4.6 Article

Routine Multiplex Mutational Profiling of Melanomas Enables Enrollment in Genotype-Driven Therapeutic Trials

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Oncology

The Impact of Eliminating Socioeconomic and Racial Disparities on Premature Cancer Deaths

Rebecca Siegel et al.

CA-A CANCER JOURNAL FOR CLINICIANS (2011)

Article Medicine, General & Internal

KIT as a Therapeutic Target in Metastatic Melanoma

Richard D. Carvajal et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2011)

Editorial Material Oncology

Biology-Driven Phase II Trials: What Is the Optimal Model for Molecular Selection?

Fabrice Andre et al.

JOURNAL OF CLINICAL ONCOLOGY (2011)

Article Oncology

Prognostic and Clinicopathologic Associations of Oncogenic BRAF in Metastatic Melanoma

Georgina V. Long et al.

JOURNAL OF CLINICAL ONCOLOGY (2011)

Article Medicine, General & Internal

Improved Survival with Vemurafenib in Melanoma with BRAF V600E Mutation

Paul B. Chapman et al.

NEW ENGLAND JOURNAL OF MEDICINE (2011)

Article Biochemistry & Molecular Biology

Dasatinib sensitizes KRAS mutant colorectal tumors to cetuximab

E. F. Dunn et al.

ONCOGENE (2011)

Article Biochemistry & Molecular Biology

Kinase-Dead BRAF and Oncogenic RAS Cooperate to Drive Tumor Progression through CRAF

Sonja J. Heidorn et al.

Article Medicine, Research & Experimental

Rapid targeted mutational analysis of human tumours: a clinical platform to guide personalized cancer medicine

Dora Dias-Santagata et al.

EMBO MOLECULAR MEDICINE (2010)

Meeting Abstract Oncology

Safety and efficacy results from the first-in-human study of the oral MEK 1/2 inhibitor GSK1120212

J. R. Infante et al.

JOURNAL OF CLINICAL ONCOLOGY (2010)

Letter Dermatology

Response to Imatinib Mesylate Depends on the Presence of the V559A-Mutated KIT Oncogene

Patrick Terheyden et al.

JOURNAL OF INVESTIGATIVE DERMATOLOGY (2010)

Editorial Material Medicine, Research & Experimental

Incidence of the V600K mutation among melanoma patients with BRAF mutations, and potential therapeutic response to the specific BRAF inhibitor PLX4032

Jill C. Rubinstein et al.

JOURNAL OF TRANSLATIONAL MEDICINE (2010)

Article Biochemistry & Molecular Biology

Intronic miR-211 Assumes the Tumor Suppressive Function of Its Host Gene in Melanoma

Carmit Levy et al.

MOLECULAR CELL (2010)

Article Multidisciplinary Sciences

RAF inhibitors transactivate RAF dimers and ERK signalling in cells with wild-type BRAF

Poulikos I. Poulikakos et al.

NATURE (2010)

Article Multidisciplinary Sciences

RAF inhibitors prime wild-type RAF to activate the MAPK pathway and enhance growth

Georgia Hatzivassiliou et al.

NATURE (2010)

Article Multidisciplinary Sciences

Melanomas acquire resistance toB-RAF(V600E) inhibition by RTK or N-RAS upregulation

Ramin Nazarian et al.

NATURE (2010)

Article Medicine, General & Internal

Inhibition of Mutated, Activated BRAF in Metastatic Melanoma

Keith T. Flaherty et al.

NEW ENGLAND JOURNAL OF MEDICINE (2010)

Article Medicine, General & Internal

Mutations in GNA11 in Uveal Melanoma.

Catherine D. Van Raamsdonk et al.

NEW ENGLAND JOURNAL OF MEDICINE (2010)

Article Dermatology

Melanoma from bench to bedside: meeting report from the 6th international melanoma congress

D. E. Fisher et al.

Pigment Cell & Melanoma Research (2010)

Article Multidisciplinary Sciences

Frequent somatic mutations of GNAQ in uveal melanoma and blue naevi

Catherine D. Van Raamsdonk et al.

NATURE (2009)

Article Oncology

KIT Gene Mutations and Copy Number in Melanoma Subtypes

Carol Beadling et al.

CLINICAL CANCER RESEARCH (2008)

Article Oncology

Imatinib Targeting of KIT-Mutant Oncoprotein in Melanoma

Xiaofeng Jiang et al.

CLINICAL CANCER RESEARCH (2008)

Article Biochemistry & Molecular Biology

Dipeptidyl peptidase IV (DPPIV), a candidate tumor suppressor gene in melanomas is silenced by promoter methylation

Carolyn McGuinness et al.

FRONTIERS IN BIOSCIENCE-LANDMARK (2008)

Article Oncology

Major response to imatinib mesylate in KIT-mutated melanoma

F. Stephen Hodi et al.

JOURNAL OF CLINICAL ONCOLOGY (2008)

Article Multidisciplinary Sciences

Discovery of a selective inhibitor of oncogenic B-Raf kinase with potent antimelanoma activity

James Tsai et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)

Article Oncology

Somatic activation of KIT in distinct subtypes of melanoma

John A. Curtin et al.

JOURNAL OF CLINICAL ONCOLOGY (2006)

Article Medicine, General & Internal

Distinct sets of genetic alterations in melanoma

JA Curtin et al.

NEW ENGLAND JOURNAL OF MEDICINE (2005)

Article Dermatology

Genetic interaction between NRAS and BRAF mutations and PTEN/MMAC1 inactivation in melanoma

H Tsao et al.

JOURNAL OF INVESTIGATIVE DERMATOLOGY (2004)

Article Oncology

Determinants of BRAF mutations in primary melanomas

JL Maldonado et al.

JOURNAL OF THE NATIONAL CANCER INSTITUTE (2003)

Article Multidisciplinary Sciences

Mutations of the BRAF gene in human cancer

H Davies et al.

NATURE (2002)