相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Abnormal mitochondrial dynamics, mitochondrial loss and mutant huntingtin oligomers in Huntington's disease: implications for selective neuronal damage
Ulziibat Shirendeb et al.
HUMAN MOLECULAR GENETICS (2011)
Huntington's disease: from molecular pathogenesis to clinical treatment
Christopher A. Ross et al.
LANCET NEUROLOGY (2011)
Mutant huntingtin binds the mitochondrial fission GTPase dynamin-related protein-1 and increases its enzymatic activity
Wenjun Song et al.
NATURE MEDICINE (2011)
Nicotinamide improves motor deficits and upregulates PGC-1 alpha and BDNF gene expression in a mouse model of Huntington's disease
Tyisha Hathorn et al.
NEUROBIOLOGY OF DISEASE (2011)
Mitochondrial loss, dysfunction and altered dynamics in Huntington's disease
Jinho Kim et al.
HUMAN MOLECULAR GENETICS (2010)
Therapeutic application of histone deacetylase inhibitors for central nervous system disorders
Aleksey G. Kazantsev et al.
NATURE REVIEWS DRUG DISCOVERY (2008)
The HDAC inhibitor 4b ameliorates the disease phenotype and transcriptional abnormalities in Huntington's disease transgenic mice
Elizabeth A. Thomas et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Involvement of mitochondrial complex II defects in neuronal death produced by N-terminus fragment of mutated Huntingtin
A Benchoua et al.
MOLECULAR BIOLOGY OF THE CELL (2006)
3-Nitropropionic acid: a mitochondrial toxin to uncover physiopathological mechanisms underlying striatal degeneration in Huntington's disease
E Brouillet et al.
JOURNAL OF NEUROCHEMISTRY (2005)
HD CAG repeat implicates a dominant property of huntingtin in mitochondrial energy metabolism
IS Seong et al.
HUMAN MOLECULAR GENETICS (2005)
Mitochondrial respiration and ATP production are significantly impaired in striatal cells expressing mutant Huntingtin
T Milakovic et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Dietary restriction affects striatal glutamate in the MPTP-induced mouse model of nigrostriatal degeneration
HK Holmer et al.
SYNAPSE (2005)
The R6/2 transgenic mouse model of Huntington's disease develops diabetes due to deficient β-cell mass and exocytosis
M Björkqvist et al.
HUMAN MOLECULAR GENETICS (2005)
Treatment of Parkinson disease with diet-induced hyperketonemia: A feasibility study
TB VanItallie et al.
NEUROLOGY (2005)
Neuroprotective effects of phenylbutyrate in the N171-82Q transgenic mouse model of Huntington's disease
G Gardian et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Synaptic dysfunction in Huntington's disease: a new perspective
R Smith et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2005)
Effects of β-hydroxybutyrate on cognition in memory-impaired adults
MA Reger et al.
NEUROBIOLOGY OF AGING (2004)
Huntingtin-protein interactions and the pathogenesis of Huntington's disease|
SH Li et al.
TRENDS IN GENETICS (2004)
Increased cerebral uptake and oxidation of exogenous βHB improves ATP following traumatic brain injury in adult rats
ML Prins et al.
JOURNAL OF NEUROCHEMISTRY (2004)
Caloric restriction increases neurotrophic factor levels and attenuates neurochemical and behavioral deficits in a primate model of Parkinson's disease
N Maswood et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
A cell-based screen for drugs to treat Huntington's disease
CT Aiken et al.
NEUROBIOLOGY OF DISEASE (2004)
Chemotherapy for the brain: The antitumor antibiotic mithramycin prolongs survival in a mouse model of Huntington's disease
RJ Ferrante et al.
JOURNAL OF NEUROSCIENCE (2004)
Genetic mouse models of Huntington's and Parkinson's diseases: illuminating but imperfect
MS Levine et al.
TRENDS IN NEUROSCIENCES (2004)
D-β-hydroxybutyrate rescues mitochondrial respiration and mitigates features of Parkinson disease
K Tieu et al.
JOURNAL OF CLINICAL INVESTIGATION (2003)
Intermittent fasting dissociates beneficial effects of dietary restriction on glucose metabolism and neuronal resistance to injury from calorie intake
RM Anson et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Suberoylanilide hydroxamic acid, a histone deacetylase inhibitor, ameliorates motor deficits in a mouse model of Huntington's disease
E Hockly et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Huntington's disease of the endocrine pancreas: Insulin deficiency and diabetes mellitus due to impaired insulin gene expression
OA Andreassen et al.
NEUROBIOLOGY OF DISEASE (2002)
Mice overexpressing 70-kDa heat shock protein show increased resistance to malonate and 3-nitropropionic acid
A Dedeoglu et al.
EXPERIMENTAL NEUROLOGY (2002)
The role of protein composition in specifying nuclear inclusion formation in polyglutamine disease
YH Chai et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Histone deacetylase inhibitors arrest polyglutamine-dependent neurodegeneration in Drosophila
JS Steffan et al.
NATURE (2001)
The hospital and home use of a 30-second hand-held blood ketone meter: guidelines for clinical practice
TM Wallace et al.
DIABETIC MEDICINE (2001)
Interference by Huntingtin and atrophin-1 with CBP-mediated transcription leading to cellular toxicity
FC Nucifora et al.
SCIENCE (2001)
The Huntington's disease protein interacts with p53 and CREB-binding protein and represses transcription
JS Steffan et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
D-β-hydroxybutyrate protects neurons in models of Alzheimer's and Parkinson's disease
Y Kashiwaya et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
CREB-binding protein sequestration by expanded polyglutamine
A McCampbell et al.
HUMAN MOLECULAR GENETICS (2000)