4.6 Article

Anti-Aβ Drug Screening Platform Using Human iPS Cell-Derived Neurons for the Treatment of Alzheimer's Disease

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Pharmacology & Pharmacy

The Use of Induced Pluripotent Stem Cells in Drug Development

H. Inoue et al.

CLINICAL PHARMACOLOGY & THERAPEUTICS (2011)

Correction Clinical Neurology

Alzheimer's disease: clinical trials and drug development (vol 9, pg 702, 2010)

F. Mangialasche et al.

LANCET NEUROLOGY (2011)

Article Multidisciplinary Sciences

Investigating synapse formation and function using human pluripotent stem cell-derived neurons

Ji-Eun Kim et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)

Article Clinical Neurology

Diagnosis-Independent Alzheimer Disease Biomarker Signature in Cognitively Normal Elderly People

Geert De Meyer et al.

ARCHIVES OF NEUROLOGY (2010)

Article Biochemistry & Molecular Biology

Brain Endothelial Cells Produce Amyloid β from Amyloid Precursor Protein 770 and Preferentially Secrete the O-Glycosylated Form

Shinobu Kitazume et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2010)

Article Neurosciences

Efficient Four-Drug Cocktail Therapy Targeting Amyloid-β Peptide for Alzheimer's Disease

Masashi Asai et al.

JOURNAL OF NEUROSCIENCE RESEARCH (2010)

Review Clinical Neurology

Alzheimer's disease: clinical trials and drug development

Francesca Mangialasche et al.

LANCET NEUROLOGY (2010)

Article Biotechnology & Applied Microbiology

Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling

Stuart M. Chambers et al.

NATURE BIOTECHNOLOGY (2009)

Article Multidisciplinary Sciences

γ-Secretase Heterogeneity in the Aph1 Subunit: Relevance for Alzheimer's Disease

Lutgarde Serneels et al.

SCIENCE (2009)

Article Biochemistry & Molecular Biology

The amyloid-β rise and γ-secretase inhibitor potency depend on the level of substrate expression

Catherine R. Burton et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2008)

Article Biochemistry & Molecular Biology

Effects of Grape Seed-derived Polyphenols on Amyloid β-Protein Self-assembly and Cytotoxicity

Kenjiro Ono et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2008)

Article Multidisciplinary Sciences

Substrate-targeting γ-secretase modulators

Thomas L. Kukar et al.

NATURE (2008)

Article Multidisciplinary Sciences

An intrinsic mechanism of corticogenesis from embryonic stem cells

Nicolas Gaspard et al.

NATURE (2008)

Article Biotechnology & Applied Microbiology

Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts

Masato Nakagawa et al.

NATURE BIOTECHNOLOGY (2008)

Article Multidisciplinary Sciences

Induced pluripotent stem cell lines derived from human somatic cells

Junying Yu et al.

SCIENCE (2007)

Article Biochemistry & Molecular Biology

Induction of pluripotent stem cells from adult human fibroblasts by defined factors

Kazutoshi Takahashi et al.

Review Genetics & Heredity

Presenilin diversifies its portfolio

Annette L. Parks et al.

TRENDS IN GENETICS (2007)

Review Medicine, General & Internal

Alzheimer's disease

Kaj Blennow et al.

LANCET (2006)

Review Pharmacology & Pharmacy

Metabolism of amyloid-β peptide and Alzheimer's disease

N Iwata et al.

PHARMACOLOGY & THERAPEUTICS (2005)

Article Biochemistry & Molecular Biology

Homo- and heterodimerization of APP family members promotes intercellular adhesion

P Soba et al.

EMBO JOURNAL (2005)

Article Neurosciences

Directed differentiation of telencephalic precursors from embryonic stem cells

K Watanabe et al.

NATURE NEUROSCIENCE (2005)

Article Chemistry, Medicinal

Structure-based design of potent and selective cell-permeable inhibitors of human β-secretase (BACE-1)

SJ Stachel et al.

JOURNAL OF MEDICINAL CHEMISTRY (2004)

Letter Biochemistry & Molecular Biology

Elevated beta-secretase expression and enzymatic activity detected in sporadic Alzheimer disease

LB Yang et al.

NATURE MEDICINE (2003)

Article Multidisciplinary Sciences

Alzheimer's disease is a synaptic failure

DJ Selkoe

SCIENCE (2002)

Article Biochemistry & Molecular Biology

Presenilin-1 and-2 are molecular targets for γ-secretase inhibitors

D Seiffert et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2000)