相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。TAK1 Inhibition Promotes Apoptosis in KRAS-Dependent Colon Cancers
Anurag Singh et al.
CELL (2012)
Comprehensive molecular characterization of human colon and rectal cancer
Donna M. Muzny et al.
NATURE (2012)
Hyaluronan-CD44 interactions as potential targets for cancer therapy
Suniti Misra et al.
FEBS JOURNAL (2011)
Somatic variation and cancer: therapies lost in the mix
Andrew V. Biankin et al.
HUMAN GENETICS (2011)
Receptor tyrosine kinases exert dominant control over PI3K signaling in human KRAS mutant colorectal cancers
Hiromichi Ebi et al.
JOURNAL OF CLINICAL INVESTIGATION (2011)
Molecular Genetic Analysis of 103 Sporadic Colorectal Tumours in Czech Patients
Peter Vasovcak et al.
PLOS ONE (2011)
The Temporal Order of Genetic and Pathway Alterations in Tumorigenesis
Moritz Gerstung et al.
PLOS ONE (2011)
Genomic and Biological Characterization of Exon 4 KRAS Mutations in Human Cancer
Manickam Janakiraman et al.
CANCER RESEARCH (2010)
Colorectal Tumors Are Effectively Eradicated by Combined Inhibition of β-Catenin, KRAS, and the Oncogenic Transcription Factor ITF2
Luca Mologni et al.
CANCER RESEARCH (2010)
Galectin-3 Promotes Chronic Activation of K-Ras and Differentiation Block in Malignant Thyroid Carcinomas
Ran Levy et al.
MOLECULAR CANCER THERAPEUTICS (2010)
Small-molecule inhibition of Wnt signaling through activation of casein kinase 1α
Curtis A. Thorne et al.
NATURE CHEMICAL BIOLOGY (2010)
Accumulation of driver and passenger mutations during tumor progression
Ivana Bozic et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Small Molecule Inhibitors of Wnt/β-Catenin/Lef-1 Signaling Induces Apoptosis in Chronic Lymphocytic Leukemia Cells In Vitro and In Vivo
Rajesh Kumar Gandhirajan et al.
NEOPLASIA (2010)
Synthetic Lethal Interaction between Oncogenic KRAS Dependency and STK33 Suppression in Human Cancer Cells
Claudia Scholl et al.
CELL (2009)
A Genome-wide RNAi Screen Identifies Multiple Synthetic Lethal Interactions with the Ras Oncogene
Ji Luo et al.
CELL (2009)
β-Catenin degradation mediated by the CID domain of APC provides a model for the selection of APC mutations in colorectal, desmoid and duodenal tumours
Eva Maria Kohler et al.
HUMAN MOLECULAR GENETICS (2009)
Valproic acid enhances bosutinib cytotoxicity in colon cancer cells
Luca Mologni et al.
INTERNATIONAL JOURNAL OF CANCER (2009)
Intrinsic resistance to the MEK1/2 inhibitor AZD6244 (ARRY-142886) is associated with weak ERKI/2 signalling and/or strong P13K signalling in colorectal cancer cell lines
Kathryn Balmanno et al.
INTERNATIONAL JOURNAL OF CANCER (2009)
Molecular Origins of Cancer: Molecular Basis of Colorectal Cancer.
Sanford D. Markowitz et al.
NEW ENGLAND JOURNAL OF MEDICINE (2009)
Efficacy of pyrvinium pamoate against Cryptosporidium parvum infection in vitro and in a neonatal mouse model
Autumn S. Downey et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2008)
Hyaluronan constitutively regulates activation of COX-2-mediated cell survival activity in intestinal epithelial and colon carcinoma cells
Suniti Misra et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
The T cell factor/β-catenin antagonist PKF115-584 inhibits proliferation of adrenocortical carcinoma cells
Mabrouka Doghman et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2008)
Pyrvinium Targets the Unfolded Protein Response to Hypoglycemia and Its Anti-Tumor Activity Is Enhanced by Combination Therapy
De-Hua Yu et al.
PLOS ONE (2008)
Detection of BRAF V600E mutation by pyrosequencing
Yi Hui Tan et al.
PATHOLOGY (2008)
RAS signaling in colorectal carcinomas through alterations of RAS, RAF, NF1, and/or RASSF1A
Terje Ahlquist et al.
NEOPLASIA (2008)
Orally administered FTS (salirasib) inhibits human pancreatic tumor growth in nude mice
Roni Haklai et al.
CANCER CHEMOTHERAPY AND PHARMACOLOGY (2008)
Oncogene addiction: setting the stage for molecularly targeted cancer therapy
Sreenath V. Sharma et al.
GENES & DEVELOPMENT (2007)
The genomic landscapes of human breast and colorectal cancers
Laura D. Wood et al.
SCIENCE (2007)
Survivin down-regulation plays a crucial role in 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitor-induced apoptosis in cancer
Reiko Kaneko et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Targeting the β-catenin/TCF transcriptional complex in the treatment of multiple myeloma
Kumar Sukhdeo et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Survivin depletion preferentially reduces the survival of activated K-Ras-transformed cells
Aparna V. Sarthy et al.
MOLECULAR CANCER THERAPEUTICS (2007)
Suppression of lung cancer tumor growth in a nude mouse model by the Ras inhibitor salirasib (farnesylthiosalicylic acid)
Adi Zundelevich et al.
MOLECULAR CANCER THERAPEUTICS (2007)
The consensus coding sequences of human breast and colorectal cancers
Tobias Sjoeblom et al.
SCIENCE (2006)
APC and oncogenic KRAS are synergistic in enhancing Wnt signaling in intestinal tumor formation and progression
Klaus-Peter Janssen et al.
GASTROENTEROLOGY (2006)
Loss of Apc allows phenotypic manifestation of the transforming properties of an endogenous K-ras oncogene in vivo
Owen J. Sansom et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
KRASD13 promotes apoptosis of human colorectal tumor cells by ReovirusT3D and oxaliplatin but not by tumor necrosis factor-related apoptosis-inducing ligand
Niels Smakman et al.
CANCER RESEARCH (2006)
Theoretical basis, experimental design, and computerized simulation of synergism and antagonism in drug combination studies
Ting-Chao Chou
PHARMACOLOGICAL REVIEWS (2006)
G protein-coupled lysophosphatidic acid receptors stimulate proliferation of colon cancer cells through the β-catenin pathway
M Yang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Antitumor activity of pyrvinium pamoate, 6-(dimethylamino)-2-[2-(2,5-dimethyl-1-phenyl-1H- pyrrol-3-yl)ethenyl]-1-methyl-quinolinium pamoate salt, showing preferential cytotoxicity during glucose starvation
H Esumi et al.
CANCER SCIENCE (2004)
Different genetic features associated with colon and rectal carcinogenesis
M Frattini et al.
CLINICAL CANCER RESEARCH (2004)
Small-molecule antagonists of the oncogenic Tcf/beta-catenin protein complex
M Lepourcelet et al.
CANCER CELL (2004)
Ral-GTPases: approaching their 15 minutes of fame
LA Feig
TRENDS IN CELL BIOLOGY (2003)
The β-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells
M van de Wetering et al.
CELL (2002)
Hematologic and cytogenetic responses to imatinib mesylate in chronic myelogenous leukemia.
H Kantarjian et al.
NEW ENGLAND JOURNAL OF MEDICINE (2002)
Extensive characterization of genetic alterations in a series of human colorectal cancer cell lines
J Gayet et al.
ONCOGENE (2001)