-chain and backbone modifications and conformational constraints
Y Tian et al.
JOURNAL OF PEPTIDE RESEARCH (2002)
A potent cross-clade neutralizing human monoclonal antibody against a novel epitope on gp41 of human immunodeficiency virus type 1
G Stiegler et al.
AIDS RESEARCH AND HUMAN RETROVIRUSES (2001)
Fine definition of the epitope on the gp41 glycoprotein of human immunodeficiency virus type 1 for the neutralizing monoclonal antibody 2F5
CE Parker et al.
JOURNAL OF VIROLOGY (2001)
Antigenicity and immunogenicity of the HIV-1 gp41 epitope ELDKWA inserted into permissive sites of the MalE protein
E Coëffier et al.
VACCINE (2000)
Interactions of the HIV-1 fusion peptide with large unilamellar vesicles and monolayers.: A cryo-TEM and spectroscopic study
A Agirre et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2000)
Membrane interface-interacting sequences within the ectodomain of the human immunodeficiency virus type 1 envelope glycoprotein: Putative role during viral fusion
T Suarez et al.
JOURNAL OF VIROLOGY (2000)